Search Results - "RYAN, Randall E"

Breast cancer cells stimulate neutrophils to produce oncostatin M : Potential implications for tumor progression by QUEEN, Marisa M, RYAN, Randall E, HOLZER, Ryan G, KELLER-PECK, Cynthia R, JORCYK, Cheryl L

“…Tumor-associated and tumor-infiltrating neutrophils (TAN) and macrophages (TAM) can account for as much as 50% of the total tumor mass in invasive breast…”
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Oncostatin M binds to extracellular matrix in a bioactive conformation: Implications for inflammation and metastasis by Ryan, Randall E., Martin, Bryan, Mellor, Liliana, Jacob, Reed B., Tawara, Ken, McDougal, Owen M., Oxford, Julia Thom, Jorcyk, Cheryl L.

“…Model for OSM role in chronic inflammation and tumor metastasis. Inflammatory cells infiltrate into a particular microenvironment and secrete OSM, which binds…”
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Oncostatin M induces cell detachment and enhances the metastatic capacity of T-47D human breast carcinoma cells by Jorcyk, Cheryl L., Holzer, Ryan G., Ryan, Randall E.

“…Oncostatin M (OSM), an IL-6 family cytokine, has previously been shown to increase migration of several breast cancer cell lines in vitro. Our studies report…”
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Oncostatin M stimulates the detachment of a reservoir of invasive mammary carcinoma cells: role of cyclooxygenase-2 by Holzer, Ryan G, Ryan, Randall E, Tommack, Matt, Schlekeway, Eric, Jorcyk, Cheryl L

“…Previously, oncostatin M (OSM) has been shown to inhibit the proliferation of breast cancer cells in vitro. Circumstantial evidence, however, suggests that OSM…”
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Abstract 2816: Oncostatin M is a proinflammatory cytokine capable of exerting long term biological effects via its binding to ECM components in a bioactive conformation by Ryan, Randall E., Martin, Bryan, Mellor, Liliana, McDougal, Owen, Oxford, Julia, Jorcyk, Cheryl

“…Abstract Oncostatin M (OSM) is a proinflammatory cytokine that has been reported to promote a metastatic phenotype in cancer cells via its effects on cell…”
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Cathepsin B-like activity in viable tumor cells isolated from rodent tumors by RYAN, R. E, CRISSMAN, J. D, HONN, K. V, SLOANE, B. F

“…The cathepsin B-like cysteine proteinase activity which has been implicated in tumor malignancy has been attributed to several cellular sources, including…”
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Properties of a plasma membrane-associated cathepsin B-like cysteine proteinase in metastatic B16 melanoma variants by ROZHIN, J, ROBINSON, D, STEVENS, M. A, LAH, T. T, HONN, K. V, RYAN, R. E, SLOANE, B. F

“…Activities of a cathepsin B-like cysteine proteinase have previously been observed to correlate with the malignancy of several animal and human tumors. Plasma…”
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