Search Results - "ROSENZWEIG, A"

Defining the pathway to insulin-like growth factor system targeting in cancer by Rosenzweig, Steven A., Atreya, Hanudatta S.

“…The insulin-like growth factors (IGFs; IGF-1 and IGF-2) play central roles in cell growth, differentiation, survival, transformation and metastasis. The…”
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Impact of metal exposure on environmentally isolated Serratia marcescens’ growth, oxidative-stress resistance, biofilm formation, and proliferation in eukaryotic co-culture models by Adedoyin, Folasade T., Sridhar, Balaji Bhaskar Maruthi, Rosenzweig, Jason A.

“…Environmental metals can be noxious to the surrounding biota, indirectly impact freshwater habitats, and also impact microbiological communities. In this…”
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The Continuing Evolution of Insulin-like Growth Factor Signaling [version 1; peer review: 4 approved] by Rosenzweig, Steven A

“…The insulin-like growth factors (IGFs; IGF1/IGF2), known for their regulation of cell and organismal growth and development, are evolutionarily conserved…”
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Guggulsterone for Chemoprevention of Cancer by Shishodia, Shishir, Azu, Nkem, Rosenzweig, Jason A, Jackson, Desiree A

“…Guggulsterone [4, 17(20)-pregnadiene-3, 16-dione] is a plant sterol derived from the gum resin of the tree Commiphora wightii. The gum resin of the guggul tree…”
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Nitrosopumilus maritimus genome reveals unique mechanisms for nitrification and autotrophy in globally distributed marine crenarchaea by Walker, C. B., de la Torre, J. R., Klotz, M. G., Urakawa, H., Pinel, N., Arp, D. J., Brochier-Armanet, C., Chain, P. S. G., Chan, P. P., Gollabgir, A., Hemp, J., Hügler, M., Karr, E. A., Könneke, M., Shin, M., Lawton, T. J., Lowe, T., Martens-Habbena, W., Sayavedra-Soto, L. A., Lang, D., Sievert, S. M., Rosenzweig, A. C., Manning, G., Stahl, D. A., Karl, David

“…Ammonia-oxidizing archaea are ubiquitous in marine and terrestrial environments and now thought to be significant contributors to carbon and nitrogen cycling…”
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Convergent signal transduction pathways controlling cardiomyocyte survival and function: the role of PI 3-kinase and Akt by Matsui, Takashi, Rosenzweig, Anthony

“…Effective cardioprotection in clinical settings requires not only cardiomyocyte survival but also preservation of fonction. Multiple growth factors protect the…”
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Regulation of invasive behavior by vascular endothelial growth factor is HEF1-dependent by Lucas, J T, Salimath, B P, Slomiany, M G, Rosenzweig, S A

“…We previously reported a vascular endothelial growth factor (VEGF) autocrine loop in head and neck squamous cell carcinoma (HNSCC) cell lines, supporting a…”
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Comparison of Kidney Injury Molecule-1 and Other Nephrotoxicity Biomarkers in Urine and Kidney Following Acute Exposure to Gentamicin, Mercury, and Chromium by Zhou, Yuzhao, Vaidya, Vishal S., Brown, Ronald P., Zhang, Jun, Rosenzweig, Barry A., Thompson, Karol L., Miller, Terry J., Bonventre, Joseph V., Goering, Peter L.

“…Sensitive biomarkers are needed to detect kidney injury at the earliest stages. The objective of this study was to determine whether the appearance of kidney…”
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The peroxidase PRDX1 inhibits the activated phenotype in mammary fibroblasts through regulating c-Jun N-terminal kinases by Jezierska-Drutel, Agnieszka, Attaran, Shireen, Hopkins, Barbara L, Skoko, John J, Rosenzweig, Steven A, Neumann, Carola A

“…Reactive oxygen species (ROS), including hydrogen peroxide, drive differentiation of normal fibroblasts into activated fibroblasts, which can generate high…”
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Copper Delivery by Metallochaperone Proteins by Rosenzweig, Amy C

“…Copper is an essential element in all living organisms, serving as a cofactor for many important proteins and enzymes. Metallochaperone proteins deliver copper…”
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Spaceflight and modeled microgravity effects on microbial growth and virulence by Rosenzweig, Jason A, Abogunde, Ohunene, Thomas, Kayama, Lawal, Abidat, Nguyen, Y-Uyen, Sodipe, Ayodotun, Jejelowo, Olufisayo

