Search Results - "ROSSIER, JEAN"
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Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1−/y mice
Published in Nature neuroscience (01-12-2014)“…Fragile X Syndrome (FXS) patients and the mouse model of the disease are known to have increased neocortical network excitability and hypersensitivity to…”
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2
Regulation of perineuronal nets in the adult cortex by the activity of the cortical network
Published in The Journal of neuroscience (07-07-2021)“…Perineuronal net (PNN) accumulation around parvalbumin-expressing (PV) inhibitory interneurons marks the closure of critical periods of high plasticity,…”
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3
Single-cell transcriptomic evidence for dense intracortical neuropeptide networks
Published in eLife (11-11-2019)“…Seeking new insights into the homeostasis, modulation and plasticity of cortical synaptic networks, we have analyzed results from a single-cell RNA-seq study…”
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4
Lactate is an energy substrate for rodent cortical neurons and enhances their firing activity
Published in eLife (12-11-2021)“…Glucose is the mandatory fuel for the brain, yet the relative contribution of glucose and lactate for neuronal energy metabolism is unclear. We found that…”
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Classification of NPY-Expressing Neocortical Interneurons
Published in The Journal of neuroscience (18-03-2009)“…Neuropeptide Y (NPY) is an abundant neuropeptide of the neocortex involved in numerous physiological and pathological processes. Because of the large…”
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Serotonin 3A Receptor Subtype as an Early and Protracted Marker of Cortical Interneuron Subpopulations
Published in Cerebral cortex (New York, N.Y. 1991) (01-10-2010)“…To identify neocortical neurons expressing the type 3 serotonergic receptor, here we used transgenic mice expressing the enhanced green fluorescent protein…”
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7
Wiring and plumbing in the brain
Published in Frontiers in human neuroscience (24-02-2009)“…The general assumption, which is supported by PET findings showing comparable functional increases in blood flow and glucose uptake (Raichle and Mintun, 2006),…”
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Cortical GABA Interneurons in Neurovascular Coupling: Relays for Subcortical Vasoactive Pathways
Published in The Journal of neuroscience (13-10-2004)“…The role of interneurons in neurovascular coupling was investigated by patch-clamp recordings in acute rat cortical slices, followed by single-cell reverse…”
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Functional CB1 Receptors Are Broadly Expressed in Neocortical GABAergic and Glutamatergic Neurons
Published in Journal of neurophysiology (01-04-2007)“…1 Laboratoire de Neurobiologie et Diversité Cellulaire, Centre National de la Recherche Scientifique Unité Mixte de Recherche 7637, Ecole Supérieure de…”
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10
Impaired neurovascular coupling in the APPxPS1 mouse model of Alzheimer's disease
Published in Current Alzheimer research (01-12-2012)“…The tight coupling between neuronal activity and the local increase of blood flow termed neurovascular coupling is essential for normal brain function. This…”
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Constitutive Endocytic Cycle of the CB1 Cannabinoid Receptor
Published in The Journal of biological chemistry (20-08-2004)“…The CB1 cannabinoid receptor (CB1R) displays a significant level of ligand-independent ( i.e. constitutive) activity, either when heterologously expressed in…”
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Neuronal Pentraxin 2 Binds PNNs and Enhances PNN Formation
Published in Neural plasticity (2019)“…The perineuronal net (PNN) is a mesh-like proteoglycan structure on the neuronal surface which is involved in regulating plasticity. The PNN regulates…”
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13
Constitutive Activation Drives Compartment-Selective Endocytosis and Axonal Targeting of Type 1 Cannabinoid Receptors
Published in The Journal of neuroscience (22-03-2006)“…The type 1 cannabinoid receptor (CB1R) is one of the most abundant G-protein-coupled receptors (GPCRs) in the brain, predominantly localized to axons of…”
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14
Landscape of protein–protein interactions in Drosophila immune deficiency signaling during bacterial challenge
Published in Proceedings of the National Academy of Sciences - PNAS (25-06-2013)“…The Drosophila defense against pathogens largely relies on the activation of two signaling pathways: immune deficiency (IMD) and Toll. The IMD pathway is…”
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15
Glutamatergic Control of Microvascular Tone by Distinct GABA Neurons in the Cerebellum
Published in The Journal of neuroscience (28-06-2006)“…The tight coupling between increased neuronal activity and local cerebral blood flow, known as functional hyperemia, is essential for normal brain function…”
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16
Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development
Published in BMC genomics (30-03-2009)“…Down syndrome is a chromosomal disorder caused by the presence of three copies of chromosome 21. The mechanisms by which this aneuploidy produces the complex…”
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17
Characterization of Type I and Type II nNOS-Expressing Interneurons in the Barrel Cortex of Mouse
Published in Frontiers in neural circuits (29-06-2012)“…IN THE NEOCORTEX, NEURONAL NITRIC OXIDE (NO) SYNTHASE (NNOS) IS ESSENTIALLY EXPRESSED IN TWO CLASSES OF GABAERGIC NEURONS: type I neurons displaying high…”
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18
Identification of sleep-promoting neurons in vitro
Published in Nature (London) (27-04-2000)“…The neurons responsible for the onset of sleep are thought to be located in the preoptic area and more specifically, in the ventrolateral preoptic nucleus…”
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Classification of Fusiform Neocortical Interneurons Based on Unsupervised Clustering
Published in Proceedings of the National Academy of Sciences - PNAS (23-05-2000)“…A classification of fusiform neocortical interneurons (n = 60) was performed with an unsupervised cluster analysis based on the comparison of multiple…”
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Molecular and Physiological Diversity of Cortical Nonpyramidal Cells
Published in The Journal of neuroscience (15-05-1997)“…The physiological and molecular features of nonpyramidal cells were investigated in acute slices of sensory-motor cortex using whole-cell recordings combined…”
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