Search Results - "RUSS, A"

Epigenetic Memory and Preferential Lineage-Specific Differentiation in Induced Pluripotent Stem Cells Derived from Human Pancreatic Islet Beta Cells by Bar-Nur, Ori, Russ, Holger A., Efrat, Shimon, Benvenisty, Nissim

“…Human induced pluripotent stem cells (HiPSCs) appear to be highly similar to human embryonic stem cells (HESCs). Using two genetic lineage-tracing systems, we…”
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A National Profile of Childhood Epilepsy and Seizure Disorder by RUSS, Shirley A, LARSON, Kandyce, HALFON, Neal

“…To determine sociodemographics, patterns of comorbidity, and function of US children with reported epilepsy/seizure disorder. Bivariate and multivariable…”
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Human islets contain four distinct subtypes of β cells by Dorrell, Craig, Schug, Jonathan, Canaday, Pamela S., Russ, Holger A., Tarlow, Branden D., Grompe, Maria T., Horton, Tamara, Hebrok, Matthias, Streeter, Philip R., Kaestner, Klaus H., Grompe, Markus

“…Human pancreatic islets of Langerhans contain five distinct endocrine cell types, each producing a characteristic hormone. The dysfunction or loss of the…”
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STATISTICAL TESTS OF GALACTIC DYNAMO THEORY by Chamandy, Luke, Shukurov, Anvar, Russ Taylor, A.

“…ABSTRACT Mean-field galactic dynamo theory is the leading theory to explain the prevalence of regular magnetic fields in spiral galaxies, but its systematic…”
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Human pancreatic beta-like cells converted from fibroblasts by Zhu, Saiyong, Russ, Holger A., Wang, Xiaojing, Zhang, Mingliang, Ma, Tianhua, Xu, Tao, Tang, Shibing, Hebrok, Matthias, Ding, Sheng

“…Pancreatic beta cells are of great interest for biomedical research and regenerative medicine. Here we show the conversion of human fibroblasts towards an…”
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Replication confers β cell immaturity by Puri, Sapna, Roy, Nilotpal, Russ, Holger A., Leonhardt, Laura, French, Esra K., Roy, Ritu, Bengtsson, Henrik, Scott, Donald K., Stewart, Andrew F., Hebrok, Matthias

“…Pancreatic β cells are highly specialized to regulate systemic glucose levels by secreting insulin. In adults, increase in β-cell mass is limited due to brakes…”
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Quantitative PET-based biomarkers in lymphoma: getting ready for primetime by Alderuccio, Juan Pablo, Kuker, Russ A., Yang, Fei, Moskowitz, Craig H.

“…The use of functional quantitative biomarkers extracted from routine PET–CT scans to characterize clinical responses in patients with lymphoma is gaining…”
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The first super geomagnetic storm of solar cycle 24: “The St. Patrick’s day event (17 March 2015)” by Wu, Chin-Chun, Liou, Kan, Lepping, Ronald P., Hutting, Lynn, Plunkett, Simon, Howard, Russ A., Socker, Dennis

“…The first super geomagnetic storm (Dst < −200 nT) of solar cycle 24 occurred on “St. Patrick’s day” (17 March 2015). Notably, it was a two-step storm. The…”
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Calciphylaxis in a 30-Year-Old Woman With Alcoholic Cirrhosis: A Case Report by Parra, Adrian, Kuker, Russ A

“…A diagnosis of calciphylaxis is rare amongst the vulnerable population of patients with end-stage renal disease (ESRD); however, it has poor outcomes when it…”
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FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences by Goering, Raeann, Hudish, Laura I, Guzman, Bryan B, Raj, Nisha, Bassell, Gary J, Russ, Holger A, Dominguez, Daniel, Taliaferro, J Matthew

“…The sorting of RNA molecules to subcellular locations facilitates the activity of spatially restricted processes. We have analyzed subcellular transcriptomes…”
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From the dish to humans: A stem cell recipe for success by Russ, Holger A, Shilleh, Ali H, Sussel, Lori

