Search Results - "RUBENS, Robert"

Precompetitive Consensus Building to Facilitate the Use of Digital Health Technologies to Support Parkinson Disease Drug Development through Regulatory Science by Stephenson, Diane, Alexander, Robert, Aggarwal, Varun, Badawy, Reham, Bain, Lisa, Bhatnagar, Roopal, Bloem, Bastiaan R., Boroojerdi, Babak, Burton, Jackson, Cedarbaum, Jesse M., Cosman, Josh, Dexter, David T., Dockendorf, Marissa, Dorsey, E. Ray, Dowling, Ariel V., Evers, Luc J. W., Fisher, Katherine, Frasier, Mark, Garcia-Gancedo, Luis, Goldsack, Jennifer C., Hill, Derek, Hitchcock, Janice, Hu, Michele T., Lawton, Michael P., Lee, Susan J., Lindemann, Michael, Marek, Ken, Mehrotra, Nitin, Meinders, Marjan J., Minchik, Michael, Oliva, Lauren, Romero, Klaus, Roussos, George, Rubens, Robert, Sadar, Sakshi, Scheeren, Joseph, Sengoku, Eiichi, Simuni, Tanya, Stebbins, Glenn, Taylor, Kirsten I., Yang, Beatrice, Zach, Neta

“…Innovative tools are urgently needed to accelerate the evaluation and subsequent approval of novel treatments that may slow, halt, or reverse the relentless…”
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Dosing Patterns during Conversion to IPX066, Extended-Release Carbidopa-Levodopa (ER CD-LD), in Parkinson’s Disease with Motor Fluctuations by Khanna, Sarita, Rubens, Robert, Dhall, Rohit, Morgan, John C., Gupta, Suneel

“…Background. IPX066 is an extended-release (ER) oral formulation of carbidopa-levodopa (CD-LD). Following an initial peak at about one hour, plasma LD…”
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Next-day cognition, psychomotor function, and driving-related skills following nighttime administration of eszopiclone by Boyle, Julia, Trick, Leanne, Johnsen, Sigurd, Roach, James, Rubens, Robert

“…Objective To evaluate next‐day driving ability, as assessed by brake reaction time (BRT), and cognitive/psychomotor function following nighttime administration…”
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A polysomnographic placebo-controlled evaluation of the efficacy and safety of eszopiclone relative to placebo and zolpidem in the treatment of primary insomnia by Erman, Milton K, Zammit, Gary, Rubens, Robert, Schaefer, Kendyl, Wessel, Thomas, Amato, David, Caron, Judy, Walsh, James K

“…To evaluate the polysomnographic efficacy and the safety of a range of doses of eszopiclone relative to placebo in patients with primary insomnia. Zolpidem 10…”
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Clinical and pathological absence of cardiotoxicity after liposomal doxorubicin by Jones, Robin L, Berry, Gerald J, Rubens, Robert D, Miles, David W

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Bisphosphonate therapy for patients with breast carcinoma: Who to treat and when to stop by PLUNKETT, Timothy A, RUBENS, Robert D

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Influence of exogenous oestrogen or (anti-) androgen administration on soluble transferrin receptor in human plasma by T’Sjoen, Guy G, Beguin, Yves, Feyen, Els, Rubens, Robert, Kaufman, Jean-Marc, Gooren, Louis

“…The objective of this investigation was to study the effects of sex steroids on levels of haemoglobin (Hb) and haematocrit (Hct) and to analyse whether these…”
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Bisphosphonate therapy for patients with breast carcinoma by Plunkett, Timothy A., Rubens, Robert D.

“…Bisphosphonates have become well established in the treatment of patients with metastatic bone disease, although the optimal use of these agents has not been…”
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Safety and efficacy of TAK-925 in adults with obstructive sleep apnea who experience excessive daytime sleepiness despite adequate use of CPAP (4278) by Rubens, Robert, Olsson, Tina, Neuwirth, Rachel, Bialek, Sandy, Bogan, Richard, Maynard, James, Schwartz, Howard, Alexander, Robert

“…Abstract only…”
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Pharmacodynamics, Efficacy, and Safety of IPX203 in Parkinson Disease Patients With Motor Fluctuations by Modi, Nishit B, Mittur, Aravind, Dinh, Phillip, Rubens, Robert, Gupta, Suneel

