Search Results - "RUBERTI, Mary F"

Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen by KOVTUN, Yelena V, AUDETTE, Charlene A, YUMEI YE, HONGSHENG XIE, RUBERTI, Mary F, PHINNEY, Sara J, LEECE, Barbara A, CHITTENDEN, Thomas, BLÄTTLER, Walter A, GOLDMACHER, Victor S

“…Conjugates of the anti-CanAg humanized monoclonal antibody huC242 with the microtubule-formation inhibitor DM1 (a maytansinoid), or with the DNA alkylator DC1…”
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Phase I Study of BB-10901 (huN901-DM1) in Patients with Relapsed and Relapsed/Refractory CD56-Positive Multiple Myeloma by Chanan-Khan, Asher Alban, Jagannath, Sundar, Schlossman, Robert L., Fram, Robert J., Falzone, Richard M., Ruberti, Mary F., Welch, Samantha K., DePaolo, Dawn, Anderson, Kenneth C., Munshi, Nikhil C.

“…Background: BB-10901 is a humanized monoclonal antibody that binds with high affinity to CD56 and is covalently linked to a novel cytotoxic maytansinoid DM1…”
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