Search Results - "RUSH, L. J"

Loss of the tumor suppressor PML in human cancers of multiple histologic origins by GURRIERI, Carmela, CAPODIECI, Paola, BERNARDI, Rosa, SCAGLIONI, Pier Paolo, NAFA, Khedoudja, RUSH, Laura J, VERBEL, David A, CORDON-CARDO, Carlos, PANDOLFI, Pier Paolo

“…The PML gene is fused to the RARalpha gene in the vast majority of acute promyelocytic leukemias (APL) and has been implicated in the control of key…”
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Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic cells by KLISOVIC, M. I, MAGHRABY, E. A, RUSH, L. J, PLASS, C, GREVER, M. R, BYRD, J. C, MARCUCCI, G, PARTHUN, M. R, GUIMOND, M, SKLENAR, A. R, WHITMAN, S. P, CHAN, K. K, MURPHY, T, ANON, J, ARCHER, K. J

“…In t(8;21) acute myeloid leukemia (AML), the AML1/ETO fusion protein promotes leukemogenesis by recruiting histone deacetylase (HDAC) and silencing AML1target…”
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Differential targets of CpG island hypermethylation in primary and metastatic head and neck squamous cell carcinoma (HNSCC) by Smiraglia, D J, Smith, L T, Lang, J C, Rush, L J, Dai, Z, Schuller, D E, Plass, C

“…Head and neck squamous cell carcinomas (HNSCC) often metastasise to the cervical lymph nodes. It is known for HNSCC as well as other cancers that progression…”
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Spontaneous ulcerations of the breast by Matlock, S. M., Rush, J. L., Afzal, W., Fulton, E. H., Berney, S. M., Wong, H. K.

“…Click here for the corresponding questions to this CME article…”
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Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci by Rush, Laura J., Dai, Zunyan, Smiraglia, Dominic J., Gao, Xin, Wright, Fred A., Frühwald, Michael, Costello, Joseph F., Held, William A., Yu, Li, Krahe, Ralf, Kolitz, Jonathan E., Bloomfield, Clara D., Caligiuri, Michael A., Plass, Christoph

“…Aberrant DNA methylation is believed to be important in tumorigenesis by causing either transcriptional inactivation of genes or chromosomal instability…”
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Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations by Dorrance, Adrienne M, Liu, Shujun, Yuan, Weifeng, Becknell, Brian, Arnoczky, Kristy J, Guimond, Martin, Strout, Matthew P, Feng, Lan, Nakamura, Tatsuya, Yu, Li, Rush, Laura J, Weinstein, Michael, Leone, Gustavo, Wu, Lizhao, Ferketich, Amy, Whitman, Susan P, Marcucci, Guido, Caligiuri, Michael A

“…We previously identified a rearrangement of mixed-lineage leukemia (MLL) gene (also known as ALL-1, HRX, and HTRX1), consisting of an in-frame partial tandem…”
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Gene amplification in PNETs/medulloblastomas: mapping of a novel amplified gene within the MYCN amplicon by Frühwald, Michael C, O'Dorisio, M Sue, Rush, Laura J, Reiter, Jill L, Smiraglia, Dominic J, Wenger, Gail, Costello, Joseph F, White, Peter S, Krahe, Ralf, Brodeur, Garrett M, Plass, Christoph

“…OBJECTIVES The pathological entity of primitive neuroectodermal tumour/medulloblastoma (PNET/MB) comprises a very heterogeneous group of neoplasms on a…”
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Aberrant CpG-island methylation has non-random and tumour-type-specific patterns by Costello, Joseph F, Plass, Christoph, Frühwald, Michael C, Smiraglia, Dominic J, Rush, Laura J, Robertson, Gavin P, Gao, Xin, Wright, Fred A, Feramisco, Jamison D, Peltomäki, Päivi, Lang, James C, Schuller, David E, Yu, Li, Bloomfield, Clara D, Caligiuri, Michael A, Yates, Allan, Nishikawa, Ryo, Su Huang, H.-J, Petrelli, Nicholas J, Zhang, Xueli, O 'Dorisio, M. S, Held, William A, Cavenee, Webster K

“…CpG islands frequently contain gene promoters or exons and are usually unmethylated in normal cells. Methylation of CpG islands is associated with delayed…”
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Malignant Pilomatricoma in 3 Dogs by Carroll, E. E., Fossey, S. L., Mangus, L. M., Carsillo, M. E., Rush, L. J., McLeod, C. G., Johnson, T. O.

