Search Results - "RUTSCHOW, Susanne"

Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis by Tschöpe, Carsten, Van Linthout, Sophie, Jäger, Sebastian, Arndt, Robert, Trippel, Tobias, Müller, Irene, Elsanhoury, Ahmed, Rutschow, Susanne, Anker, Stefan D., Schultheiss, Heinz‐Peter, Pauschinger, Matthias, Spillmann, Frank, Pappritz, Kathleen

“…Aims Left ventricular (LV) dysfunction in viral myocarditis is attributed to myocardial inflammation and fibrosis, inducing acute and long‐time cardiac damage…”
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Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis by HEYMANS, Stephane, PAUSCHINGER, Matthias, PADALKO, Elisabeth, NEYTS, Johan, SCHULTHEISS, Heinz-Peter, VAN DE WERF, Frans, CARMELIET, Peter, PINTO, Yigal M, DE PALMA, Armando, KALLWELLIS-OPARA, Angela, RUTSCHOW, Susanne, SWINNEN, Melissa, VANHOUTTE, Davy, FANGYE GAO, TORPAI, Raimund, BAKER, Andrew H

“…Acute viral myocarditis is an important cause of cardiac failure in young adults for which there is no effective treatment apart from general heart failure…”
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Failed MitraClip-procedure with pull out of the anterior leaflet by Gross, Michael, Wilkenshoff, Ursula, Rutschow, Susanne

“…MitraClip is an attractive and less invasive alternative to mitral valve surgery in serve mitral regurgitation in patients with moderate or severe risk for…”
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Contributions of Inflammation and Cardiac Matrix Metalloproteinase Activity to Cardiac Failure in Diabetic Cardiomyopathy by Westermann, Dirk, Rutschow, Susanne, Jäger, Sebastian, Linderer, Anne, Anker, Stefan, Riad, Alexander, Unger, Thomas, Schultheiss, Heinz-Peter, Pauschinger, Matthias, Tschöpe, Carsten

“…Contributions of Inflammation and Cardiac Matrix Metalloproteinase Activity to Cardiac Failure in Diabetic Cardiomyopathy The Role of Angiotensin Type 1…”
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Contributions of inflammation and cardiac matrix metalloproteinase activity to cardiac failure in diabetic cardiomyopathy : The role of angiotensin type 1 receptor antagonism by WESTERMANN, Dirk, RUTSCHOW, Susanne, JÄGER, Sebastian, LINDERER, Anne, ANKER, Stefan, RIAD, Alexander, UNGER, Thomas, SCHULTHEISS, Heinz-Peter, PAUSCHINGER, Matthias, TSCHÖPE, Carsten

“…We investigated the effect of the angiotensin type 1 (AT-1) receptor antagonist, irbesartan, on matrix metalloproteinase (MMP) activity and cardiac cytokines…”
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LEFT VENTRICULAR REMODELING AND MYOCARDIAL MECHANICS OBTAINED BY 2D STRAIN FOR PROGNOSTIC EVALUATION OF CLINICAL IMPROVEMENT IN HEART FAILURE PATIENTS UNDERGOING PERCUTANEOUS MITRAL VALVE REPAIR by Kasner, Mario, Galuszka, Oskar, Rutschow, Susanne, Poller, Wolfgang, Landmesser, Ulf, Gross, Michael C

“…According to the multivariate logistic regression none of echo parameters has proven to be an independent predictor…”
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Myocardial proteases and matrix remodeling in inflammatory heart disease by RUTSCHOW, Susanne, JUN LI, SCHULTHEISS, Heinz-Peter, PAUSCHINGER, Matthias

“…Recently, it has been demonstrated that myocardial inflammation plays a pivotal role in the development and progression of congestive heart failure. The…”
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Left ventricular enlargement in coxsackievirus-B3 induced chronic myocarditis — ongoing inflammation and an imbalance of the matrix degrading system by Rutschow, Susanne, Leschka, Sebastian, Westermann, Dirk, Puhl, Kerstin, Weitz, Anneke, Ladyszenskij, Leonid, Jaeger, Sebastian, Zeichhardt, Heinz, Noutsias, Michel, Schultheiss, Heinz-Peter, Tschope, Carsten, Pauschinger, Matthias

“…Enteroviruses, especially Coxsackie B3 virus (CVB-3), cause acute viral myocarditis, but the detailed mechanisms leading to chronic left ventricular…”
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MitraClip procedure with two MitraClips after indirect annuloplasty with the MONARC device by Rutschow, Susanne, Jäger, Sebastian, Gross, Michael C.

“…Abstract Mitral regurgitation is associated with a worsened prognosis in dilated cardiomyopathy. First standard therapy consists of a mitral valve…”
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MitraClip-procedure with two Mitra-Clips after indirect anuloplasty with the MONARC-device by Susanne Rutschow, Sebastian Jäger, Michael C. Gross

“…Mitral regurgitation is associated with a worsened prognosis in dilated cardiomyopathy. First standard therapy consists of a mitral valve reconstruction…”
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MitraClip-procedure with two Mitra-Clips after indirect anuloplasty with the MONARC-device by Michael Gross, sebastian.jaeger@charite.de, Susanne Rutschow

“…Mitral regurgitation is associated with a worsened prognosis in dilated cardiomyopathy. First standard therapy consists of a mitral valve reconstruction…”
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Failed MitraClip procedure with pull out of the anterior leaflet by Rutschow, Susanne, Wilkenshoff, Ursula, Gross, Michael C.

