Search Results - "ROWE, Christopher"
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Tau imaging: early progress and future directions
Published in Lancet neurology (2015)“…Summary Use of selective in-vivo tau imaging will enable improved understanding of tau aggregation in the brain, facilitating research into causes, diagnosis,…”
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Falling into line?: The hostile environment and the legend of the ‘Judges’ Revolt
Published in Modern law review (01-01-2022)“…In 2012 the Government made a number of controversial changes to the 'Immigration Rules', which it claimed would ‘comprehensively reform the approach taken…”
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California's Public Safety Realignment Act and prisoner mortality
Published in PloS one (28-04-2023)“…In 2011, a historic Supreme Court decision mandated that the state of California substantially reduce its prison population to alleviate overcrowding, which…”
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Imaging tau and amyloid-[beta] proteinopathies in Alzheimer disease and other conditions
Published in Nature reviews. Neurology (01-04-2018)“…Most neurodegenerative disorders are associated with aggregated protein deposits. In the case of Alzheimer disease (AD), extracellular amyloid-[beta] (A[beta])…”
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Imaging tau and amyloid-β proteinopathies in Alzheimer disease and other conditions
Published in Nature reviews. Neurology (01-04-2018)“…Key Points The clinical phenotypes of patients with proteinopathies do not always enable identification of the underlying cause of the disorder, especially in…”
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Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study
Published in Lancet neurology (01-04-2013)“…Summary Background Similar to most chronic diseases, Alzheimer's disease (AD) develops slowly from a preclinical phase into a fully expressed clinical…”
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NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease
Published in Alzheimer's & dementia (01-04-2018)“…In 2011, the National Institute on Aging and Alzheimer's Association created separate diagnostic recommendations for the preclinical, mild cognitive…”
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Fibre-specific white matter reductions in Alzheimer's disease and mild cognitive impairment
Published in Brain (London, England : 1878) (01-03-2018)“…'Fixel'-based analysis enables identification of fibre tract-specific abnormalities. Mito et al. offer new insights into the reduction of fibre connectivity in…”
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Clinical and cognitive trajectories in cognitively healthy elderly individuals with suspected non-Alzheimer's disease pathophysiology (SNAP) or Alzheimer's disease pathology: a longitudinal study
Published in Lancet neurology (01-09-2016)“…Summary Background Brain amyloid β (Aβ) deposition and neurodegeneration have been documented in about 50–60% of cognitively healthy elderly individuals (aged…”
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Why a new edition of Aristotle’s Eudemian Ethics?
Published in Circe de clásicos y modernos (01-12-2021)“…Abstract The present article contains the conference delivered by Prof. C.J. Rowe at the III International Ancient Philosophy Workshop (Buenos Aires,…”
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Brain amyloid imaging
Published in Journal of Nuclear Medicine (01-11-2011)“…Imaging of brain β-amyloid plaques with (18)F-labeled tracers for PET will likely be available in clinical practice to assist the diagnosis of Alzheimer…”
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Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture
Published in Nature communications (23-09-2020)“…Genetic association studies have identified 44 common genome-wide significant risk loci for late-onset Alzheimer’s disease (LOAD). However, LOAD genetic…”
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Cerebral quantitative susceptibility mapping predicts amyloid-β-related cognitive decline
Published in Brain (London, England : 1878) (01-08-2017)“…See Derry and Kent (doi:10.1093/awx167) for a scientific commentary on this article.The large variance in cognitive deterioration in subjects who test positive…”
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Bioaccumulation and effects of metals and trace elements from aquatic disposal of coal combustion residues: recent advances and recommendations for further study
Published in The Science of the total environment (01-07-2014)“…Advances have been made recently in assessing accumulation and effects of coal combustion residues (CCR). I provide a brief review of recent advancements,…”
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“The Calamity of So Long Life”: Life Histories, Contaminants, and Potential Emerging Threats to Long-lived Vertebrates
Published in Bioscience (01-07-2008)“…Persistent contaminants are ubiquitous in the environment, often present at concentrations that may jeopardize reproductive fitness only after long periods of…”
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Clinical diagnosis of Alzheimer's disease: recommendations of the International Working Group
Published in Lancet neurology (01-06-2021)“…In 2018, the US National Institute on Aging and the Alzheimer's Association proposed a purely biological definition of Alzheimer's disease that relies on…”
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The Centiloid Project: Standardizing quantitative amyloid plaque estimation by PET
Published in Alzheimer's & dementia (01-01-2015)“…Abstract Although amyloid imaging with PiB-PET ([C-11]Pittsburgh Compound-B positron emission tomography), and now with F-18-labeled tracers, has produced…”
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Advances in Brain Amyloid Imaging
Published in Seminars in nuclear medicine (01-05-2021)“…Amyloid-β (Aβ) PET imaging has now been available for over 15 years. The ability to detect Aβ in vivo has greatly improved the clinical and research landscape…”
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Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline
Published in Nature medicine (01-11-2022)“…A major unanswered question in the dementia field is whether cognitively unimpaired individuals who harbor both Alzheimer’s disease neuropathological hallmarks…”
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