Search Results - "RUCKER, Natalie"

Targeting Survivin Enhances Chemosensitivity in Retinoblastoma Cells and Orthotopic Tumors by Ferrario, Angela, Luna, Marian, Rucker, Natalie, Wong, Sam, Lederman, Ariel, Kim, Jonathan, Gomer, Charles

“…Treatments for retinoblastoma (Rb) vary depending on the size and location of the intraocular lesions and include chemotherapy and radiation therapy. We…”
Get full text

Survivin, a member of the inhibitor of apoptosis family, is induced by photodynamic therapy and is a target for improving treatment response by FERRARIO, Angela, RUCKER, Natalie, WONG, Sam, LUNA, Marian, GOMER, Charles J

“…We observed that photodynamic therapy (PDT) induces the expression and phosphorylation of the inhibitor of apoptosis (IAP) protein survivin in murine and human…”
Get full text

Photodynamic therapy: Combined modality approaches targeting the tumor microenvironment by Gomer, Charles J., Ferrario, Angela, Luna, Marian, Rucker, Natalie, Wong, Sam

“…Background and Objectives Photodynamic therapy causes direct cytotoxicity to malignant cells within a tumor. Photodynamic therapy (PDT) can also have both…”
Get full text

Celecoxib and NS-398 enhance photodynamic therapy by increasing in vitro apoptosis and decreasing in vivo inflammatory and angiogenic factors by FERRARIO, Angela, FISHER, Anita M, RUCKER, Natalie, GOMER, Charles J

“…Photodynamic therapy (PDT) elicits both apoptotic and necrotic responses within treated tumors and produces microvascular injury leading to inflammation and…”
Get full text

Pro-apoptotic and anti-inflammatory properties of the green tea constituent epigallocatechin gallate increase photodynamic therapy responsiveness by Ferrario, Angela, Luna, Marian, Rucker, Natalie, Wong, Sam, Gomer, Charles J.

“…Background A polyphenol constituent of green tea, epigallocatechin gallate (EGCG), has anti‐carcinogenic properties. A growing number of studies document…”
Get full text

Properties and Applications of Photodynamic Therapy by Gomer, Charles J., Rucker, Natalie, Ferrario, Angela, Wong, Sam

“…Photodynamic therapy (PDT) is the treatment of malignant lesions with visible light following the systemic administration of a tumor-localizing…”
Get full text

Increased transcription and translation of heme oxygenase in Chinese hamster fibroblasts following photodynamic stress or Photofrin II incubation by Gomer, C J, Luna, M, Ferrario, A, Rucker, N

“…Porphyrin mediated photosensitization can enhance the transcription and translation of several oxidative stress genes. In this study, we report on the enhanced…”
Get more information

Molecular, cellular, and tissue responses following photodynamic therapy by Gomer, C J, Ferrario, A, Hayashi, N, Rucker, N, Szirth, B C, Murphree, A L

“…Photodynamic therapy (PDT) is being utilized in the treatment of a wide variety of malignant tumors. Results using PDT have been encouraging, and controlled…”
Get more information

Abstract 2512: Combining radiation or carboplatin with targeted inhibition of survivin increases treatment induced apoptosis in retinoblastoma cells by Luna, Marian, Ferrario, Angela, Rucker, Natalie, Wong, Sam, Gomer, Charles J.

“…The overarching goal of this project is to evaluate clinically relevant protocols to improve treatment responses for retinoblastoma (Rb). Procedures to treat…”
Get full text

Antiangiogenic treatment enhances photodynamic therapy responsiveness in a mouse mammary carcinoma by FERRARIO, A, VON TIEHL, K. F, RUCKER, N, SCHWARZ, M. A, GILL, P. S, GOMER, C. J

“…Photodynamic therapy (PDT) is a promising cancer treatment that induces localized tumor destruction via the photochemical generation of cytotoxic singlet…”
Get full text