“…Abstract MitraClip is an attractive and less invasive alternative to mitral valve surgery in serve mitral regurgitation in patients with moderate or severe…”
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Diltiazem treatment prevents diastolic heart failure in mice with familial hypertrophic cardiomyopathy by Westermann, Dirk, Knollmann, Björn C., Steendijk, Paul, Rutschow, Susanne, Riad, Alexander, Pauschinger, Matthias, Potter, James D., Schultheiss, Heinz-Peter, Tschöpe, Carsten

“…Abstract Background: The cardiac troponin T I79N mutation, linked to familial hypertrophic cardiomyopathy, carries a high risk of sudden cardiac death even in…”
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Carvedilol improves left ventricular function in murine coxsackievirus-induced acute myocarditis Association with reduced myocardial interleukin-1β and MMP-8 expression and a modulated immune response by Pauschinger, Matthias, Rutschow, Susanne, Chandrasekharan, Kumaran, Westermann, Dirk, Weitz, Anneke, Schwimmbeck, Lothar Peter, Zeichhardt, Heinz, Poller, Wolfgang, Noutsias, Michel, Li, Jun, Schultheiss, Heinz-Peter, Tschope, Carsten

“…Background Proinflammatory cytokines induce the expression of matrix metalloproteinases that play a crucial role in myocardial remodeling. Beta‐adrenergic…”
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Immunomodulation by interleukin-4 suppresses matrix metalloproteinases and improves cardiac function in murine myocarditis by Li, Jun, Leschka, Sebastian, Rutschow, Susanne, Schwimmbeck, Peter Lothar, Husmann, Lars, Noutsias, Michel, Westermann, Dirk, Poller, Wolfgang, Zeichhardt, Heinz, Klingel, Karin, Tschope, Carsten, Schultheiss, Heinz-Peter, Pauschinger, Matthias

“…Immune response is critically involved in determining the course of viral myocarditis and immunomodulation. Different cytokines may have either deleterious or…”
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Collagen degradation in a murine myocarditis model: relevance of matrix metalloproteinase in association with inflammatory induction by JUN LIA, SCHWIMMBECK, Peter Lothar, SPILLMANN, Frank, ZEICHHARDT, Heinz, SCHULTHEISS, Heinz-Peter, PAUSCHINGER, Matthias, TSCHOPE, Carsten, LESCHKA, Sebastian, HUSMANN, Lars, RUTSCHOW, Susanne, REICHENBACH, Florian, NOUTSIAS, Michel, KOBALZ, Ursula, POLLER, Wolfgang

“…Myocardial collagen degradation is regulated by matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinase (TIMPs). The possible…”
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Abstract 2188: Imbalance In The Mmp timp-system And Myocardial Fibrosis In Patients With Inflammatory Cardiomyopathy by Rutschow, Susanne, Lettau, Olga, Jaeger, Sebastian, Bock, Matthias, Puhl, Kerstin, Kuehl, Uwe, Noutsias, Michael, Schultheiss, Heinz P, Pauschinger, Matthias

“…Abstract only Introduction: Inflammation and/or viral infection are both relevant for extracellular matrix remodeling. Therefore the effects of myocardial…”
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Abstract 1707: Analysis Of Extracellular Matrix Remodeling On Endomyocardial Biopsies From Patients With Inflammatory Cardiomyopathy by Lettau, Olga, Rutschow, Susanne, Jaeger, Sebastian, Kuehl, Uwe, Puhl, Kerstin, Noutsias, Michael, Schultheiss, Heinz P, Pauschinger, Matthias

“…Abstract only Introduction: The biopsy based analyse, with histological, immunohistological and molecular biological analysis of myocardial tissues, represents…”
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Hemodynamic characterization of left ventricular function in experimental coxsackieviral myocarditis: effects of carvedilol and metoprolol by Tschöpe, Carsten, Westermann, Dirk, Steendijk, Paul, Noutsias, Michael, Rutschow, Susanne, Weitz, Anneke, Schwimmbeck, Peter Lothar, Schultheiss, Heinz-Peter, Pauschinger, Matthias

“…Background: Carvedilol, a vasodilating nonselective β-adrenoceptor antagonist, but not metoprolol, a selective β 1-adrenoceptor antagonist, has been shown to…”
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Carvedilol improves left ventricular function in murine coxsackievirus-induced acute myocarditis association with reduced myocardial interleukin-1beta and MMP-8 expression and a modulated immune response by Pauschinger, Matthias, Rutschow, Susanne, Chandrasekharan, Kumaran, Westermann, Dirk, Weitz, Anneke, Peter Schwimmbeck, Lothar, Zeichhardt, Heinz, Poller, Wolfgang, Noutsias, Michel, Li, Jun, Schultheiss, Heinz-Peter, Tschope, Carsten

“…Proinflammatory cytokines induce the expression of matrix metalloproteinases that play a crucial role in myocardial remodeling. Beta-adrenergic receptor…”
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