Search Results - "RUEHLMANN, J. Michael"

Long-term safety and effectiveness of etanercept in JIA: an 18-year experience from the BiKeR registry by Armaroli, Giulia, Klein, Ariane, Ganser, Gerd, Ruehlmann, Michael J, Dressler, Frank, Hospach, Anton, Minden, Kirsten, Trauzeddel, Ralf, Foeldvari, Ivan, Kuemmerle-Deschner, Jasmin, Weller-Heinemann, Frank, Urban, Andreas, Horneff, Gerd

“…Background At present, etanercept represents the most commonly prescribed biologic agent for juvenile idiopathic arthritis (JIA) treatment. Children and…”
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Efficacy and Safety of Etanercept Biosimilars Compared With the Originator for Treatment of Juvenile Arthritis: A Prospective Observational Study by Thiele, Franz, Klein, Ariane, Hospach, Anton, Windschall, Daniel, Mrusek, Sonja, Ruehlmann, J. Michael, Horneff, Gerd

“…Objective Analysis of etanercept biosimilars in pediatric patients with juvenile idiopathic arthritis (JIA) in comparison with the etanercept originator in…”
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An Autologous Oral DNA Vaccine Protects against Murine Melanoma by Xiang, Rong, Lode, Holger N., Chao, Ta-Hsiang, Ruehlmann, J. Michael, Dolman, Carrie S., Rodriguez, Fernando, Whitton, J. Lindsay, Overwijk, Willem W., Restifo, Nicholas P., Reisfeld, Ralph A.

“…We demonstrated that peripheral T cell tolerance toward murine melanoma self-antigens gp 100 and TRP-2 can be broken by an autologous oral DNA vaccine…”
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Immunotherapy with a posttranscriptionally modified DNA vaccine induces complete protection against metastatic neuroblastoma by Pertl, Ursula, Wodrich, Harald, Ruehlmann, J. Michael, Gillies, Stephen D., Lode, Holger N., Reisfeld, Ralph A.

“…The successful induction of a T-cell–mediated tumor-protective immunity against poorly immunogenic malignancies remains a major challenge for cancer…”
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Protective Immunity against Human Carcinoembryonic Antigen (CEA) Induced by an Oral DNA Vaccine in CEA-transgenic Mice by RONG XIANG, SILLETTI, Steve, LODE, Holger N, DOLMAN, Carrie S, RUEHLMANN, J. Michael, NIETHAMMER, Andreas G, PERTL, Ursula, GILLIES, Stephen D, PRIMUS, F. James, REISFELD, Ralph A

“…Peripheral T-cell tolerance toward human carcinoembryonic self-antigen (CEA) was broken in CEA-transgenic C57BL/6J mice by an oral CEA-based DNA vaccine. This…”
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A Dual-Function DNA Vaccine Encoding Carcinoembryonic Antigen and CD40 Ligand Trimer Induces T Cell-Mediated Protective Immunity Against Colon Cancer in Carcinoembryonic Antigen-Transgenic Mice by Xiang, Rong, Primus, F. James, Ruehlmann, J. Michael, Niethammer, Andreas G, Silletti, Steve, Lode, Holger N, Dolman, Carrie S, Gillies, Stephen D, Reisfeld, Ralph A

“…A carcinoembryonic Ag (CEA)-based DNA vaccine encoding both CEA and CD40 ligand trimer achieved effective tumor-protective immunity against murine colon…”
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MIG (CXCL9) chemokine gene therapy combines with antibody-cytokine fusion protein to suppress growth and dissemination of murine colon carcinoma by RUEHLMANN, J. Michael, RONG XIANG, NIETHAMMER, Andreas G, YI BA, PERTL, Ursula, DOLMAN, Carrie S, GILLIES, Stephen D, REISFELD, Ralph A

“…The induction of a CTL response capable of eradicating disseminated tumor metastases and the establishment of a persistent tumor-protective immunity remain…”
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An oral DNA vaccine against human carcinoembryonic antigen (CEA) prevents growth and dissemination of Lewis lung carcinoma in CEA transgenic mice by Niethammer, Andreas G, Primus, F.James, Xiang, Rong, Dolman, Carrie S, Ruehlmann, J.Michael, Ba, Yi, Gillies, Stephen D, Reisfeld, Ralph A

“…A DNA vaccine encoding human carcinoembryonic antigen (CEA) broke peripheral T-cell tolerance toward this tumor self-antigen expressed by Lewis lung carcinoma…”
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Targeted interleukin 2 therapy enhances protective immunity induced by an autologous oral DNA vaccine against murine melanoma by NIETHAMMER, Andreas G, RONG XIANG, RUEHLMANN, J. Michael, LODE, Holger N, DOLMAN, Carrie S, GILLIES, Stephen D, REISFELD, Ralph A

“…We demonstrate that a mouse-human chimeric anti-ganglioside GD2-interleukin (IL)-2 fusion protein (ch14.18-IL2) substantially amplifies tumor-protective…”
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