Search Results - "RUDOLFSSON, Stina Häggström"

Extratumoral Macrophages Promote Tumor and Vascular Growth in an Orthotopic Rat Prostate Tumor Model by Halin, Sofia, Häggström Rudolfsson, Stina, Van Rooijen, Nico, Bergh, Anders

“…Tumor-associated macrophages are involved in angiogenesis and tumor progression, but their role and specific site of action in prostate cancer remain unknown…”
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Low Levels of Phosphorylated Epidermal Growth Factor Receptor in Nonmalignant and Malignant Prostate Tissue Predict Favorable Outcome in Prostate Cancer Patients by HAMMARSTEN, Peter, KARALIJA, Amar, JOSEFSSON, Andreas, RUDOLFSSON, Stina Häggström, WIKSTRÖM, Pernilla, EGEVAD, Lars, GRANFORS, Torvald, STATTIN, Pär, BERGH, Anders

“…Purpose: To explore if the expression of phosphorylated epidermal growth factor receptor (pEGFR) in nonmalignant and malignant prostate tissue is a potential…”
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Testosterone-stimulated growth of the rat prostate may be driven by tissue hypoxia and hypoxia-inducible factor-1α by Rudolfsson, Stina Häggström, Bergh, Anders

“…Testosterone-stimulated growth of the ventral prostate (VP) in castrated rats is preceded by angiogenesis, but the mechanisms coordinating vascular and tissue…”
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Different vascular endothelial growth factor (VEGF), VEGF‐receptor 1 and ‐2 mRNA expression profiles between clear cell and papillary renal cell carcinoma by LJUNGBERG, BÖRJE J., JACOBSEN, JAN, RUDOLFSSON, STINA HÄGGSTRÖM, LINDH, GUDRUN, GRANKVIST, KJELL, RASMUSON, TORGNY

“…OBJECTIVES To examine vascular endothelial growth factor (VEGF), VEGF‐receptor‐(R)1, and R2 mRNA levels in renal cell carcinoma (RCC), a tumour generally…”
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Decreased pigment epithelium-derived factor is associated with metastatic phenotype in human and rat prostate tumors by HALIN, Sofia, WIKSTRÖM, Pernilla, HÄGGSTRÖM RUDOLFSSON, Stina, STATTIN, Pär, DOLL, Jennifer A, CRAWFORD, Susan E, BERGH, Anders

“…Pigment epithelium-derived factor, a potent angiogenesis inhibitor in the eye, is also expressed in the prostate. Prostate size and angiogenesis is increased…”
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Altered Levels of Angiopoietin 1 and Tie 2 Are Associated with Androgen-Regulated Vascular Regression and Growth in the Ventral Prostate in Adult Mice and Rats by Johansson, Anna, Rudolfsson, Stina Häggström, Wikström, Pernilla, Bergh, Anders

“…The involution of the rat ventral prostate gland after castration could be caused by primary changes in the vasculature. To explore the mechanisms, we studied…”
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Hypoxia drives prostate tumour progression and impairs the effectiveness of therapy, but can also promote cell death and serve as a therapeutic target by Rudolfsson, Stina Häggström, Bergh, Anders

“…Hypoxia is common in prostate tumours, promoting tumour progression and impairing treatment responses. Hypoxia stimulates angiogenesis but blood vessels formed…”
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Targeting castration‐induced tumour hypoxia enhances the acute effects of castration therapy in a rat prostate cancer model by Johansson, Anna, Rudolfsson, Stina Häggström, Kilter, Sigrid, Bergh, Anders

“…What’s known on the subject? and What does the study add? Castration therapy has rather modest effects on cell death in tumours but can be enhanced by other…”
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Pigment Epithelium-Derived Factor Stimulates Tumor Macrophage Recruitment and Is Downregulated by the Prostate Tumor Microenvironment by Halin, Sofia, Rudolfsson, Stina Häggström, Doll, Jennifer A., Crawford, Susan E., Wikström, Pernilla, Bergh, Anders

“…Pigment epithelium-derived factor (PEDF) is a potent inhibitor of angiogenesis but whether it has additional effects on the tumor microenvironment is largely…”
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Inhibitory Effects of Castration in an Orthotopic Model of Androgen-Independent Prostate Cancer Can Be Mimicked and Enhanced by Angiogenesis Inhibition by Hammarsten, Peter, Halin, Sofia, Wikstöm, Pernilla, Henriksson, Roger, Rudolfsson, Stina Häggström, Bergh, Anders

