Search Results - "ROTTNER, K"

A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo by Bestas, Burcu, Wimberger, Sandra, Degtev, Dmitrii, Madsen, Alexandra, Rottner, Antje K., Karlsson, Fredrik, Naumenko, Sergey, Callahan, Megan, Touza, Julia Liz, Francescatto, Margherita, Möller, Carl Ivar, Badertscher, Lukas, Li, Songyuan, Cerboni, Silvia, Selfjord, Niklas, Ericson, Elke, Gordon, Euan, Firth, Mike, Chylinski, Krzysztof, Taheri-Ghahfarokhi, Amir, Bohlooly-Y, Mohammad, Snowden, Mike, Pangalos, Menelaos, Nuttall, Barrett, Akcakaya, Pinar, Sienski, Grzegorz, Maresca, Marcello

“…Streptococcus pyogenes Cas9 (SpCas9) and derived enzymes are widely used as genome editors, but their promiscuous nuclease activity often induces undesired…”
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Cortactin deficiency causes increased RhoA/ROCK1-dependent actomyosin contractility, intestinal epithelial barrier dysfunction, and disproportionately severe DSS-induced colitis by Citalán-Madrid, A F, Vargas-Robles, H, García-Ponce, A, Shibayama, M, Betanzos, A, Nava, P, Salinas-Lara, C, Rottner, K, Mennigen, R, Schnoor, M

“…The intestinal epithelium constitutes a first line of defense of the innate immune system. Epithelial dysfunction is a hallmark of intestinal disorders such as…”
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Interplay between Rac and Rho in the control of substrate contact dynamics by Rottner, K., Hall, A., Small, J.V.

“…Background: Substrate anchorage and cell locomotion entail the initiation and development of different classes of contact sites, which are associated with the…”
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Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice by Mason, William J., Jafree, Daniyal J., Pomeranz, Gideon, Kolatsi-Joannou, Maria, Rottner, Antje K., Pacheco, Sabrina, Moulding, Dale A., Wolf, Anja, Kupatt, Christian, Peppiatt-Wildman, Claire, Papakrivopoulou, Eugenia, Riley, Paul R., Long, David A., Vasilopoulou, Elisavet

“…Plasma ultrafiltration in the kidney occurs across glomerular capillaries, which are surrounded by epithelial cells called podocytes. Podocytes have a unique…”
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Filopodia formation induced by active mDia2/Drf3 by BLOCK, J, STRADAL, T.E.B, HÄNISCH, J, GEFFERS, R, KÖSTLER, S.A, URBAN, E, SMALL, J.V, ROTTNER, K, FAIX, J

“…Filopodia are rod-shaped cell surface protrusions composed of a parallel bundle of actin filaments. Since filopodia frequently emanate from lamellipodia, it…”
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Influence of dental materials on dental MRI by Tymofiyeva, O, Vaegler, S, Rottner, K, Boldt, J, Hopfgartner, A J, Proff, P C, Richter, E J, Jakob, P M

“…To investigate the potential influence of standard dental materials on dental MRI (dMRI) by estimating the magnetic susceptibility with the help of the…”
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Three-dimensional localization of impacted teeth using magnetic resonance imaging by Tymofiyeva, O., Rottner, K., Jakob, P. M., Richter, E.-J., Proff, P.

“…Impacted teeth remain embedded in the jawbone beyond the normal eruption time with completed root growth. They can often get infected or damage neighboring…”
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Actin polymerization machinery: the finish line of signaling networks, the starting point of cellular movement by Disanza, A, Steffen, A, Hertzog, M, Frittoli, E, Rottner, K, Scita, G

“…Dynamic assembly of actin filaments generates the forces supporting cell motility. Several recent biochemical and genetic studies have revealed a plethora of…”
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Assembling an actin cytoskeleton for cell attachment and movement by Small, J.Victor, Rottner, K., Kaverina, I., Anderson, K.I.

