Search Results - "RUDZKI, Z"

Two Cases of γ-Heavy Chain Disease and a Review of the Literature by Ramasamy, I., Rudzki, Z.

“…Gamma heavy chain disease (γ-HCD) is a rare lymphoproliferative disorder characterised by the production of a truncated immunoglobulin heavy chain. Fewer than…”
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MYC/BCL6 DOUBLE HIT LYMPHOMA NEGATIVE FOR T(3;8) BCL6::MYC FUSION IS ASSOCIATED WITH INFERIOR SURVIVAL, IN CONTRAST WITH T(3;8) POSITIVE PSEUDO‐DOUBLE HIT LYMPHOMA by Maybury, B. D., James, L., Chadderton, N., Dowds, J., Venkatadasari, I., Riley, J., Qureshi, I., Talbot, G., Giles, H. V., Phillips, N. J., Gonzalez, M. Vega, Rakesh, P., Haslam, A., Davies, D., Moosai, S., Lane, S. A., Shenouda, A., Cherian, G. V., Kaudlay, P. K., Starczynski, J., Rudzki, Z., Chaganti, S.

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Monitoring chronic myeloid leukaemia therapy by real‐time quantitative PCR in blood is a reliable alternative to bone marrow cytogenetics by BRANFORD, S, HUGHES, T. P, RUDZKI, Z

“…We have developed a rapid real‐time quantitative PCR method for measuring BCR‐ABL mRNA levels in peripheral blood in chronic myeloid leukaemia (CML). The…”
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Imatinib produces significantly superior molecular responses compared to interferon alfa plus cytarabine in patients with newly diagnosed chronic myeloid leukemia in chronic phase by BRANFORD, S, RUDZKI, Z, SEYMOUR, J. F, BRADSTOCK, K, JOSKE, D, LYNCH, K, GATHMANN, I, HUGHES, T. P, HARPER, A, GRIGG, A, TAYLOR, K, DURRANT, S, ARTHUR, C, BROWETT, P, SCHWARER, A. P, MA, D

“…We analyzed molecular responses in 55 newly diagnosed chronic-phase chronic myeloid leukemia (CML) patients enrolled in a phase 3 study (the IRIS trial)…”
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A de novo splice donor mutation in the thrombopoietin gene causes hereditary thrombocythemia in a Polish family by Liu, Kun, Kralovics, Robert, Rudzki, Zbigniew, Grabowska, Barbara, Buser, Andreas S, Olcaydu, Damla, Gisslinger, Heinz, Tiedt, Ralph, Frank, Patricia, Okon, Krzysztof, van der Maas, Anthonie P.C, Skoda, Radek C

“…1 Experimental Hematology, Department of Biomedicine, Basel University Hospital, Basel, Switzerland 2 Department of Pathomorphology, Collegium Medicum,…”
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A novel BCR–ABL transcript (e8a2) with the insertion of an inverted sequence of ABL intron 1b in a patient with Philadelphia‐positive chronic myeloid leukaemia by Branford, S., Rudzki, Z., Hughes, T. P.

“…An atypical BCR–ABL transcript in a patient with Philadelphia (Ph)‐positive chronic myeloid leukaemia (CML) was detected using a long polymerase chain reaction…”
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Why we will need to learn new skills to control cancer by Brown, M. P., Buckley, M. F., Rudzki, Z., Olver, I. N.

“…As a society and as specialists involved in the diagnosis and management of cancer, we must begin to find new cost‐effective ways to provide equitable access…”
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Megakaryocytic features useful for the diagnosis of myeloproliferative disorders can be obtained by a novel unsupervised software analysis by Tripodo, C, Valenti, C, Ballarò, B, Rudzki, Z, Tegolo, D, Di Gesù, V, Florena, A M, Franco, V

“…An unsupervised method for megakaryocyte detection and analysis is proposed, in order to validate supplementary tools which can be of help in supporting the…”
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Induction of immune tolerance and suppression of anaphylaxis in a child with haemophilia B by simple plasmapheresis and antigen exposure by Barnes, C., Rudzki, Z., Ekert, H.

