Search Results - "RSC pharmaceutics"

Programmable protein delivery from microgel/hydrogel composites (MHCs) via discrete combinations of multi-state protein-loaded unit ingredients by Chen, Longfei, Khan, Saif A.

“…Therapeutic proteins have drawn increasing attention in the development of advanced drugs and biomedical devices, yet there are outstanding challenges for the…”
Get full text

Biopharmaceutical advancement of efonidipine hydrochloride ethanolate through amorphous solid dispersion of a Parteck SLC mesoporous silica polymer by Bharati, Swati, Gaikwad, Vinod, Chellampillai, Bothiraja

“…Amorphous solid dispersion is the most efficient method for improving the solubility and release of poorly water-soluble crystalline drug molecules…”
Get full text

Approaches to enhance the antimicrobial activity of carbapenems within bacterial biofilms by Lamb, Matthew A., Wiedbrauk, Sandra, Fairfull-Smith, Kathryn E.

“…Carbapenems are crucial antibiotics in the battle against bacterial infections, targeting both Gram-positive and Gram-negative bacteria with exceptional…”
Get full text

Comparison of emulsion and spray methods for fabrication of rapamycin-loaded acetalated dextran microparticles by Ehrenzeller, Stephen A., Lukesh, Nicole Rose, Stiepel, Rebeca T., Middleton, Denzel D., Nuzzolo, Steven M., Tate, Aliyah J., Batty, Cole J., Bachelder, Eric M., Ainslie, Kristy M.

“…Rapamycin (rapa), an immunosuppressive medication, has demonstrated considerable effectiveness in reducing organ transplant rejection and treating select…”
Get full text

Supramolecular hydrogels enable co-delivery of chemotherapeutics with synergistic efficacy against patient-derived glioblastoma cells and spheroids by Cavanagh, Robert J., Baquain, Saif, Alexander, Cameron, Scherman, Oren A., Rahman, Ruman

“…Drug combinations have been shown to be highly effective in many cancer therapies but the ratios of the individual drugs must be adjusted carefully and…”
Get full text

The etiology, pathogenesis, treatment, and development of transdermal drug delivery systems for rheumatoid arthritis by Baig, Mirza Muhammad Faran Ashraf, Kwan, Chi Hin, Wu, Hongkai, Chair, Sek Ying

“…Rheumatoid arthritis (RA) is a long-term autoimmune disease that causes irreversible deformity of joints and disability of body parts. The symptoms include…”
Get full text

Tailoring lipid nanoparticle dimensions through manufacturing processes by McMillan, Caitlin, Druschitz, Amy, Rumbelow, Stephen, Borah, Ankita, Binici, Burcu, Rattray, Zahra, Perrie, Yvonne

“…Lipid nanoparticles (LNPs), most commonly recognised for their role in COVID-19 mRNA vaccines, are important delivery vehicles for nucleic acid (mRNA, siRNA)…”
Get full text

Dual-purpose resveratrol-quantum dots loaded albumin nanoparticles by Yadav, Deepankar, Chaudhary, Priyanka, Singh, Priya, Gupta, Monu, Saraf, Shubhini A.

“…Incorporating therapeutic and imaging capabilities into core–shell structured nanoparticles (NPs) has shown promising results in cancer treatment. This study…”
Get full text

Functionalized SBA-15: engineering, detailed study on release and kinetics of alendronate as well as its anti-tumour properties towards osteosarcoma by Patel, Anjali, Mehta, Shivangi

“…The present work deals with designing a biocompatible controlled drug delivery system (DDS) based on 12-tungstophosphoric acid (TPA)-functionalized SBA-15 for…”
Get full text

Cancer immunotherapy boosted by layered double hydroxide nanoparticles by Deng, Xiaochun, Li, Gaoming, Shen, Mingwu, Shi, Xiangyang

“…The development of innovative nanoplatforms for cancer immunotherapy has garnered considerable attention in biomedical research. Layered double hydroxide (LDH)…”
Get full text

Nose to brain targeting of the donepezil nanostructured lipid carrier in situ gel: formulation, in vitro , ex vivo , in vivo pharmacokinetic and pharmacodynamic characterization by Sonawane, Devika, Pokharkar, Varsha

“…Donepezil (DPZ) is a reversible, noncompetitive inhibitor of acetylcholinesterase commonly prescribed against Alzheimer's disease (AD). Its dose-dependent side…”
Get full text

Acid- and base-resistant antimicrobial hydrogels based on polyoxometalates and chitosan by McWilliams, Callum, Franco-Castillo, Isabel, Seral Ascaso, Andrés, García-Embid, Sonia, Malefioudaki, Mariella, Meier, Johann G., Martín-Rapún, Rafael, Mitchell, Scott G.

