Search Results - "Rädler, Joachim"

Understanding the Kinetics of Protein–Nanoparticle Corona Formation by Vilanova, Oriol, Mittag, Judith J, Kelly, Philip M, Milani, Silvia, Dawson, Kenneth A, Rädler, Joachim O, Franzese, Giancarlo

“…When a pristine nanoparticle (NP) encounters a biological fluid, biomolecules spontaneously form adsorption layers around the NP, called “protein corona”. The…”
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Multifunctional Nanoparticles by Coordinative Self-Assembly of His-Tagged Units with Metal–Organic Frameworks by Röder, Ruth, Preiß, Tobias, Hirschle, Patrick, Steinborn, Benjamin, Zimpel, Andreas, Höhn, Miriam, Rädler, Joachim O, Bein, Thomas, Wagner, Ernst, Wuttke, Stefan, Lächelt, Ulrich

“…Self-assembly of individual units into multicomponent complexes is a powerful approach for the generation of functional superstructures. We present the…”
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Shape and Interhelical Spacing of DNA Origami Nanostructures Studied by Small-Angle X‑ray Scattering by Fischer, Stefan, Hartl, Caroline, Frank, Kilian, Rädler, Joachim O, Liedl, Tim, Nickel, Bert

“…Scaffolded DNA origami nanostructures enable the self-assembly of arbitrarily shaped objects with unprecedented accuracy. Yet, varying physiological conditions…”
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Emergence and Persistence of Collective Cell Migration on Small Circular Micropatterns by Segerer, Felix J, Thüroff, Florian, Piera Alberola, Alicia, Frey, Erwin, Rädler, Joachim O

“…The spontaneous formation of vortices is a hallmark of collective cellular activity. Here, we study the onset and persistence of coherent angular motion as a…”
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Colchicine-Loaded Lipid Bilayer-Coated 50 nm Mesoporous Nanoparticles Efficiently Induce Microtubule Depolymerization upon Cell Uptake by Cauda, Valentina, Engelke, Hanna, Sauer, Anna, Arcizet, Delphine, Rädler, Joachim, Bein, Thomas

“…We report on a one-step assembly route where supported lipid bilayers (SLB) are deposited on functionalized colloidal mesoporous silica (CMS) nanoparticles,…”
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Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers by Zimpel, Andreas, Preiß, Tobias, Röder, Ruth, Engelke, Hanna, Ingrisch, Michael, Peller, Michael, Rädler, Joachim O, Wagner, Ernst, Bein, Thomas, Lächelt, Ulrich, Wuttke, Stefan

“…Selective functionalization of the external surface of porous nanoparticles is of great interest for numerous potential applications in the field of…”
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Reversible versus Irreversible Binding of Transferrin to Polystyrene Nanoparticles: Soft and Hard Corona by Milani, Silvia, Baldelli Bombelli, Francesca, Pitek, Andrzej S, Dawson, Kenneth A, Rädler, Joachim

“…Protein adsorption to nanoparticles (NPs) is a key prerequisite to understand NP–cell interactions. While the layer thickness of the protein corona has been…”
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Nanoscale FasL Organization on DNA Origami to Decipher Apoptosis Signal Activation in Cells by Berger, Ricarda M. L., Weck, Johann M., Kempe, Simon M., Hill, Oliver, Liedl, Tim, Rädler, Joachim O., Monzel, Cornelia, Heuer‐Jungemann, Amelie

“…Cell signaling is initiated by characteristic protein patterns in the plasma membrane, but tools to decipher their molecular organization and activation are…”
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Learning the dynamics of cell–cell interactions in confined cell migration by Brückner, David B., Arlt, Nicolas, Fink, Alexandra, Ronceray, Pierre, Rädler, Joachim O., Broedersz, Chase P.

“…The migratory dynamics of cells in physiological processes, ranging from wound healing to cancer metastasis, rely on contactmediated cell–cell interactions…”
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Shear-Induced Unfolding and Enzymatic Cleavage of Full-Length VWF Multimers by Lippok, Svenja, Radtke, Matthias, Obser, Tobias, Kleemeier, Lars, Schneppenheim, Reinhard, Budde, Ulrich, Netz, Roland R., Rädler, Joachim O.