The matrix metalloproteinase inhibitor Prinomastat enhances photodynamic therapy responsiveness in a mouse tumor model by FERRARIO, Angela, CHANTRAIN, Christophe F, VON TIEHL, Karl, BUCKLEY, Sue, RUCKER, Natalie, SHALINSKY, David R, SHIMADA, Hiroyuki, DECLERCK, Yves A, GOMER, Charles J

“…Photodynamic therapy (PDT) clinical results are promising; however, tumor recurrences can occur and, therefore, methods for improving treatment efficacy are…”
Get full text

Pro-apoptotic and anti-inflammatory properties of the green tea constituent epigallocatechin gallate increase photodynamic therapy responsiveness: EGCG ENHANCES PDT RESPONSIVENESS by Ferrario, Angela, Luna, Marian, Rucker, Natalie, Wong, Sam, Gomer, Charles J.

Get full text

Multiple Components of Photodynamic Therapy Can Phosphorylate Akt by Bozkulak, Ozguncem, Wong, Sam, Luna, Marian, Ferrario, Angela, Rucker, Natalie, Gulsoy, Murat, Gomer, Charles J.

“…A growing number of clinically relevant molecular and cellular responses are observed following photodynamic therapy (PDT). PDT‐mediated oxidative stress and…”
Get full text

Photodynamic therapy-mediated oxidative stress can induce expression of heat shock proteins by GOMER, C. J, RYTER, S. W, FERRARIO, A, RUCKER, N, WONG, S, FISHER, A. M. R

“…Photodynamic therapy (PDT) is an experimental cancer therapy inducing tumor tissue damage via photosensitizer-mediated oxidative cytotoxicity. A previous…”
Get full text

Dichtigkeitsuntersuchung Von Sechs Unterschiedlichen Wurzelkanalfüllmaterialien - Eine Langzeitstudie by Rucker, Natalie

“…1.1 Hintergrund und Ziele Die moderne Endodontie stellt hohe Ansprüche an die werkstoffkundlichen Eigenschaften von Wurzelkanalfüllmaterialien. Eine ihrer…”
Get full text

Photodynamic therapy sensitivity is not altered in human tumor cells after abrogation of p53 function by FISHER, A. M. R, FERRARIO, A, RUCKER, N, SHA ZHANG, GOMER, C. J

“…Photodynamic therapy (PDT) is an effective local cancer treatment that induces cytotoxicity through the intracellular generation of reactive oxygen species…”
Get full text

Enhanced photodynamic therapy efficacy with inducible suicide gene therapy controlled by the grp promoter by LUNA, Marian C, XINKE CHEN, WONG, Sam, TSUI, Janet, RUCKER, Natalie, LEE, Amy S, GOMER, Charles J

“…Photodynamic therapy (PDT) is a promising cancer treatment involving the administration of a tumor-localizing photosensitizer followed by the photochemical…”
Get full text

Differential photosensitivity in wild-type and mutant p53 human colon carcinoma cell lines by Fisher, Anita M.R., Rucker, Natalie, Wong, Sam, Gomer, Charles J.

“…Tumor sensitivity to cancer therapies may be modulated by the p53 status of the malignant cells. Generally, tumors retaining wild-type p53 are more sensitive…”
Get full text

Glucose regulated protein induction and cellular resistance to oxidative stress mediated by porphyrin photosensitization by GOMER, C. J, FERRARIO, A, RUCKER, N, WONG, S, LEE, A. S

“…Photodynamic therapy (PDT) utilizes a tumor localizing porphyrin photosensitizer in the clinical treatment of cancer. At a mechanistic level, porphyrin…”
Get full text

Decreased expression and function of α-2 macroglobulin receptor/low density lipoprotein receptor-related protein in photodynamic therapy-resistant mouse tumor cells by LUNA, M. C, FERRARIO, A, RUCKER, N, GOMER, C. J

“…Parental and photodynamic therapy (PDT)-resistant mouse, radiation-induced fibrosarcoma cell lines were evaluated using mRNA differential display in an attempt…”
Get full text