“…Islet transplantation has proven to be an effective treatment for type 1 diabetes (T1D) yet is hampered by the shortage of available tissue. Recently, two…”
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Small Molecules Facilitate the Reprogramming of Mouse Fibroblasts into Pancreatic Lineages by Li, Ke, Zhu, Saiyong, Russ, Holger A., Xu, Shaohua, Xu, Tao, Zhang, Yu, Ma, Tianhua, Hebrok, Matthias, Ding, Sheng

“…Pancreatic β cells are of great interest for the treatment of type 1 diabetes. A number of strategies already exist for the generation of β cells, but a…”
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Loss of the transcription factor MAFB limits β-cell derivation from human PSCs by Russell, Ronan, Carnese, Phichitpol P., Hennings, Thomas G., Walker, Emily M., Russ, Holger A., Liu, Jennifer S., Giacometti, Simone, Stein, Roland, Hebrok, Matthias

“…Next generation sequencing studies have highlighted discrepancies in β-cells which exist between mice and men. Numerous reports have identified MAF BZIP…”
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Sox9 regulates alternative splicing and pancreatic beta cell function by Puri, Sapna, Maachi, Hasna, Nair, Gopika, Russ, Holger A., Chen, Richard, Pulimeno, Pamela, Cutts, Zachary, Ntranos, Vasilis, Hebrok, Matthias

“…Despite significant research, mechanisms underlying the failure of islet beta cells that result in type 2 diabetes (T2D) are still under investigation. Here,…”
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Epithelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells by Russ, Holger A, Ravassard, Philippe, Kerr-Conte, Julie, Pattou, Francois, Efrat, Shimon

“…In-vitro expansion of functional beta cells from adult human islets is an attractive approach for generating an abundant source of cells for beta-cell…”
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High-Fat Diet-Induced Mitochondrial Biogenesis Is Regulated by Mitochondrial-Derived Reactive Oxygen Species Activation of CaMKII by JAIN, Swati S, PAGLIALUNGA, Sabina, HOLLOWAY, Graham P, VIGNA, Chris, LUDZKI, Alison, HERBST, Eric A, LALLY, James S, SCHRAUWEN, Patrick, HOEKS, Joris, TUPLING, A. Russ, BONEN, Arend

“…Calcium/calmodulin-dependent protein kinase (CaMK) activation induces mitochondrial biogenesis in response to increasing cytosolic calcium concentrations…”
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In Vitro Proliferation of Cells Derived From Adult Human β-Cells Revealed By Cell-Lineage Tracing by Russ, Holger A, Bar, Yael, Ravassard, Philippe, Efrat, Shimon

“…In Vitro Proliferation of Cells Derived From Adult Human β-Cells Revealed By Cell-Lineage Tracing Holger A. Russ 1 , Yael Bar 1 , Philippe Ravassard 2 and…”
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The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma by von Figura, Guido, Fukuda, Akihisa, Roy, Nilotpal, Liku, Muluye E., Morris IV, John P., Kim, Grace E., Russ, Holger A., Firpo, Matthew A., Mulvihill, Sean J., Dawson, David W., Ferrer, Jorge, Mueller, William F., Busch, Anke, Hertel, Klemens J., Hebrok, Matthias

“…Pancreatic ductal adenocarcinoma (PDA) develops through distinct precursor lesions, including pancreatic intraepithelial neoplasia (PanIN) and intraductal…”
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Generation of Functional Thymic Epithelium from Human Embryonic Stem Cells that Supports Host T Cell Development by Parent, Audrey V., Russ, Holger A., Khan, Imran S., LaFlam, Taylor N., Metzger, Todd C., Anderson, Mark S., Hebrok, Matthias

“…Inducing immune tolerance to prevent rejection is a key step toward successful engraftment of stem-cell-derived tissue in a clinical setting. Using human…”
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Protecting Stem Cell Derived Pancreatic Beta-Like Cells From Diabetogenic T Cell Recognition by Castro-Gutierrez, Roberto, Alkanani, Aimon, Mathews, Clayton E, Michels, Aaron, Russ, Holger A

“…Type 1 diabetes results from an autoimmune attack directed at pancreatic beta cells predominantly mediated by T cells. Transplantation of stem cell derived…”
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