“…IPX203 is an investigational oral extended-release capsule formulation of carbidopa and levodopa. The pharmacodynamics and efficacy of IPX203 were compared…”
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Dosing and efficacy of extended-release carbidopa-levodopa in advanced Parkinson’s disease patients with or without concomitant medication use (P1.027) by Gupta, Suneel, Khanna, Sarita, Kell, Sherron, Rubens, Robert

“…Abstract only…”
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Improvements in activities of daily living and quality of life measures in Hoehn & Yahr subgroups of advanced Parkinson’s disease patients following treatment with IPX066, extended-release carbidopa-levodopa (P4.008) by Dhall, Rohit, Gil, Ramon, Lindemulder, Elizabeth, Rubens, Robert, Gupta, Suneel

“…Abstract only…”
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Eszopiclone Co-Administered With Fluoxetine in Patients With Insomnia Coexisting With Major Depressive Disorder by Fava, Maurizio, McCall, W. Vaughn, Krystal, Andrew, Wessel, Thomas, Rubens, Robert, Caron, Judy, Amato, David, Roth, Thomas

“…Insomnia and major depressive disorder (MDD) can coexist. This study evaluated the effect of adding eszopiclone to fluoxetine. Patients who met DSM-IV criteria…”
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Efficacy of IPX066, Extended-Release Carbidopa-Levodopa: Subgroup Analysis in Advanced Parkinson’s Disease Patients with Troublesome Dyskinesia (P2.340) by Dhall, Rohit, Struck, Lynn, Rubens, Robert, Khanna, Sarita, Gupta, Suneel

“…Abstract only…”
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Dosing Patterns During Conversion to IPX066, Extended-Release Carbidopa-Levodopa, from Other Carbidopa-Levodopa Formulations in Advanced Parkinson’s Disease Patients (P2.338) by Morgan, John, Stacy, Mark, Rubens, Robert, Khanna, Sarita, Gupta, Suneel

“…Abstract only…”
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Comparison of IPX066 with carbidopa–levodopa plus entacapone in advanced PD patients by Stocchi, Fabrizio, Hsu, Ann, Khanna, Sarita, Ellenbogen, Aaron, Mahler, Andreas, Liang, Grace, Dillmann, Ulrich, Rubens, Robert, Kell, Sherron, Gupta, Suneel

“…Abstract Background IPX066, an investigational extended-release carbidopa–levodopa (CD-LD) preparation, has demonstrated a rapid attainment and prolonged…”
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Opt‐Out Design for an Observational Toxicology Study Involving Intoxicated Patients at a Dance Music Event by Calle, Paul, Blanckaert, Peter, Lemoyne, Sabine, Rubens, Robert

“…At electronic dance music events in Belgium in 2013 to 2015, seemingly intoxicated patients were included without their informed consent in an observational…”
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Nightly treatment of primary insomnia with eszopiclone for six months : Effect on sleep, quality of life, and work limitations by WALSH, James K, KRYSTAL, Andrew D, AMATO, David A, RUBENS, Robert, CARON, Judy, WESSEL, Thomas C, SCHAEFER, Kendyl, ROACH, James, WALLENSTEIN, Gene, ROTH, Thomas

“…To evaluate 6 months' eszopiclone treatment upon patient-reported sleep, fatigue and sleepiness, insomnia severity, quality of life, and work limitations…”
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Single-Dose Pharmacokinetics and Pharmacodynamics of IPX203 in Patients With Advanced Parkinson Disease: A Comparison With Immediate-Release Carbidopa-Levodopa and With Extended-Release Carbidopa-Levodopa Capsules by Modi, Nishit B, Mittur, Aravind, Rubens, Robert, Khanna, Sarita, Gupta, Suneel

“…IPX203 is an investigational oral extended-release capsule formulation of carbidopa-levodopa (CD-LD). The aim of this study was to characterize the single-dose…”
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Eszopiclone in patients with insomnia during perimenopause and early postmenopause : A randomized controlled trial by SOARES, Claudio N, JOFFE, Hadine, RUBENS, Robert, CARON, Judy, ROTH, Thomas, COHEN, Lee

“…To evaluate eszopiclone 3 mg for treatment of insomnia in perimenopausal and early postmenopausal women, as well as the impact of insomnia treatment on mood,…”
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