Search Results - "RYO, Akihide"
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Potent antiviral effect of silver nanoparticles on SARS-CoV-2
Published in Biochemical and biophysical research communications (26-11-2020)“…The pandemic of COVID-19 is spreading unchecked due to the lack of effective antiviral measures. Silver nanoparticles (AgNP) have been studied to possess…”
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Interpreting Diagnostic Tests for SARS-CoV-2
Published in JAMA : the journal of the American Medical Association (09-06-2020)Get full text
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Galectin-9 restricts hepatitis B virus replication via p62/SQSTM1-mediated selective autophagy of viral core proteins
Published in Nature communications (27-01-2022)“…Autophagy has been linked to a wide range of functions, including a degradative process that defends host cells against pathogens. Although the involvement of…”
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Treating COVID-19: are we missing out the window of opportunity?
Published in Journal of antimicrobial chemotherapy (19-01-2021)“…Abstract Severe COVID-19 is a biphasic illness, with an initial viral replication phase, followed by a cascade of inflammatory events. Progression to severe…”
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Salinomycin kills cancer stem cells by sequestering iron in lysosomes
Published in Nature chemistry (01-10-2017)“…Cancer stem cells (CSCs) represent a subset of cells within tumours that exhibit self-renewal properties and the capacity to seed tumours. CSCs are typically…”
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Vaccine-induced humoral response against SARS-CoV-2 dramatically declined but cellular immunity possibly remained at 6 months post BNT162b2 vaccination
Published in Vaccine (26-04-2022)“…•Both IgG against spike protein (SP IgG) and 50% neutralizing antibody markedly decreased at 6-month post-vaccination.•SP IgG titer had a negative correlation…”
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Reduced Replication Efficacy of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant in “Mini-gut” Organoids
Published in Gastroenterology (New York, N.Y. 1943) (01-08-2022)Get full text
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Epidermal growth factor receptor is a host-entry cofactor triggering hepatitis B virus internalization
Published in Proceedings of the National Academy of Sciences - PNAS (23-04-2019)“…Sodium taurocholate cotransporting polypeptide (NTCP) is a host cell receptor required for hepatitis B virus (HBV) entry. However, the susceptibility of…”
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Whole Nucleocapsid Protein of Severe Acute Respiratory Syndrome Coronavirus 2 May Cause False-Positive Results in Serological Assays
Published in Clinical infectious diseases (08-04-2021)Get full text
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Identification of serum prognostic biomarkers of severe COVID-19 using a quantitative proteomic approach
Published in Scientific reports (19-10-2021)“…The COVID-19 pandemic is an unprecedented threat to humanity that has provoked global health concerns. Since the etiopathogenesis of this illness is not fully…”
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Lnc RNA H19 is associated with poor prognosis in breast cancer patients and promotes cancer stemness
Published in Breast cancer research and treatment (01-08-2018)“…Purpose Aldehyde dehydrogenase1 (ALDH1) is widely accepted as a stem cell marker for normal breast as well as in breast cancer. Although the clinical impact of…”
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Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy
Published in Nature (London) (23-07-2015)“…Traumatic brain injury (TBI), characterized by acute neurological dysfunction, is one of the best known environmental risk factors for chronic traumatic…”
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Identification of gravity‐responsive serum proteins in spaceflight mice using a quantitative proteomic approach with data‐independent acquisition mass spectrometry
Published in Proteomics (Weinheim) (01-05-2024)“…Physical inactivity associated with gravity unloading, such as microgravity during spaceflight and hindlimb unloading (HU), can cause various physiological…”
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Rapid quantitative detection system for measles virus‐neutralizing antibodies using HiBiT‐tagged virus‐like particles
Published in Microbiology and immunology (01-04-2024)“…Immunological testing to detect neutralizing antibodies (NAbs) is important in measles (MV) infection control. Currently, the plaque reduction neutralization…”
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HBx-induced degradation of Smc5/6 complex impairs homologous recombination-mediated repair of damaged DNA
Published in Journal of hepatology (01-01-2022)“…HBV causes hepatocellular carcinoma (HCC). While it was recently shown that the ability of HBV X protein (HBx) to impair the Smc5/6 (structural maintenance of…”
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The multi-step mechanism and biological role of noncanonical autophagy targeting Streptococcus pneumoniae during the early stages of infection
Published in Autophagy (02-06-2020)“…Multiple autophagic processes are triggered in response to bacterial infection as the host attempts to eliminate intracellular invaders. However, it is still…”
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Antibody titers against the Alpha, Beta, Gamma, and Delta variants of SARS-CoV-2 induced by BNT162b2 vaccination measured using automated chemiluminescent enzyme immunoassay
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01-02-2022)“…Levels of 50% neutralizing titer (NT50) reflect the a vaccine-induced humoral immunity after the vaccination against the severe acute respiratory syndrome…”
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The machinery for endocytosis of epidermal growth factor receptor coordinates the transport of incoming hepatitis B virus to the endosomal network
Published in The Journal of biological chemistry (17-01-2020)“…Sodium taurocholate cotransporting polypeptide (NTCP) is expressed at the surface of human hepatocytes and functions as an entry receptor of hepatitis B virus…”
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Changes in the astronaut serum proteome during prolonged spaceflight
Published in Proteomics (Weinheim) (01-05-2024)“…The molecular mechanisms associated with spaceflight‐induced biological adaptations that may affect many healthy tissue functions remain poorly understood. In…”
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Functional association of cellular microtubules with viral capsid assembly supports efficient hepatitis B virus replication
Published in Scientific reports (06-09-2017)“…Viruses exploit host factors and environment for their efficient replication. The virus-host interaction mechanisms for achieving an optimal hepatitis B virus…”
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