Search Results - "RS, Mani"

The Molecular Architecture of the Mammalian DNA Repair Enzyme, Polynucleotide Kinase by Bernstein, Nina K., Williams, R. Scott, Rakovszky, Melissa L., Cui, Diana, Green, Ruth, Karimi-Busheri, Feridoun, Mani, Rajam S., Galicia, Sarah, Koch, C. Anne, Cass, Carol E., Durocher, Daniel, Weinfeld, Michael, Glover, J.N. Mark

“…Mammalian polynucleotide kinase (PNK) is a key component of both the base excision repair (BER) and nonhomologous end-joining (NHEJ) DNA repair pathways. PNK…”
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A rare case of Japanese encephalitis-induced anti-N-methyl-d-aspartate receptor encephalitis by Shaik, Reshma, Netravathi, M, Nitish, L, Mani, R, Shah, P, Damodar, T, Anita, M, Pal, P

“…In view of recurrent neuropsychiatric disturbances, she was re-evaluated and found to have positive JE titers and anti-NMDAR titers in both serum and…”
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Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines by MACKEY, J. R, MANI, R. S, SELNER, M, MOWLES, D, YOUNG, J. D, BELT, J. A, CRAWFORD, C. R, CASS, C. E

“…Gemcitabine (2',2'-difluorodeoxycytidine) is a novel pyrimidine nucleoside drug with clinical efficacy in several common epithelial cancers. We have proposed…”
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Rabies following mongoose bite by Mani, RS, Moorkoth, AP, Balasubramanian, P, Devi, KLS, Madhusudana, SN

“…Dear Editor, We report a case of human rabies following mongoose bite, highlighting the atypical clinical manifestations, diagnostic challenges, the role of…”
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Biophysical Characterization of Human XRCC1 and Its Binding to Damaged and Undamaged DNA by Mani, Rajam S, Karimi-Busheri, Feridoun, Fanta, Mesfin, Caldecott, Keith W, Cass, Carol E, Weinfeld, Michael

“…The human DNA repair protein, hXRCC1, which is required for DNA single-strand break repair and genetic stability was produced as a histidine-tagged polypeptide…”
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Functional production and reconstitution of the human equilibrative nucleoside transporter (hENT1) in Saccharomyces cerevisiae. Interaction of inhibitors of nucleoside transport with recombinant hENT1 and a glycosylation-defective derivative (hENT1/N48Q) by Vickers, M F, Mani, R S, Sundaram, M, Hogue, D L, Young, J D, Baldwin, S A, Cass, C E

“…We have produced recombinant human equilibrative nucleoside transporter (hENT1) in the yeast Saccharomyces cerevisiae and have compared the binding of…”
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Fluorescence Energy Transfer Studies of Human Deoxycytidine Kinase:  Role of Cysteine 185 in the Conformational Changes that Occur upon Substrate Binding by Mani, Rajam S, Usova, Elena V, Cass, Carol E, Eriksson, Staffan

“…Human deoxycytidine kinase (dCK) phosphorylates both pyrimidine and purine deoxynucleosides, including numerous nucleoside analogue prodrugs. Energy transfer…”
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Spectroscopic Studies of DNA and ATP Binding to Human Polynucleotide Kinase:  Evidence for a Ternary Complex by Mani, Rajam S, Karimi-Busheri, Feridoun, Fanta, Mesfin, Cass, Carol E, Weinfeld, Michael

“…Human polynucleotide kinase (hPNK), which possesses both 5‘-DNA kinase and 3‘-DNA phosphatase activities, is a DNA repair enzyme required for processing and…”
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A novel method for differentiation of Candida dubliniensis from other Candida species by Wabale, VR, Kagal, AS, Mani, RS, Bharadwaj, R

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Demonstration of Equilibrative Nucleoside Transporters (hENT1 and hENT2) in Nuclear Envelopes of Cultured Human Choriocarcinoma (BeWo) Cells by Functional Reconstitution in Proteoliposomes by Mani, Rajam S., Hammond, James R., Marjan, Jihan M.J., Graham, Kathryn A., Young, James D., Baldwin, Stephen A., Cass, Carol E.

“…The equilibrative nucleoside transporters (ENTs) are a newly recognized family of membrane proteins of which hENT1 is the nitrobenzylmercaptopurine…”
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A novel method for differentiation of Candida dubliniensis from other Candida species by Wabale, VR, Kagal, AS, Mani, RS, Bharadwaj, R

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Physical Properties of Human Polynucleotide Kinase:  Hydrodynamic and Spectroscopic Studies by Mani, Rajam S, Karimi-Busheri, Feridoun, Cass, Carol E, Weinfeld, Michael

“…Human polynucleotide kinase (hPNK) is a putative DNA repair enzyme in the base excision repair pathway required for processing and rejoining strand-break…”
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Compatibilizing effects of block copolymers in low-density polyethylene/polystyrene blends by Guo, H.F., Packirisamy, S., Mani, R.S., Aronson, C.L., Gvozdic, N.V., Meier, D.J.

“…The phase and mechanical properties of a low-density polyethylene/polystyrene 70/30 (LDPE/PS 70/30) blend has been determined after compatibilization with…”
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Fluorescence Studies of Substrate Binding to Human Recombinant Deoxycytidine Kinase by Mani, R. S., Usova, E. V., Eriksson, S., Cass, C. E.

“…Deoxycytidine kinase (dCK), is responsible for the phosphorylation of deoxynucleosides to the corresponding monophosphates using ATP or UTP as phosphate…”
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Hydrodynamic and Spectroscopic Studies of Substrate Binding to Human Recombinant Deoxycytidine Kinase by Mani, Rajam S., Usova, Elena V., Eriksson, Staffan, Cass, Carol E.

“…Deoxycytidine kinase (dCK), a cytosolic enzyme with broad substrate specificity, plays a key role in the activation of therapeutic nucleoside analogues by…”
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First Hop Security Considerations in IPV6 Implementation by Kumar, A, Mani, R.S

“…With the evolvement of IPv6 as next generation protocol in Internet, many security issues came into picture with its implementation. The security…”
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Calcium-dependent regulation of caldesmon by an 11-kDa smooth muscle calcium-binding protein, caltropin by Mani, Rajam S, McCubbin, William D, Kay, Cyril M

“…Caldesmon from chicken gizzard muscle has been examined for its ability to interact with caltropin using affinity chromatography and the fluorescent probe…”
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Effect of Caltropin on Caldesmon-Actin Interaction by Mani, R S, Kay, C M

“…The binding of chicken gizzard caldesmon to actin was studied both in the presence and the absence of caltropin using Airfuge centrifugation experiments,…”
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Influence of Caltropin on the Caldesmon Induced Polymerization of G-Actin by Mani, R.S., Kay, C.M.

“…The effect of caltropin (CaT) on the caldesmon (CaD)-G-actin interaction was monitored by viscosity measurements, bioassays measuring the release of inorganic…”
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Unique clinical and imaging findings in a first ever documented PCR positive rabies survival patient: A case report by M., Netravathi, V., Udani, RS, Mani, V., Gadad, M.A., Ashwini, M., Bhat, S, Mehta, A., Chowdhary, P.K., Pal, S.N., Madhusudana, P., Satishchandra

“…Highlights • Rabies survival cases are rare and around 12 cases have been reported till date. • Unique feature is the PCR positive rabies survival child 4½…”
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