Search Results - "RUSHMERE, Neil K."

Soluble Forms of Toll-Like Receptor (TLR)2 Capable of Modulating TLR2 Signaling Are Present in Human Plasma and Breast Milk by LeBouder, Emmanuel, Rey-Nores, Julia E, Rushmere, Neil K, Grigorov, Martin, Lawn, Stephen D, Affolter, Michael, Griffin, George E, Ferrara, Pascual, Schiffrin, Eduardo J, Morgan, B. Paul, Labeta, Mario O

“…Dysregulation of the initial, innate immune response to bacterial infection may lead to septic shock and death. Toll-like receptors (TLRs) play a crucial role…”
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Spontaneous Classical Pathway Activation and Deficiency of Membrane Regulators Render Human Neurons Susceptible to Complement Lysis by Singhrao, Sim K., Neal, James W., Rushmere, Neil K., Morgan, B. Paul, Gasque, Philippe

“…This study investigated the capacity of neurons and astrocytes to spontaneously activate the complement system and control activation by expressing complement…”
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Molecular cloning, expression, function and immunoreactivities of members of a gene family of sphingomyelinases from Loxosceles venom glands by Tambourgi, Denise V, Pedrosa, Matheus de F.Fernandes, van den Berg, Carmen W, Gonçalves-de-Andrade, Rute M, Ferracini, Matheus, Paixão-Cavalcante, Danielle, Morgan, B.Paul, Rushmere, Neil K

“…Loxoscelism is the clinical condition produced by the venom of spiders belonging to the genus Loxosceles, which can be observed as two well-defined clinical…”
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Analysis of the level of mRNA expression of the membrane regulators of complement, CD59, CD55 and CD46, in breast cancer by Rushmere, Neil K., Knowlden, Janice M., Gee, Julia M.W., Harper, Maureen E., Robertson, John F., Morgan, B. Paul, Nicholson, Robert I.

“…We have examined the relative mRNA expression of the complement (C) regulatory proteins CD59, CD55 and CD46 in RNA isolated from 50 primary breast cancer…”
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Do poor-prognosis breast tumours express membrane cofactor proteins (CD46)? by MADJD, Zahra, DURRANT, Lindy G, PINDER, Sarah E, ELLIS, Ian O, RONAN, John, LEWIS, Sarah, RUSHMERE, Neil K, SPENDLOVE, Ian

“…CD46 or membrane cofactor protein (MCP) is a complement regulatory protein that has been identified on all nucleated cells and which protects them from attack…”
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Mutational analysis of the active site and antibody epitopes of the complement-inhibitory glycoprotein, CD59 by Bodian, D L, Davis, S J, Morgan, B P, Rushmere, N K

“…The Ly-6 superfamily of cell surface molecules includes CD59, a potent regulator of the complement system that protects host cells from the cytolytic action of…”
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Molecular Cloning and Functional Characterization of the Pig Analogue of CD59: Relevance to Xenotransplantation by Hinchliffe, Stewart J, Rushmere, Neil K, Hanna, S. Melanie, Morgan, B. Paul

“…In this work, we report the cloning of the cDNA for the porcine analogue of human CD59. Degenerate primers, derived from the N-terminal sequence of pig…”
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Function of the Factor I Modules (FIMS) of Human Complement Component C6 by DiScipio, Richard G., Linton, Stuart M., Rushmere, Neil K.

“…In order to elucidate the function of complement component C6, truncated C6 molecules were expressed recombinantly. These were either deleted of the factor I…”
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Molecular Cloning and Functional Characterization of the Rat Analogue of Human Decay-Accelerating Factor (CD55) by Hinchliffe, Stewart J, Spiller, O. Brad, Rushmere, Neil K, Morgan, B. Paul

“…We report here the cloning of cDNAs encoding two forms of the rat analogue of human decay-accelerating factor (DAF; CD55). Screening of a rat kidney cDNA…”
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Differential expression of individual complement regulators in the brain and choroid plexus by Singhrao, S K, Neal, J W, Rushmere, N K, Morgan, B P, Gasque, P

“…Membrane bound regulators of complement (C) control the system at key points during activation. To determine whether C regulators were expressed in the central…”
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Molecular and functional analysis of mouse decay accelerating factor (CD55) by Harris, C L, Rushmere, N K, Morgan, B P

“…Molecular cloning of mouse decay accelerating factor (DAF; CD55) predicted two forms of the molecule, one transmembrane (TM) and the other…”
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Molecular cloning, chromosomal localization, expression, and functional characterization of the mouse analogue of human CD59 by Powell, MB, Marchbank, KJ, Rushmere, NK, van den Berg, CW, Morgan, BP

“…We have previously described the isolation and cloning of the rat analogue of the human complement inhibitor CD59 (hCD59). Using the rat CD59 (rCD59) coding…”
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Molecular and functional analysis of mouse decay accelerating factor (CD55) by HARRIS, Claire L., RUSHMERE, Neil K., Paul MORGAN, B.

“…Molecular cloning of mouse decay accelerating factor (DAF; CD55) predicted two forms of the molecule, one transmembrane (TM) and the other…”
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Function of the factor I modules (FIMS) of human complement component C6 by DiScipio, Richard G., Rushmere, Neil K.

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Cloning of rat DAF: Two forms on a single gene by Hinchliffe, Stewart J., Spiller, O.Brad, Rushmere, Neil K., Morgan, B.Paul

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Production and functional characterisation of a soluble recombinant form of mouse CD59 by Rushmere, Neil K., van den Berg, Carmen W., Morgan, B.Paul

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Mapping the Regions of the Complement Inhibitor CD59 Responsible for Its Species Selective Activity by Yu, Jinghua, Dong, Shanghong, Rushmere, Neil K., Morgan, B. Paul, Abagyan, Ruben, Tomlinson, Stephen

“…CD59 is a widely distributed membrane-bound glycoprotein that inhibits the formation of the cytolytic membrane attack complex (MAC) of complement on host…”
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Knocking out mouse CD59 using a PCR derived gene targeting vector by Holt, Dewi S., Botto, Marina, Bygrave, Anne E., Rushmere, Neil K., Walport, Mark J., Paul Morgan, B.

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Regulatory regions of androgen-responsive genes by Davies, P, Rushmere, N K

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Intronic steroid response elements in prostate binding protein genes by Rushmere, N K, Claessens, F, Peeters, B, Rombauts, W, Davies, P

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