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Dynamic MRI of the TMJ under physical load by Hopfgartner, A J, Tymofiyeva, O, Ehses, P, Rottner, K, Boldt, J, Richter, E-J, Jakob, P M

“…The objective of this study was to examine the kinematics of structures of the temporomandibular joint (TMJ) under physiological load while masticating. Radial…”
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Retraction notice to “In osteoclasts, dynamic microtubules and their associated protein EB1 control podosomes and bone resorption through cortactin” [Bone 48S2 (2011) S97] by Biosse-Duplan, M, Stephens, S, Lai, F.P.L, Oelkers, M, Rottner, K, Horne, W, Baron, R

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Zyxin is not colocalized with vasodilator-stimulated phosphoprotein (VASP) at lamellipodial tips and exhibits different dynamics to vinculin, paxillin, and VASP in focal adhesions by Rottner, K, Krause, M, Gimona, M, Small, J V, Wehland, J

“…Actin polymerization is accompanied by the formation of protein complexes that link extracellular signals to sites of actin assembly such as membrane ruffles…”
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Effect of bone conditioning on primary stability of FRIALIT-2® implants by Proff, P., Bayerlein, T., Rottner, K., Mai, R., Fanghänel, J., Gedrange, T.

“…Background: Primary stability is crucial to implants used for orthodontic anchorage. Bone condensing to enhance primary stability is controversial. Material…”
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RETRACTED: In osteoclasts, dynamic microtubules and their associated protein EB1 control podosomes and bone resorption through cortactin by Biosse-Duplan, M, Stephens, S, Lai, F.P.L, Oelkers, M, Rottner, K, Horne, W, Baron, R

“…This abstract has been retracted: please see Elsevier Policy on Article Withdrawal ( http://www.elsevier.com/locate/withdrawalpolicy ). This abstract has been…”
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A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk by Rottner, Antje K., Ye, Yingying, Navarro-Guerrero, Elena, Rajesh, Varsha, Pollner, Alina, Bevacqua, Romina J., Yang, Jing, Spigelman, Aliya F., Baronio, Roberta, Bautista, Austin, Thomsen, Soren K., Lyon, James, Nawaz, Sameena, Smith, Nancy, Wesolowska-Andersen, Agata, Fox, Jocelyn E. Manning, Sun, Han, Kim, Seung K., Ebner, Daniel, MacDonald, Patrick E., Gloyn, Anna L.

“…Identification of the genes and processes mediating genetic association signals for complex diseases represents a major challenge. As many of the genetic…”
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Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression by Mattis, Katia K., Krentz, Nicole A. J., Metzendorf, Christoph, Abaitua, Fernando, Spigelman, Aliya F., Sun, Han, Ikle, Jennifer M., Thaman, Swaraj, Rottner, Antje K., Bautista, Austin, Mazzaferro, Eugenia, Perez-Alcantara, Marta, Manning Fox, Jocelyn E., Torres, Jason M., Wesolowska-Andersen, Agata, Yu, Grace Z., Mahajan, Anubha, Larsson, Anders, MacDonald, Patrick E., Davies, Benjamin, den Hoed, Marcel, Gloyn, Anna L.

“…Aims/hypothesis Genome-wide studies have uncovered multiple independent signals at the RREB1 locus associated with altered type 2 diabetes risk and related…”
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Surface roughening in ion implanted 4H-silicon carbide by Capano, M. A., Ryu, S., Cooper, J. A., Melloch, M. R., Rottner, K., Karlsson, S., Nordell, N., Powell, A., Walker, D. E.

“…Silicon carbide (SiC) devices have the potential to yield new components with functional capabilities that far exceed components based on silicon devices…”
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SiC power devices for high voltage applications by Rottner, K, Frischholz, M, Myrtveit, T, Mou, D, Nordgren, K, Henry, A, Hallin, C, Gustafsson, U, Schöner, A

“…Silicon Carbide device technology is now evolving from a pure vision to a real alternative to silicon devices. The feasibility of SiC devices has been shown…”
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A novel post-and-core restoration system--results of three years of clinical application of the "Wuerzburg Post" by Rottner, K, Boldt, J, Proff, P, Spassov, A, Gredes, T, Mack, F, Richter, E J

“…The Wuerzburg Post is a new post-and-core restoration system designed to eliminate the weak parts of post-and-core restorations and the associated problems,…”
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The making of filopodia by Faix, Jan, Rottner, Klemens

“…Filopodia are rod-like cell surface projections filled with bundles of parallel actin filaments. They are found on a variety of cell types and have been…”
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