Ganser-like Syndrome After Loss of Psychic Self-activation Syndrome: Psychogenic or Organic?

Very few data are available on the long-term changes in the cognitive abilities of patients with loss of psychic self-activation syndrome (LPSAS). Here, we present a 25-year follow-up study on a case of LPSAS resulting from bilateral pallidal lesions caused by carbon monoxide intoxication. Typical s...

Full description

Saved in:

Bibliographic Details
Published in:	Archives of clinical neuropsychology Vol. 29; no. 7; pp. 715 - 723
Main Authors:	KAPHAN, Elsa, BARBEAU, Emmanuel, ROYERE, Marie L, GUEDJ, Eric, PELLETIER, Jean, ALI CHERIF, André
Format:	Journal Article
Language:	English
Published:	Oxford Oxford University Press 01-11-2014
Subjects:	Adult Adult and adolescent clinical studies Akinetic Mutism - chemically induced Akinetic Mutism - diagnosis Akinetic Mutism - physiopathology Biological and medical sciences Brain - metabolism Brain - pathology Brain - physiopathology Carbon Monoxide Poisoning - complications Case Reports Factitious Disorders - chemically induced Factitious Disorders - diagnosis Factitious Disorders - etiology Female Follow-Up Studies Humans Medical sciences Miscellaneous Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Human Decision-making Nervous system diseases Basal ganglia Pallidal lesion Decision making Neuropsychological assessment Dissociative disorder Central nervous system Neuropsychological test Psychometrics Cognition Basal ganglion Encephalon Cerebral disorder Central nervous system disease Functional neuroimaging Poisoning Ganser syndrome Carbon monoxide CO intoxication Loss of psychic self-activation syndrome Functional imaging Emission tomography
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Very few data are available on the long-term changes in the cognitive abilities of patients with loss of psychic self-activation syndrome (LPSAS). Here, we present a 25-year follow-up study on a case of LPSAS resulting from bilateral pallidal lesions caused by carbon monoxide intoxication. Typical signs of LPSAS were observed, showing no changes in severity, but Ganser syndrome (GS) gradually developed and worsened during the follow-up period. GS is generally assumed to be a psychogenic syndrome, but an organic etiology has been suspected by the authors of several case reports. Here, atypical features of GS plead against the independence of GS and LPSAS. DaTSCAN and brain 18FDG-PET were performed. Since left hippocampal hypometabolism has been previously described in patients with functional amnesia, it is possible that long periods of mental inactivity may have psychological consequences, but the atypical features of GS also suggest that an organic mechanism may be involved.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Present address of E.B.: Centre de Recherche Cerveau and Cognition (CERCO), UMR 5549, Université Paul Sabatier Toulouse 3, CNRS, Faculté de médecine Rangueil, Toulouse, France.
ISSN:	0887-6177 1873-5843
DOI:	10.1093/arclin/acu046