“…Proteolysis of the multimeric blood coagulation protein von Willebrand Factor (VWF) by ADAMTS13 is crucial for prevention of microvascular thrombosis. ADAMTS13…”
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MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells by Wuttke, Stefan, Braig, Simone, Preiß, Tobias, Zimpel, Andreas, Sicklinger, Johannes, Bellomo, Claudia, Rädler, Joachim O, Vollmar, Angelika M, Bein, Thomas

“…We report the synthesis of MOF@lipid nanoparticles as a versatile and powerful novel class of nanocarriers based on metal-organic frameworks (MOFs). We show…”
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On multistability and constitutive relations of cell motion on fibronectin lanes by Falcke, Martin, Amiri, Behnam, Heyn, Johannes, Schreiber, Christoph, Rädler, Joachim O.

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On the adhesion–velocity relation and length adaptation of motile cells on stepped fibronectin lanes by Schreiber, Christoph, Amiri, Behnam, Heyn, Johannes C. J., Rädler, Joachim O., Falcke, Martin

“…The biphasic adhesion–velocity relation is a universal observation in mesenchymal cell motility. It has been explained by adhesion-promoted forces pushing the…”
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Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A by Ljepoja, Bojan, Schreiber, Christoph, Gegenfurtner, Florian A, García-Roman, Jonathan, Köhler, Bianca, Zahler, Stefan, Rädler, Joachim O, Wagner, Ernst, Roidl, Andreas

“…Cancer progression and metastases are frequently related to changes of cell motility. Amongst others, the microRNA-200c (miR-200c) was shown to maintain the…”
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Photolithographic microfabrication of hydrogel clefts for cell invasion studies by Stöberl, Stefan, Balles, Miriam, Kellerer, Thomas, Rädler, Joachim O

“…Invasion of migrating cells into surrounding tissue plays a key role in cancer metastasis and immune response. In order to assess invasiveness, most invasion…”
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Flow and Diffusion in Channel-Guided Cell Migration by Marel, Anna-Kristina, Zorn, Matthias, Klingner, Christoph, Wedlich-Söldner, Roland, Frey, Erwin, Rädler, Joachim O.

“…Collective migration of mechanically coupled cell layers is a notable feature of wound healing, embryonic development, and cancer progression. In confluent…”
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Self-Assembly of Tunable Intrinsically Disordered Peptide Amphiphiles by Ehm, Tamara, Shinar, Hila, Jacoby, Guy, Meir, Sagi, Koren, Gil, Segal Asher, Merav, Korpanty, Joanna, Thompson, Matthew P., Gianneschi, Nathan C., Kozlov, Michael M., Azoulay-Ginsburg, Salome, Amir, Roey J., Rädler, Joachim O., Beck, Roy

“…Intrinsically disordered peptide amphiphiles (IDPAs) present a novel class of synthetic conjugates that consist of short hydrophilic polypeptides anchored to…”
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Geometry-Sensitive Protrusion Growth Directs Confined Cell Migration by Flommersfeld, Johannes, Stöberl, Stefan, Shah, Omar, Rädler, Joachim O, Broedersz, Chase P

“…The migratory dynamics of cells can be influenced by the complex microenvironment through which they move. It remains unclear how the motility machinery of…”
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Age related changes in cell stiffness of tendon stem/progenitor cells and a rejuvenating effect of ROCK-inhibition by Kiderlen, Stefanie, Polzer, Christoph, Rädler, Joachim O., Docheva, Denitsa, Clausen-Schaumann, Hauke, Sudhop, Stefanie

“…Tendon stem/progenitor cells (TSPC) are potential targets for regenerative medicine and the treatment of tendon injuries. The frequency of such injuries…”
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Nanosized Multifunctional Polyplexes for Receptor-Mediated SiRNA Delivery by Dohmen, Christian, Edinger, Daniel, Fröhlich, Thomas, Schreiner, Laura, Lächelt, Ulrich, Troiber, Christina, Rädler, Joachim, Hadwiger, Philipp, Vornlocher, Hans-Peter, Wagner, Ernst

“…Although our understanding of RNAi and our knowledge on designing and synthesizing active and safe siRNAs significantly increased during the past decade,…”
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