“…Anaphylaxis to factor IX (FIX) in patients with haemophilia B is a rare and life‐threatening complication that has been reported to occur in association with…”
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Two Cases of [gamma]-Heavy Chain Disease and a Review of the Literature by Ramasamy, I, Rudzki, Z

“…Gamma heavy chain disease ([gamma]-HCD) is a rare lymphoproliferative disorder characterised by the production of a truncated immunoglobulin heavy chain. Fewer…”
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The relationship between gastric cancer cells circulating in the blood and microsatellite instability positive gastric carcinomas by Czopek, J., Bialas, M., Rudzki, Z., Zazula, M., Pituch‐Noworolska, A., Zembala, M., Popiela, T., Kulig, J., Kolodziejczyk, P., Stachura, J.

“…Background: Cancers characterized by microsatellite instability may be biologically different from their counterparts with stable microsatellite sequences…”
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Preliminary report on pathology of colorectal cancer in Poland in 1995 and 1975 : is it still the same disease? by RUDZKI, Z, STACHURA, J

“…Over past three decades in Poland we have seen a steady increase in the incidence of colorectal cancer. It is unclear whether this phenomenon is associated…”
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A single, large deletion accounts for all the beta-globin gene mutations in twenty families from Sabah (North Borneo), Malaysia. Mutation in brief no. 240. Online by Thong, M K, Rudzki, Z, Hall, J, Tan, J A, Chan, L L, Yap, S F

“…Beta-thalassemia major is one of the commonest genetic disorders in South-East Asia. The spectrum of beta-thalassemia mutations in the various ethnic…”
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Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis by Branford, Susan, Rudzki, Zbigniew, Walsh, Sonya, Parkinson, Ian, Grigg, Andrew, Szer, Jeff, Taylor, Kerry, Herrmann, Richard, Seymour, John F., Arthur, Chris, Joske, David, Lynch, Kevin, Hughes, Tim

“…Imatinib-treated chronic myeloid leukemia (CML) patients with acquired resistance commonly have detectable BCR-ABL kinase domain mutations. It is unclear…”
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Changes in CD44 Expression during Carcinogenesis of the Mouse Colon by Rudzki, Zbigniew, LeDuy, Lam, Jothy, Serge

“…CD44 glycoprotein is the main extracellular receptor for hyaluronic acid. The CD44 gene is composed of 20 exons and encodes a variety of isoforms generated by…”
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High frequency of point mutations clustered within the adenosine triphosphate–binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance by Branford, Susan, Rudzki, Zbigniew, Walsh, Sonya, Grigg, Andrew, Arthur, Chris, Taylor, Kerry, Herrmann, Richard, Lynch, Kevin P., Hughes, Timothy P.

“…Point mutations were found in the adenosine triphosphate (ATP) binding region of BCR/ABL in 12 of 18 patients with chronic myeloid leukemia (CML) or…”
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Frequency of Major Molecular Responses to Imatinib or Interferon Alfa plus Cytarabine in Newly Diagnosed Chronic Myeloid Leukemia by Hughes, Tim P, Kaeda, Jaspal, Branford, Susan, Rudzki, Zbigniew, Hochhaus, Andreas, Hensley, Martee L, Gathmann, Insa, Bolton, Ann E, van Hoomissen, Iris C, Goldman, John M, Radich, Jerald P

“…Measurement of the transcripts of BCR-ABL, the key molecular abnormality in chronic myeloid leukemia (CML), provides an estimate of the burden of leukemic…”
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Heterozygosity of the Haemochromatosis Mutation, C282Y, Does Not Influence Susceptibility to Alcoholic Cirrhosis by ANDREAS FRENZER, ZBIGNIEW RUDZKI, IAN D. NORTON, WENDY J. BUTLER, IAN C. ROBERTS-THOMSON

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Detection of paternally inherited mutations for beta-thalassemia in trophoblast isolated from peripheral maternal blood by Hawes, C S, Suskin, H A, Kalionis, B, Mueller, U W, Casey, G, Hall, J, Rudzki, Z

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Real-time quantitative PCR analysis can be used as a primary screen to identify patients with CML treated with imatinib who have BCR-ABL kinase domain mutations by Branford, Susan, Rudzki, Zbigniew, Parkinson, Ian, Grigg, Andrew, Taylor, Kerry, Seymour, John F., Durrant, Simon, Browett, Peter, Schwarer, Anthony P., Arthur, Chris, Catalano, John, Leahy, Michael F., Filshie, Robin, Bradstock, Kenneth, Herrmann, Richard, Joske, David, Lynch, Kevin, Hughes, Tim

“…Mutations within the BCR-ABL kinase domain in imatinib-treated chronic myeloid leukemia (CML) are the main mechanism of acquired resistance. The early…”
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