Search Results - "RUO XU"

Lipid-protein interactions modulate the conformational equilibrium of a potassium channel by Gu, Ruo-Xu, de Groot, Bert L.

“…Cell membranes actively participate in the regulation of protein structure and function. In this work, we conduct molecular dynamics simulations to investigate…”
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Phase Separation in Atomistic Simulations of Model Membranes by Gu, Ruo-Xu, Baoukina, Svetlana, Tieleman, D. Peter

“…Understanding the lateral organization in plasma membranes remains an open problem despite a large body of research. Model membranes with coexisting…”
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Single-cell landscape of immunological responses in patients with COVID-19 by Zhang, Ji-Yuan, Wang, Xiang-Ming, Xing, Xudong, Xu, Zhe, Zhang, Chao, Song, Jin-Wen, Fan, Xing, Xia, Peng, Fu, Jun-Liang, Wang, Si-Yu, Xu, Ruo-Nan, Dai, Xiao-Peng, Shi, Lei, Huang, Lei, Jiang, Tian-Jun, Shi, Ming, Zhang, Yuxia, Zumla, Alimuddin, Maeurer, Markus, Bai, Fan, Wang, Fu-Sheng

“…In coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the relationship between disease…”
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Immunological and inflammatory profiles in mild and severe cases of COVID-19 by Song, Jin-Wen, Zhang, Chao, Fan, Xing, Meng, Fan-Ping, Xu, Zhe, Xia, Peng, Cao, Wen-Jing, Yang, Tao, Dai, Xiao-Peng, Wang, Si-Yu, Xu, Ruo-Nan, Jiang, Tian-Jun, Li, Wen-Gang, Zhang, Da-Wei, Zhao, Peng, Shi, Ming, Agrati, Chiara, Ippolito, Giuseppe, Maeurer, Markus, Zumla, Alimuddin, Wang, Fu-Sheng, Zhang, Ji-Yuan

“…COVID-19 is associated with 5.1% mortality. Although the virological, epidemiological, clinical, and management outcome features of COVID-19 patients have been…”
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Visualization of the mechanosensitive ion channel MscS under membrane tension by Zhang, Yixiao, Daday, Csaba, Gu, Ruo-Xu, Cox, Charles D., Martinac, Boris, de Groot, Bert L., Walz, Thomas

“…Mechanosensitive channels sense mechanical forces in cell membranes and underlie many biological sensing processes 1 – 3 . However, how exactly they sense…”
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Cholesterol Flip-Flop in Heterogeneous Membranes by Gu, Ruo-Xu, Baoukina, Svetlana, Tieleman, D. Peter

“…Cholesterol is the most abundant molecule in the plasma membrane of mammals. Its distribution across the two membrane leaflets is critical for understanding…”
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Central cavity dehydration as a gating mechanism of potassium channels by Gu, Ruo-Xu, de Groot, Bert L.

“…The hydrophobic gating model, in which ion permeation is inhibited by the hydrophobicity, rather than a physical occlusion of the nanopore, functions in…”
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Single-cell RNA sequencing reveals intrahepatic and peripheral immune characteristics related to disease phases in HBV-infected patients by Zhang, Chao, Li, Jiesheng, Cheng, Yongqian, Meng, Fanping, Song, Jin-Wen, Fan, Xing, Fan, Hongtao, Li, Jing, Fu, Yu-Long, Zhou, Ming-Ju, Hu, Wei, Wang, Si-Yu, Fu, Yuan-Jie, Zhang, Ji-Yuan, Xu, Ruo-Nan, Shi, Ming, Hu, Xueda, Zhang, Zemin, Ren, Xianwen, Wang, Fu-Sheng

“…A comprehensive immune landscape for HBV infection is pivotal to achieve HBV cure. We performed single-cell RNA sequencing of 2 43 000 cells from 46 paired…”
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Effect of polyethylene microplastics on oxidative stress and histopathology damages in Litopenaeus vannamei by Hsieh, Shu-Ling, Wu, Yi-Chen, Xu, Ruo-Qi, Chen, Ya-Ting, Chen, Chiu-Wen, Singhania, Reeta Rani, Dong, Cheng-Di

“…There has been a significant increase in the microplastic (MP) polluting the ocean in recent time which is regarded as toxic for living organisms. In this…”
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Ganglioside-Lipid and Ganglioside-Protein Interactions Revealed by Coarse-Grained and Atomistic Molecular Dynamics Simulations by Gu, Ruo-Xu, Ingólfsson, Helgi I, de Vries, Alex H, Marrink, Siewert J, Tieleman, D. Peter

