Search Results - "RULEY, H. E"

Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death by Hicks, Geoffrey G, Singh, Nagendra, Nashabi, Abudi, Mai, Sabine, Bozek, Gracjan, Klewes, Ludger, Arapovic, Djula, White, Erica K, Koury, Mark J, Oltz, Eugene M, Van Kaer, Luc, Ruley, H. E

“…The gene FUS (also known as TLS (for translocated in liposarcoma) and hnRNP P2) is translocated with the gene encoding the transcription factor ERG-1 in human…”
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Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis by LOWE, S. W, RULEY, H. E

“…Oncogenic transformation by human adenoviruses requires early regions 1A and 1B (E1A and E1B) and provides a model of multistep carcinogenesis. This study…”
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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents by Lowe, S W, Ruley, H E, Jacks, T, Housman, D E

“…Although the primary cellular targets of many anticancer agents have been identified, less is known about the processes leading to the selective cell death of…”
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p53 Status and the Efficacy of Cancer Therapy in Vivo by Lowe, Scott W., Bodis, Stephan, McClatchey, Andrea, Remington, Lee, Ruley, H. Earl, Fisher, David E., Housman, David E., Jacks, Tyler

“…The therapeutic responsiveness of genetically defined tumors expressing or devoid of the p53 tumor suppressor gene was compared in immunocompromised mice…”
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Abrogation of Oncogene-Associated Apoptosis Allows Transformation of p53- Deficient Cells by Lowe, Scott W., Jacks, Tyler, Housman, David E., Ruley, H. Earl

“…p53-deficient mouse embryonic fibroblasts were used to establish a direct mechanism of tumor suppression by p53 involving the destruction of…”
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PUM2, a novel murine Puf protein, and its consensus RNA-binding site by WHITE, ERICA K., MOORE-JARRETT, TRACY, RULEY, H. EARL

“…Members of the Puf family of RNA-binding proteins from Drosophila, Caenorhabditis elegans, and Dictyostelium are known to function as translational repressors…”
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Two regions of the adenovirus early region 1A proteins are required for transformation by WHYTE, P, RULEY, H. E, ED HARLOW

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Transcription from the stromelysin promoter is induced by interleukin-1 and repressed by dexamethasone by Frisch, SM, Ruley, HE

“…The stromelysin gene encodes a potent tissue-degrading proteinase whose activity is important in tissue-remoldeling processes such as wound healing, the…”
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Functional genomics in mice by tagged sequence mutagenesis by Hicks, Geoffrey G, Shi, Er-gang, Li, Xuan-Mei, Li, Chun-Hua, Pawlak, Maciej, Ruley, H. Earl

“…Most mammalian genes will soon be characterized as cDNA sequences with little information about their function. To utilize this sequence information for…”
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A murine homolog of the yeast RNA1 gene is required for postimplantation development by DEGREGORI, J, RUSS, A, VON MELCHNER, H, RAYBURN, H, PRASHANT PRIYARANJAN, JANKINS, N. A, COPELAND, N. G, RULEY, H. E

“…A gene has been characterized that is required for postimplantation mouse development. The gene, designated fug1, was disrupted in embryonic stem cells by the…”
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Rescue of Cells from ras Oncogene-Induced Growth Arrest by a Second, Complementing, Oncogene by Hirakawa, Tadashi, Ruley, H. Earl

“…Established REF52 cells (rat embryo fibroblasts) completely resist stable transformation by ras oncogenes, and simian virus 40 large tumor (T) antigen…”
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Apoptosis in erythroid progenitors deprived of erythropoietin occurs during the G1 and S phases of the cell cycle without growth arrest or stabilization of wild-type p53 by KELLEY, L. L, GREEN, W. F, HICKS, G. G, BONDURANT, M. C, KOURY, M. J, RULEY, H. E

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Arginine N-Methyltransferase 1 Is Required for Early Postimplantation Mouse Development, but Cells Deficient in the Enzyme Are Viable by Pawlak, Maciej R., Scherer, Christina A., Chen, Jin, Roshon, Michael J., Ruley, H. Earl

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Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells by Zerler, B, Moran, B, Maruyama, K, Moomaw, J, Grodzicker, T, Ruley, H E

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Identification of cellular promoters by using a retrovirus promoter trap by VON MELCHNER, H, RYLEY, H. E

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Selective Targeting of Gene Products with the Megakaryocyte Platelet Factor 4 Promoter by Ravid, Katya, Beeler, David L., Rabin, Michael S., Ruley, H. Earl, Rosenberg, Robert D.

“…We have used the 1.1 kilobases of the 5' upstream region of the platelet factor four (PF4) gene coupled to the prokaryotic β-galactosidase gene to generate two…”
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Functional genomics of the murine immune system by Ruley, H E

“…The mouse and human genome sequences provide new opportunities to characterize mammalian gene functions on a genome-wide level. Toward this end, we have…”
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Fluorescence-Activated Sorting of Totipotent Embryonic Stem Cells Expressing Developmentally Regulated lacZ Fusion Genes by Reddy, Sita, Rayburn, Helen, von Melchner, Harald, Ruley, H. Earl

“…Murine embryonic stem (ES) cells were infected with a retrovirus promoter trap vector, and clones expressing lacZ fusion genes (LacZ+) were isolated by…”
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Selective disruption of genes expressed in totipotent embryonal stem cells by VON MELCHNER, H, DEGREGORI, J. V, RAYBURN, H, REDDY, S, FRIEDEL, C, RULEY, H. E

“…Two retrovirus promoter trap vectors (U3His and U3Neo) have been used to disrupt genes expressed in totipotent murine embryonal stem (ES) cells. Selection in…”
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Isolation of Cellular Promoters by Using a Retrovirus Promoter Trap by von Melchner, Harald, Reddy, Sita, Ruley, H. Earl

“…A retrovirus vector has been used to isolate transcriptional promoters from mammalian cells. The virus contains a selectable gene encoding histidinol…”
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