“…Purpose: Today, the most important treatment of advanced prostate cancer is castration; unfortunately, however, the long-term effect of this therapy is…”
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Inhibition of the epidermal growth factor receptor enhances castration-induced prostate involution and reduces testosterone-stimulated prostate growth in adult rats by Hammarsten, Peter, Rudolfsson, Stina Häggström, Henriksson, Roger, Wikström, Pernilla, Bergh, Anders

“…BACKGROUND The epidermal growth factor receptor (EGFR) mediates regulatory signals in the normal prostate, but the functional importance of this is unclear…”
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A stroma targeted therapy enhances castration effects in a transplantable rat prostate cancer model by Johansson, Anna, Jones, Jonathan, Pietras, Kristian, Kilter, Sigrid, Skytt, Åsa, Rudolfsson, Stina Häggström, Bergh, Anders

“…BACKGROUND Castration results in a major involution of the normal prostate gland. This process is initiated by effects in the prostate stroma and vasculature…”
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Localized Expression of Angiopoietin 1 and 2 May Explain Unique Characteristics of the Rat Testicular Microvasculature by RUDOLFSSON, Stina Häggström, JOHANSSON, Anna, LISSBRANT, Ingela Franck, WIKSTRÖM, Pernilla, BERGH, Anders

“…The testicular vasculature is unique in several ways. The unfenestrated endothelial cells constitute one part of the blood-testis barrier, and testicular…”
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Hormonal Regulation and Functional Role of Vascular Endothelial Growth Factor A in the Rat Testis1 by Rudolfsson, Stina Häggström, Wikström, Pernilla, Jonsson, Andreas, Collin, Ola, Bergh, Anders

“…Vascular endothelial cell growth factor (VEGF-A) is synthesized in the testis but its role and regulation in this organ have not been examined. VEGF and its…”
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Extratumoral Macrophages Promote Tumor and Vascular Growth in an Orthotopic Rat Prostate Tumor Model1 by Halin, Sofia, Rudolfsson, Stina Häggström, Van Rooijen, Nico, Bergh, Anders

“…Tumor-associated macrophages are involved in angiogenesis and tumor progression, but their role and specific site of action in prostate cancer remain unknown…”
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Pigment Epithelium-Derived Factor Stimulates Tumor Macrophage Recruitment and Is Downregulated by the Prostate Tumor Microenvironment1 by Halin, Sofia, Stina Häggström, Rudolfsson, Doll, Jennifer A, Crawford, Susan E, Wikström, Pernilla, Bergh, Anders

“…Pigment epithelium-derived factor (PEDF) is a potent inhibitor of angiogenesis but whether it has additional effects on the tumor microenvironment is largely…”
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Testosterone-stimulated growth of the rat prostate may be driven by tissue hypoxia and hypoxia-inducible factor-1alpha by Rudolfsson, Stina Häggström, Bergh, Anders

“…Testosterone-stimulated growth of the ventral prostate (VP) in castrated rats is preceded by angiogenesis, but the mechanisms coordinating vascular and tissue…”
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Neutralizing VEGF bioactivity with a soluble chimeric VEGF-receptor protein flt(1-3)IgG inhibits testosterone-stimulated prostate growth in castrated mice by Lissbrant, Ingela Franck, Hammarsten, Peter, Lissbrant, Erik, Ferrara, Napoleone, Rudolfsson, Stina Häggström, Bergh, Anders

“…BACKGROUND Recent studies show that testosterone‐stimulated growth of the glandular tissue in the ventral prostate in adult castrated rats is preceded by…”
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Inhibitory effects of castration in an orthotopic model of androgen-lndependent prostate cancer can be mimicked and enhanced by angiogenesis inhibition by HAMMARSTEN, Peter, HALIN, Sofia, WIKSTÖM, Pernilla, HENRIKSSON, Roger, RUDOLFSSON, Stina Häggström, BERGH, Anders

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Inhibition of the epidermal growth factor receptor enhances castration-induced prostate involution and reducestestosterone-stimulated prostate growth in adult rats by HAMMARSTEN, Peter, RUDOLFSSON, Stina Häggström, HENRIKSSON, Roger, WIKSTRÖM, Pernilla, BERGH, Anders

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