“…Gangliosides are glycolipids in which an oligosaccharide headgroup containing one or more sialic acids is connected to a ceramide. Gangliosides reside in the…”
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Mesenchymal stem cell therapy in decompensated liver cirrhosis: a long-term follow-up analysis of the randomized controlled clinical trial by Shi, Ming, Li, Yuan-Yuan, Xu, Ruo-Nan, Meng, Fan-Ping, Yu, Shuang-Jie, Fu, Jun-Liang, Hu, Jin-Hua, Li, Jing-Xin, Wang, Li-Feng, Jin, Lei, Wang, Fu-Sheng

“…Background Mesenchymal stem cell (MSC) infusion was reported to improve liver function in patients with decompensated liver cirrhosis (DLC); however, whether…”
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Proteomics-based vaccine targets annotation and design of subunit and mRNA-based vaccines for Monkeypox virus (MPXV) against the recent outbreak by Jin, Yifan, Fayyaz, Addeela, Liaqat, Ayesha, Khan, Abbas, Alshammari, Abdulrahman, Wang, Yanjing, Gu, Ruo-Xu, Wei, Dong-Qing

“…Monkeypox Virus (MPXV) is a growing public health threat with increasing cases and fatalities globally. To date, no specific vaccine or small molecule…”
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Inhibition of β‑Amyloid Channels with a Drug Candidate wgx-50 Revealed by Molecular Dynamics Simulations by Hou, Shuang, Gu, Ruo-Xu, Wei, Dong-Qing

“…Destabilization of cellular ionic homeostasis by toxic β-amyloid (Aβ) channels/barrels, which is a pathogenic mechanism for Alzheimer’s disease (AD), is…”
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Early Aggregation Mechanism of SOD128–38 Based on Force Field Parameter of 5‑Cyano-Tryptophan by Rahman, Mueed Ur, Bano, Saira, Hong, Xiaokun, Gu, Ruo-Xu, Chen, Hai-Feng

“…The aggregation of superoxide dismutase 1 (SOD1) results in amyloid deposition and is involved in familial amyotrophic lateral sclerosis, a fatal motor neuron…”
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Interleukin‐17–producing CD4+ T cells increase with severity of liver damage in patients with chronic hepatitis B by Zhang, Ji‐Yuan, Zhang, Zheng, Lin, Fang, Zou, Zheng‐Sheng, Xu, Ruo‐Nan, Jin, Lei, Fu, Jun‐Liang, Shi, Feng, Shi, Ming, Wang, Hui‐Fen, Wang, Fu‐Sheng

“…Interleukin‐17 (IL‐17)‐producing CD4+ T cells (Th17)‐mediated immune response has been demonstrated to play a critical role in inflammation‐associated disease;…”
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Structure of Transmembrane Helix 8 and Possible Membrane Defects in CFTR by Corradi, Valentina, Gu, Ruo-Xu, Vergani, Paola, Tieleman, D. Peter

“…The cystic fibrosis transmembrane conductance regulator (CFTR) is an ion channel that regulates the flow of anions across epithelia. Mutations in CFTR cause…”
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Development and Application of Computational Methods in Biology and Medicine by Huang, Zunnan, Gu, Ruo-Xu

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Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells by Liao, Hsin-Kai, Gu, Ying, Diaz, Arturo, Marlett, John, Takahashi, Yuta, Li, Mo, Suzuki, Keiichiro, Xu, Ruo, Hishida, Tomoaki, Chang, Chan-Jung, Esteban, Concepcion Rodriguez, Young, John, Belmonte, Juan Carlos Izpisua

“…To combat hostile viruses, bacteria and archaea have evolved a unique antiviral defense system composed of clustered regularly interspaced short palindromic…”
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Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke by Xia, Geng-Hong, You, Chao, Gao, Xu-Xuan, Zeng, Xiu-Li, Zhu, Jia-Jia, Xu, Kai-Yu, Tan, Chu-Hong, Xu, Ruo-Ting, Wu, Qi-Heng, Zhou, Hong-Wei, He, Yan, Yin, Jia

“…Significant dysbiosis occurs in the gut microbiome of stroke patients. Condensing these broad, complex changes into one index would greatly facilitate the…”
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A Miniaturized C-B and SIW Bandpass Filter based on LTCC by Tang, Wei, Xu, Ruo-Feng, Zhao, Lei

“…In this paper, a miniaturized bandpass filter based on low temperature co-fired ceramic (LTCC) technology is proposed. The miniaturization is achieved by two…”
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