Search Results - "ROUSSEAU, F. R"

Structurally diverse MDM2–p53 antagonists act as modulators of MDR-1 function in neuroblastoma by Chen, L, Zhao, Y, Halliday, G C, Berry, P, Rousseau, R F, Middleton, S A, Nichols, G L, Del Bello, F, Piergentili, A, Newell, D R, Lunec, J, Tweddle, D A

“…Background: A frequent mechanism of acquired multidrug resistance in human cancers is overexpression of ATP-binding cassette transporters such as the…”
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Autologous antileukemic immune response induced by chronic lymphocytic leukemia B cells expressing the CD40 ligand and interleukin 2 transgenes by Takahashi, S, Rousseau, R F, Yotnda, P, Mei, Z, Dotti, G, Rill, D, Hurwitz, R, Marini, F, Andreeff, M, Brenner, M K

“…Although the B cells of chronic lymphocytic leukemia (B-CLL cells) express both tumor-specific peptides and major histocompatibility complex (MHC) class I…”
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Community-based environmental management in Atlantic Canada: the impacts and spheres of influence of the Atlantic Coastal Action Program by McNeil, T Colleen, Rousseau, F R, Hildebrand, L P

“…The Atlantic Coastal Action Program (ACAP) is a unique, community-based program initiated by Environment Canada in 1991 to help Atlantic Canadians restore and…”
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Cancer vaccines: dream, reality, or nightmare? by BIAGI, E, ROUSSEAU, R. F, YVON, E, VIGOUREUX, S, DOTTI, G, BRENNER, M. K

“…Over the past 30 years, a multidisciplinary approach combining surgery, chemotherapy, and radiation has led to a dramatic improvement in survival for patients…”
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Local and systemic effects of an allogeneic tumor cell vaccine combining transgenic human lymphotactin with interleukin-2 in patients with advanced or refractory neuroblastoma by Rousseau, Raphaël F., Haight, Ann E., Hirschmann-Jax, Charlotte, Yvon, Eric S., Rill, Donna R., Mei, Zhuyong, Smith, Susan C., Inman, Shannon, Cooper, Kristine, Alcoser, Pat, Grilley, Bambi, Gee, Adrian, Popek, Edwina, Davidoff, Andrew, Bowman, Laura C., Brenner, Malcolm K., Strother, Douglas

“…In murine models, transgenic chemokine–cytokine tumor vaccines overcome many of the limitations of single-agent immunotherapy by producing the sequence of…”
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Bystander transfer of functional human CD40 ligand from gene-modified fibroblasts to B-chronic lymphocytic leukemia cells by Biagi, Ettore, Yvon, Eric, Dotti, Gianpietro, Amrolia, Persis J, Takahashi, Satoshi, Popat, Uday, Marini, Frank, Andreeff, Michael, Brenner, Malcolm K, Rousseau, Raphaël F

“…CD40 ligand (CD40L) is a good candidate molecule for the immunotherapy of B cell malignancies including B-chronic lymphocytic leukemia (B-CLL), because it may…”
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Cancer vaccines by Rousseau, R F, Hirschmann-Jax, C, Takahashi, S, Brenner, M K

“…Attempts to generate an anticancer immune response in vivo in patients with cancer have taken several forms. Although to date there have been relatively few…”
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Gene therapy for paediatric leukaemia by Rousseau, R F, Bollard, C M, Heslop, H E

“…Improvements in the chemotherapeutic and transplant regimens have had a significant impact in improving survival rates for paediatric leukaemia. However, there…”
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Community-based environmental management in Atlantic Canada : The impacts and spheres of influence of the atlantic coastal action program: Canada's ecosystem initiatives by MCNEIL, T. Colleen, ROUSSEAU, F. R, HILDEBRAND, L. P

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Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells by Yvon, Eric S., Vigouroux, Stephane, Rousseau, Raphael F., Biagi, Ettore, Amrolia, Persis, Dotti, Gianpietro, Wagner, Hans-Joachim, Brenner, Malcolm K.

“…Graft-versus-host disease (GVHD) represents one of the major complications of allogeneic hematopoietic stem cell transplantation. Techniques to prevent GVHD…”
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Immunotherapy of high-risk acute leukemia with a recipient (autologous) vaccine expressing transgenic human CD40L and IL-2 after chemotherapy and allogeneic stem cell transplantation by Rousseau, Raphaël F., Biagi, Ettore, Dutour, Aurélie, Yvon, Eric S., Brown, Michael P., Lin, Tiffany, Mei, Zhuyong, Grilley, Bambi, Popek, Edwina, Heslop, Helen E., Gee, Adrian P., Krance, Robert A., Popat, Uday, Carrum, George, Margolin, Judith F., Brenner, Malcolm K.

“…CD40L generates immune responses in leukemia-bearing mice, an effect that is potentiated by IL-2. We studied the feasibility, safety, and immunologic efficacy…”
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Transgenic expression of CD40L and interleukin-2 induces an autologous antitumor immune response in patients with non-Hodgkin's lymphoma by Takahashi, S, Yotnda, P, Rousseau, R F, Mei, Z, Smith, S, Rill, D, Younes, A, Brenner, M K

“…The malignant B cells of non-Hodgkin's lymphoma (B-NHL cells) express peptides derived from tumor-specific antigens such as immunoglobulin idiotypes, and also…”
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Vaccine therapies for pediatric malignancies by Rousseau, Raphaël F, Brenner, Malcolm K

“…Cancer vaccines are examples of active immunotherapy. In pediatric malignancy such active strategies may be particularly problematic because of immune…”
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Occult orbital neuroblastoma detected after administration of an antitumor vaccine by WILSON, Matthew W, MOSHFEGHI, Darius M, HAIK, Barrett G, HAIGHT, Ann E, HILL, D. Ashley, DAVIDOFF, Andrew M, ROUSSEAU, Raphael F, BOWMAN, Laura C

“…A 6-year-old girl with neuroblastoma developed swelling and erythema of her right upper eyelid following administration of an interleukin-2 and lymphotactin…”
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