Search Results - "RUDDLE, F. H"

Phylogenetic reconstruction of vertebrate Hox cluster duplications by Bailey, W J, Kim, J, Wagner, G P, Ruddle, F H

“…In vertebrates and the cephalochordate, amphioxus, the closest vertebrate relative, Hox genes are linked in a single cluster. Accompanying the emergence of…”
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Primary structure of c‐kit: relationship with the CSF‐1/PDGF receptor kinase family–oncogenic activation of v‐kit involves deletion of extracellular domain and C terminus by Qiu, F. H., Ray, P., Brown, K., Barker, P. E., Jhanwar, S., Ruddle, F. H., Besmer, P.

“…The protein kinase domains of v‐kit, the oncogene of the acute transforming feline retrovirus HZ4‐FeSV (HZ4‐feline sarcoma virus), CSF‐1R (macrophage colony…”
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The Evolution of the Vertebrate Dlx Gene Family by Stock, David W., Ellies, Debra L., Zhao, Zhiyong, Ekker, Marc, Ruddle, Frank H., Weiss, Kenneth M.

“…The vertebrate Dlx gene family consists of homeobox-containing transcription factors distributed in pairs on the same chromosomes as the Hox genes. To…”
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Expansion of the Hox Gene Family and the Evolution of Chordates by Pendleton, John W., Nagai, Brian K., Murtha, Michael T., Ruddle, Frank H.

“…Homeobox genes encode DNA-binding transcription regulators that participate in the formation of embryonic pattern or contribute to cell-type specificity during…”
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Two Steps in the Evolution of Antennapedia-Class Vertebrate Homeobox Genes by Kappen, Claudia, Schughart, Klaus, Ruddle, Frank H.

“…Antennapedia-class vertebrate homeobox genes have been classified with regard to their chromosomal locations and nucleotide sequence similarities within the…”
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Duplication of Large Genomic Regions during the Evolution of Vertebrate Homeobox Genes by Schughart, Klaus, Kappen, Claudia, Ruddle, Frank H.

“…The phylogenetic relationships of 21 murine Antp-class (Drosophila mutation Antennapedia-type class) homeobox genes have been analyzed, and several groups of…”
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Use of a Protein-Blotting Procedure and a Specific DNA Probe to Identify Nuclear Proteins That Recognize the Promoter Region of the Transferrin Receptor Gene by Miskimins, W. Keith, Roberts, Michael P., McClelland, Alan, Ruddle, Frank H.

“…We describe a procedure for detecting high-affinity, sequence-specific DNA-binding proteins from crude nuclear extracts. The technique utilizes electrophoretic…”
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Early evolutionary origin of major homeodomain sequence classes by Kappen, C, Schughart, K, Ruddle, F H

“…We have analyzed the relationships of 337 homeodomain and related sequences using a distance matrix approach. Based on our results, homeodomain sequences can…”
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Detection of Homeobox Genes in Development and Evolution by Murtha, Michael T., Leckman, James F., Ruddle, Frank H.

“…The homeobox genes encode a family of DNA-binding regulatory proteins whose function and genomic organization make them an important model system for the study…”
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Combinations of Closely Situated Cis-Acting Elements Determine Tissue-Specific Patterns and Anterior Extent of Early Hoxc8 Expression by Shashikant, Cooduvalli S., Ruddle, Frank H.

“…We have used a transgene mutation approach to study how expression domains of Hoxc8 are established during mouse embryogenesis. A cis-regulatory region located…”
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Evidence for Positive and Negative Regulation of the Hox-3.1 Gene by Bieberich, Charles J., Utset, Manuel F., Awgulewitsch, Alexander, Ruddle, Frank H.

“…The region-specific patterns of expression of mouse homeobox genes are considered important for establishing the embryonic body plan. A 5-kilobase (kb) DNA…”
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Genetic Transformation of Mouse Embryos by Microinjection of Purified DNA by Gordon, Jon W., Scangos, George A., Plotkin, Diane J., Barbosa, James A., Ruddle, Frank H.

“…A recombinant plasmid composed of segments of herpes simplex virus and simian virus 40 viral DNA inserted into the bacterial plasmid pBR322 was microinjected…”
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Selective expression of mRNA coding for the truncated form of erythropoietin receptor in hematopoietic cells and its decrease in patients with polycythemia vera by CHIBA, S, TAKAHASHI, T, TAKESHITA, K, MINOWADA, J, YAZAKI, Y, RUDDLE, F. H, HIRAI, H

“…The mRNA encoding full-length erythropoietin (EPO) receptor (EPOR-F) comprises exons I through VIII. Another membrane-bound EPOR (EPOR-T) isoform has a…”
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Vertebrate Genome Evolution—The Decade Ahead by Ruddle, Frank H.

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Multiplex Gene Regulation: A Two-Tiered Approach to Transgene Regulation in Transgenic Mice by Byrne, G. W., Ruddle, F. H.

“…Transgenic mice have been used to study gene function and regulation by introducing inducible or tissue-specific transgenes. This approach is generally limited…”
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A Homeobox Gene of the Antennapedia Class is Required for Human Adult Erythropoiesis by Takeshita, Kenichi, Bollekens, Jacques A., Hijiya, Nobuko, Ratajczak, Mariusz, Ruddle, Frank H., Gewirtz, Alan M.

“…In this report we investigate the role of homeobox genes of the Antennapedia class in adult erythropoiesis, the process by which erythrocytes are formed in the…”
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A new era in mammalian gene mapping: somatic cell genetics and recombinant DNA methodologies by Ruddle, F. H

“…Mammalian gene mapping techniques are now sufficiently advanced to contribute significantly to prenatal diagnosis and to human molecular genetics. Restriction…”
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A Long-Range Regulatory Element of Hoxc8 Identified by Using the pClasper Vector by Bradshaw, M. Suzanne, Shashikant, Cooduvalli S., Belting, Heinz-Georg, Bollekens, Jacques A., Ruddle, Frank H.

“…Hox genes are located in highly conserved clusters. The significance of this organization is unclear, but one possibility is that regulatory regions for…”
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KRAS2 as a genetic marker for lung tumor susceptibility in inbred mice by Ryan, J, Barker, P E, Nesbitt, M N, Ruddle, F H

“…An Eco-RI restriction fragment length polymorphism occurring in a DNA fragment containing the first exon of the murine KRAS2 gene was shown to correlate with…”
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Transcriptional regulation by iron of the gene for the transferrin receptor by KRISHNAMURTHY RAO, HARFORD, J. B, ROUAULT, T, MCCLELLAND, A, RUDDLE, F. H, KLAUSNER, R. D

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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