“…For unsuspecting bacteria, the difference between life and death depends upon efficient and specific responses to various stressors. Facing a much larger…”
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The tumor suppressor capability of p53 is dependent on non-muscle myosin IIA function in head and neck cancer by Coaxum, Sonya D, Tiedeken, Jessica, Garrett-Mayer, Elizabeth, Myers, Jeffrey, Rosenzweig, Steven A, Neskey, David M

“…Over 300,000 patients develop squamous cell carcinoma of the head and neck (HNSCC) worldwide with 25-30% of patients ultimately dying from their disease…”
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Evaluating the Utility of Proteomics for the Identification of Circulating Pharmacodynamic Biomarkers of IFNβ‐1a Biologics by Hyland, Paula L., Chekka, Lakshmi Manasa S., Samarth, Deepti P., Rosenzweig, Barry A., Decker, Erica, Mohamed, Esraa G., Guo, Yan, Matta, Murali K., Sun, Qin, Wheeler, William, Sanabria, Carlos, Weaver, James L., Schrieber, Sarah J., Florian, Jeffry, Wang, Yow‐Ming, Strauss, David G.

“…Proteomics has the potential to identify pharmacodynamic (PD) biomarkers for similarity assessment of proposed biosimilars without relying on clinical efficacy…”
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Comparative profile of commercially available urinary biomarkers in preclinical drug-induced kidney injury and recovery in rats by Rouse, Rodney L., Zhang, Jun, Stewart, Sharron R., Rosenzweig, Barry A., Espandiari, Parvaneh, Sadrieh, Nakissa K.

“…We designed a study to provide reversibility and comparative injury data for several candidate urinary biomarkers of kidney injury in the United States Food…”
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An ultra-stable redox-controlled self-assembling polypeptide nanotube for targeted imaging and therapy in cancer by Asampille, Gitanjali, Verma, Brijesh Kumar, Swain, Monalisa, Shettar, Abhijith, Rosenzweig, Steven A, Kondaiah, Paturu, Atreya, Hanudatta S

“…We introduce a self-assembling polypeptide-based nanotube system having the ability to specifically target cancer cells. The nanotubes target the cancer cell…”
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Acquired Resistance to Drugs Targeting Tyrosine Kinases by Rosenzweig, Steven A

“…Resistance to chemotherapeutic drugs exemplifies the greatest hindrance to effective treatment of cancer patients. The molecular mechanisms responsible have…”
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Hypoxia-inducible factor-1-dependent and -independent regulation of insulin-like growth factor-1-stimulated vascular endothelial growth factor secretion by Slomiany, Mark G, Rosenzweig, Steven A

“…Hypoxia-induced stress plays a central role in retinal vascular disease and cancer. Increased hypoxia-inducible factor-1 alpha (Hif-1 alpha) expression leads…”
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Interaction between the RNA-dependent ATPase and poly(A) polymerase subunits of the TRAMP complex is mediated by short peptides and important for snoRNA processing by Losh, Jillian S, King, Alejandra Klauer, Bakelar, Jeremy, Taylor, Lacy, Loomis, John, Rosenzweig, Jason A, Johnson, Sean J, van Hoof, Ambro

“…The RNA exosome is one of the main 3′ to 5′ exoribonucleases in eukaryotic cells. Although it is responsible for degradation or processing of a wide variety of…”
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Vimentin and Non-Muscle Myosin IIA are Members of the Neural Precursor Cell Expressed Developmentally Down-Regulated 9 (NEDD9) Interactome in Head and Neck Squamous Cell Carcinoma Cells by Semelakova, Martina, Grauzam, Stèphane, Betadthunga, Prabhakar, Tiedeken, Jessica, Coaxum, Sonya, Neskey, David M., Rosenzweig, Steven A.

“…Here we demonstrate an interaction between neural precursor cell expressed, developmentally-downregulated 9 (NEDD9) and the cytoskeletal proteins vimentin and…”
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Pathogenesis of Y. enterocolitica and Y. pseudotuberculosis in Human Yersiniosis by Chopra, Ashok K., Kirtley, Michelle L., Rosenzweig, Jason A., Galindo, Cristi L.

“…Yersiniosis is a food-borne illness that has become more prevalent in recent years due to human transmission via the fecal-oral route and prevalence in farm…”
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