Search Results - "RUMACK, B. H"

4-Methylpyrazole protects against acetaminophen hepatotoxicity in mice and in primary human hepatocytes by Akakpo, J Y, Ramachandran, A, Kandel, S E, Ni, H M, Kumer, S C, Rumack, B H, Jaeschke, H

“…Liver injury due to acetaminophen (APAP) overdose is the major cause of acute liver failure in the United States. While treatment with N-acetylcysteine is the…”
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A single-arm clinical trial of a 48-hour intravenous N-acetylcysteine protocol for treatment of acetaminophen poisoning by Heard, K., Rumack, B. H., Green, J. L., Bucher-Bartelson, B., Heard, S., Bronstein, A. C., Dart, R. C.

“…Abstract Introduction. Acetylcysteine prevents hepatic injury when administered soon after acetaminophen overdose. The most commonly used treatment protocols…”
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Acetaminophen overdose? A quick answer by Rumack, Barry H.

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Hydroxocobalamin as a cyanide antidote: safety, efficacy and pharmacokinetics in heavily smoking normal volunteers by Forsyth, J C, Mueller, P D, Becker, C E, Osterloh, J, Benowitz, N L, Rumack, B H, Hall, A H

“…The safety, efficacy and pharmacokinetic parameters of 5 g of hydroxocobalamin given intravenously, alone or in combination with 12.5 g of sodium thiosulfate,…”
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Acetaminophen overdose in children and adolescents by Rumack, B H

“…Ingestion of acetaminophen by young children and adolescents is common. Most children under the age of 6 who have ingested pediatric products can be safely…”
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Management of acutely poisoned patients without gastric emptying by Kulig, K, Bar-Or, D, Cantrill, S V, Rosen, P, Rumack, B H

“…During an 18-month period, 592 acute oral drug overdose patients were studied prospectively in a controlled, randomized fashion to determine the efficacy of…”
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Fluoride ingestion in children : a review of 87 cases by AUGENSTEIN, W. L, SPOERKE, D. G, KULIG, K. W, HALL, A. H, HALL, P. K, RIGGS, B. S, EL SAADI, M, RUMACK, B. H

“…All cases of fluoride ingestion in children younger than 12 years old reported to the Rocky Mountain Poison Center between January 1 and December 31, 1986,…”
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Acetaminophen overdose: a 48-hour intravenous N-acetylcysteine treatment protocol by Smilkstein, M J, Bronstein, A C, Linden, C, Augenstein, W L, Kulig, K W, Rumack, B H

“…To determine the safety and efficacy of a 48-hour IV N-acetylcysteine (IV NAC) treatment protocol for acute acetaminophen overdose. Nonrandomized trial open to…”
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Acetaminophen Hepatotoxicity: The First 35 Years by Rumack, Barry H.

“…The acetaminophen nomogram including its uses and limitations is discussed as well as the development of the N-acetylcysteine protocol. While it has taken many…”
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Acetaminophen poisoning and toxicity by Rumack, B H, Matthew, H

“…Acetaminophen (paracetamol in British literature) is a metabolite of phenacetin which has become increasingly popular as a substitute for salicylates.1 The…”
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Cimetidine as adjunctive treatment for acetaminophen overdose by Burkhart, K K, Janco, N, Kulig, K W, Rumack, B H

“…The aim of this study was to determine if cimetidine in addition to N-acetylcysteine and standard supportive care provide additional hepatoprotection following…”
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Battery ingestions by RUMACK, C. M, RUMACK, B. H

“…The proliferation of battery-operated devices has provided a new source of hazards for children. "Button batteries" are small cells used in hearing aids,…”
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Acute acetaminophen overdose during pregnancy by Riggs, B S, Bronstein, A C, Kulig, K, Archer, P G, Rumack, B H

“…During a nationwide acetaminophen overdose study conducted at the Rocky Mountain Poison and Drug Center from 1976-1985, 113 patients entered into the study…”
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Superwarfarin poisoning in children: a prospective study by SMOLINSKE, S. C, SCHERGER, D. L, KEARNS, P. S, WRUK, K. M, KULIG, K. W, RUMACK, B. H

“…This prospective study was undertaken to determine the incidence, severity, time of onset, and duration of coagulopathy in children following accidental…”
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Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985) by Smilkstein, M J, Knapp, G L, Kulig, K W, Rumack, B H

“…During the investigational use of oral N-acetylcysteine as an antidote for poisoning with acetaminophen, 11,195 cases of suspected acetaminophen overdose were…”
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Role of free radicals in toxic hepatic injury. II. Are free radicals the cause of toxin-induced liver injury? by Brent, J A, Rumack, B H

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Aspirin versus acetaminophen: a comparative view by Rumack, B H

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Clinical safety of high oral doses of acetylcysteine by Miller, L F, Rumack, B H

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Ibuprofen overdose: 126 cases by Hall, A H, Smolinske, S C, Conrad, F L, Wruk, K M, Kulig, K W, Dwelle, T L, Rumack, B H

“…In this study of ibuprofen overdose, symptoms developed in 19% of patients (24 of 126)--in 7% of children (6 of 88) and in 47% of adults (18 of 38). Central…”
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Hemorrhagic pancreatitis associated with acetaminophen overdose by Caldarola, V, Hassett, J M, Hall, A H, Bronstein, A B, Kulig, K W, Rumack, B H

“…A 19-yr-old man ingested 25 g of acetaminophen in a suicide attempt. Twenty-one hours after the ingestion the plasma acetaminophen level was potentially…”
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