“…Invasive fungal infections kill more than 1.7 million and affect over a billion people each year; however, their devastating impact on human health is not…”
Get full text

A brief overview of quality by design approach for developing pharmaceutical liposomes as nano-sized parenteral drug delivery systems by Atre, Prachi, Rizvi, Syed A. A.

“…Liposomes are sophisticated drug delivery vehicles that have significantly broadened the range of therapeutic agents that can be selectively delivered along…”
Get full text

Pharmaceutical salts of azole anti-fungal drugs: physicochemical behaviour and activity studies by Qadri, Hafsa, Malik, Asif A., Ahangar, Aadil A., Mir, Manzoor Ahmad, Dar, Ajiaz A., Shah, Abdul Haseeb

“…Pharmaceutical cocrystal engineering is a potential and growing strategy for modulating the physicochemical and pharmacokinetic properties of drug molecules…”
Get full text

Target-selective cytosolic delivery of cargo proteins using the VHH-presented OLE-ZIP capsules by Takahashi, Kousuke, Inoue, Yasumichi, Hida, Shigeaki, Hosoda, Ryuki, Umezawa, Naoki, Akiba, Isamu, Umetsu, Mitsuo, Mizuno, Toshihisa

“…In the pursuit of a new generation of protein pharmaceuticals, the efficient delivery of these therapeutics into cells stands out as a crucial challenge. In…”
Get full text

Recent progress on nanosystems for nucleic acid delivery by Walia, Shanka, Mehta, Mohit J.

“…Nucleic acid (NA) based therapeutics have witnessed tremendous progress and breakthroughs in treating pathological conditions, including viral infections,…”
Get full text

Effect of leucine as an aerosolization enhancer on the bioactivity of spray dried viral-vectored vaccines for inhalation by Singh, Varsha, Dolovich, Myrna, Xing, Zhou, Cranston, Emily D., Thompson, Michael R.

“…Aerosolization enhancers, like l -leucine, can improve deep-lung deposition of inhalable dry powders although the implications of their use have not yet been…”
Get full text

Correction: Pharmaceutical salts of azole anti-fungal drugs: physicochemical behaviour and activity studies by Qadri, Hafsa, Malik, Asif A., Ahangar, Aadil A., Mir, Manzoor Ahmad, Dar, Aijaz A., Shah, Abdul Haseeb

“…Correction for ‘Pharmaceutical salts of azole anti-fungal drugs: physicochemical behaviour and activity studies’ by Hafsa Qadri et al. , RSC Pharm. , 2024,…”
Get full text

Effect of amorphous chrysin loading in hydrophobically modified Pluronic F68 nanomicelles on its anticancer activity, stability and oral bioavailability by Narayan, Harihar, Jangid, Ashok Kumar, Sharma, Jiten R., Kishore, Ankita, Mahor, Alok Kumar, Yadav, Umesh C. S., Kulhari, Hitesh, Singh, Prem Prakash

“…Designing a potential polymer-based drug delivery carrier is of great significance for enhancing the anticancer effectiveness and oral delivery of hydrophobic…”
Get full text

Multilamellar nanovectors composed of microbial glycolipid–polylysine complexes for drug encapsulation by Alonso-de-Castro, Silvia, Formoso, Sergio Oliveira, Seyrig, Chloé, Ozkaya, Korin, Dumont, Julien, Riancho, Luisa, Perez, Javier, Hélary, Christophe, Baccile, Niki

“…This study addresses the potential use of single-glucose microbial amphiphiles as pohospholipid-free drug carriers. Microbial amphiphiles, also known as…”
Get full text