“…Malignant pilomatricoma, also known as pilomatrix carcinoma and calcifying epitheliocarcinoma (in the human literature), has been considered a rare neoplasm of…”
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ACE inhibitor related angioedema: a case report and brief review by Boudi FB, Rush JL, Farsar C, Chan CS

“…We present a case report of angiotensin converting enzyme (ACE) inhibitor angioedema successfully treated with icatibant (Firazyr®). The pathophysiology and…”
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Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies by SMIRAGLLA, Dominic J, RUSH, Laura J, CALIGIURI, Michael A, PLASS, Christoph, FRÜHWALD, Michael C, DAI, Zunyan, HELD, William A, COSTELLO, Joseph F, LANG, James C, ENG, Charis, BIN LI, WRIGHT, Fred A

“…Cancer cell lines are widely used in many types of cancer research, including studies aimed at understanding DNA hypermethylation of gene promoters in cancer…”
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A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes by Dai, Zunyan, Zhu, Wei-Guo, Morrison, Carl D., Brena, Romulo M., Smiraglia, Dominic J., Raval, Aparna, Wu, Yue-Zhong, Rush, Laura J., Ross, Patrick, Molina, Julian R., Otterson, Gregory A., Plass, Christoph

“…Amplification of oncogenes is an important mechanism that can cause gene overexpression and contributes to tumor development. The identification of amplified…”
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Restriction landmark genomic scanning for DNA methylation in cancer: past, present, and future applications by Rush, Laura J, Plass, Christoph

“…The field of molecular biology was revolutionized by the advent of gel electrophoresis. Restriction landmark genomic scanning (RLGS) is a type of…”
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Immunoglobulin Crystals in Reactive Plasma Cells in a Dog by Zimmerman, B, Yamaguchi, M.I, Rush, L.J

“…Intracellular crystalline deposits of immunoglobulin are occasionally seen in human B-cell lymphoproliferative disorders such as multiple myeloma, chronic…”
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BAALC, The Human Member of a Novel Mammalian Neuroectoderm Gene Lineage, is Implicated in Hematopoiesis and Acute Leukemia by Tanner, Stephan M., Austin, Jamie L., Leone, Gustavo, Rush, Laura J., Plass, Christoph, Heinonen, Kristiina, Mrózek, Krzysztof, Sill, Heinz, Knuutila, Sakari, Kolitz, Jonathan E., Archer, Kellie J., Caligiuri, Michael A., Bloomfield, Clara D., de la Chapelle, Albert

“…The molecular basis of human leukemia is heterogeneous. Cytogenetic findings are increasingly associated with molecular abnormalities, some of which are being…”
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Quantification of plasma DNA as a prognostic indicator in canine lymphoid neoplasia by Schaefer, D. M. W., Forman, M. A., Kisseberth, W. C., Lehman, A. M., Kelbick, N. T., Harper, P., Rush, L. J.

“…Dogs have a similar incidence of spontaneous cancers as people, and a noninvasive test to monitor disease status in dogs would be of great value. Humans with…”
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Veterinary Pathology and Peer Review by Cantor, G. H., Caswell, J. L., Crissman, J. W., Gillette, D. M., Gunson, D. E., Hogenesch, H., Kiupel, M., Mense, M. G., Miller, M. A., Rush, L. J., St. Leger, J. A., Schoeb, T. R., Sellers, R. S., Sills, R. C., Swayne, D. E., Thomas, H. C., Ward, J. M., Alden, C. L.

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Global Methylation Profiling of Lung Cancer Identifies Novel Methylated Genes by Dai, Zunyan, Lakshmanan, Romola R., Zhu, Wei-Guo, Smiraglia, Dominic J., Rush, Laura J., Frühwald, Michael C., Brena, Romulo M., Li, Bin, Wright, Fred A., Ross, Patrick, Otterson, Gregory A., Plass, Christoph

“…Epigenetic changes, including DNA methylation, are a common finding in cancer. In lung cancers methylation of cytosine residues may affect tumor initiation and…”
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Aberrant hypermethylation of the major breakpoint cluster region in 17p11.2 in medulloblastomas but not supratentorial PNETs by Frühwald, Michael C., O'Dorisio, M. Sue, Dai, Zunyan, Rush, Laura J., Krahe, Ralf, Smiraglia, Dominic J., Pietsch, Torsten, Elsea, Sarah H., Plass, Christoph

“…Deletions of 17p have been consistently reported in up to 50% of medulloblastomas (MBs), and the major breakpoint interval has been localized to chromosome…”
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An AscI boundary library for the studies of genetic and epigenetic alterations in CpG islands by Dai, Zunyan, Weichenhan, Dieter, Wu, Yue-Zhong, Hall, Julia L, Rush, Laura J, Smith, Laura T, Raval, Aparna, Yu, Li, Kroll, Daniela, Muehlisch, Joerg, Frühwald, Michael C, de Jong, Pieter, Catanese, Joe, Davuluri, Ramana V, Smiraglia, Dominic J, Plass, Christoph

“…Knudson's two-hit hypothesis postulates that genetic alterations in both alleles are required for the inactivation of tumor-suppressor genes. Genetic…”
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