Search Results - "ROTTMAN, FRITZ"

An in vitro System for Accurate Methylation of Internal Adenosine Residues in Messenger RNA by Narayan, Prema, Rottman, Fritz M.

“…Some internal adenosine residues in messenger RNA are methylated posttranscriptionally in the nucleus. Most of the methylated adenosine residues in prolactin…”
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Mapping the SF2/ASF Binding Sites in the Bovine Growth Hormone Exonic Splicing Enhancer by Dirksen, W P, Li, X, Mayeda, A, Krainer, A R, Rottman, F M

“…Splicing of the last intron (intron D) of the bovine growth hormone pre-mRNA requires the presence of a downstream exonic splicing enhancer (ESE). This…”
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Multiple Splicing Signals Control Alternative Intron Retention of Bovine Growth Hormone Pre-mRNA (∗) by Dirksen, Wessel P., Sun, Qiang, Rottman, Fritz M.

“…A fraction of bovine growth hormone (bGH) pre-mRNA undergoes alternative splicing in which the last intron is retained and transported to the cytoplasm. Our…”
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Identification of Methylated Nucleosides in Messenger RNA from Novikoff Hepatoma Cells by Desrosiers, Ronald, Friderici, Karen, Rottman, Fritz

“…The poly(A) tract found in eukaryotic mRNA was used to study methylation in mRNA obtained from Novikoff hepatoma cells. Methyl labeling of RNA was achieved…”
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SR proteins ASF/SF2 and 9G8 interact to activate enhancer-dependent intron D splicing of bovine growth hormone pre-mRNA in vitro by LI, XINLAN, SHAMBAUGH, MARY EILEEN, ROTTMAN, FRITZ M., BOKAR, JOSEPH A.

“…The alternative splicing of the last intron (intron D) of bovine growth hormone (bGH) pre-mRNA requires a downstream exonic splicing enhancer (FP/ESE). The…”
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Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase by Bokar, J A, Shambaugh, M E, Polayes, D, Matera, A G, Rottman, F M

“…The methylation of internal adenosine residues in eukaryotic mRNA, forming N6-methyladenosine (m6A), is catalyzed by a complex multicomponent enzyme. Previous…”
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Sequences containing methylated nucleotides at the 5' termini of messenger RNAs: possible implications for processing by Rottman, F, Shatkin, A J, Perry, R P

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Characterization of Novikoff hepatoma mRNA methylation and heterogeneity in the methylated 5' terminus by Desrosiers, Ronald C, Friderici, Karen H, Rottman, Fritz M

“…KOH digestion of methyl-labeled poly(A)+ mRNA purified by (dT)-cellulose chromatography produced mononucleotide and multiple peaks of a large oligonucleotide…”
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General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer by Sun, Q, Mayeda, A, Hampson, R K, Krainer, A R, Rottman, F M

“…The general splicing factor SF2/ASF binds in a sequence-specific manner to a purine-rich exonic splicing enhancer (ESE) in the last exon of bovine growth…”
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Accurate and efficient N-6-adenosine methylation in spliceosomal U6 small Nucelar RNA by HeLa cell extract in vitro by Shimba, Shigeki, Bokar, Joseph A., Rottman, Fritz, Reddy, Ram

“…Human U6 small nuclear RNA (U6 snRNA), an abundant snRNA required for splicing of pre-mRNAs, contains several post-transcrlptional modifications Including a…”
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A purine-rich exon sequence enhances alternative splicing of bovine growth hormone pre-mRNA by Dirksen, W.P, Hampson, R.K, Sun, Q, Rottman, F.M

“…A previous study has demonstrated that deletion of a region within the last exon of bovine growth hormone (bGH) pre-mRNA results in almost complete retention…”
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Recombinant Schistosoma mansoni 3-hydroxymethylglutaryl-coenzyme-A reductase has different inhibitor kinetics compared to the mammalian host enzyme by El-Meanawy, Ashraf, Hammd, Hammad, Chen, Guo-Zhong, Rottman, Fritz, Bennett, James L

“…Previous publications have clearly demonstrated that hydroxymethylglutaryl coenzyme A [HMG-CoA] reductase activity of Schistosoma mansoni is vital for parasite…”
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A Spliced Leader is Present on a Subset of mRNAs from the Human Parasite Schistosoma mansoni by Rajkovic, Aleksandar, Davis, Richard E., Simonsen, J. Neil, Rottman, Fritz M.

“…We present evidence that a subset of mRNAs in the human parasitic trematode Schistosoma mansoni contain an identical 36-nucleotide spliced leader (SL) sequence…”
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The 3'-flanking sequence of the bovine growth hormone gene contains novel elements required for efficient and accurate polyadenylation by Goodwin, E.C. (Case Western Reserve University, Cleveland, OH), Rottman, F.M

“…In addition to the conserved AAUAAA hexanucleotide, GU- and U-rich sequences in the 3'-flanking region are thought to be critical for efficient…”
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Ribonuclease and Oligoribonucleotide Synthesis by Bernfield, Merton R., Rottman, Fritz M.

“…The nucleotides, 5'- O -phosphoryl uridine 2',3'-cyclic phosphate and 5'- O -methylphosphoryl uridine 2',3'-cyclic phosphate, and the dinucleotides obtained…”
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In vitro analysis of bovine growth hormone pre-mRNA alternative splicing. Involvement of exon sequences and trans-acting factor(s) by Sun, Q, Hampson, R K, Rottman, F M

“…Bovine growth hormone (bGH) pre-mRNA is alternatively spliced, resulting in retention of the last intron (intron D) in a fraction of the cytosolic bGH mRNA. To…”
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c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor by Nilsen, T W, Maroney, P A, Goodwin, R G, Rottman, F M, Crittenden, L B, Raines, M A, Kung, H J

“…ALV-induced erythroblastosis results from the specific interruption of the host oncogene, c-erbB, by the insertion of an intact provirus. Integrated proviruses…”
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Context effects on N 6 -adenosine methylation sites in prolactin mRNA by Narayan, Prema, Ludwiczak, Rachael L., Goodwin, Edward C., Rottman, Fritz M.

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The use of RNase H and poly(A) junction oligonucleotides in the analysis of in vitro polyadenylation reaction products by Goodwin, Edward C., Rottman, Fritz M.

“…We have developed a technique that represents a significant improvement over other methods of analysis of in vitro polyadenylation reaction products by…”
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Alternative Processing of Bovine Growth Hormone mRNA: Nonsplicing of the Final Intron Predicts a High Molecular Weight Variant of Bovine Growth Hormone by Hampson, Robert K., Rottman, Fritz M.

“…We have detected a variant species of bovine growth hormone mRNA in bovine pituitary tissue and in a stably transfected bovine growth hormone-producing cell…”
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