Search Results - "ROSENKRANZ, J"
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Peripheral anti-inflammatory cytokine Interleukin-10 treatment mitigates interleukin-1β - induced anxiety and sickness behaviors in adult male rats
Published in Behavioural brain research (17-10-2019)“…•IL-1β caused sickness-like behavior and anxiety-like behavior.•IL-10 alone did not cause acute sickness-like behavior.•IL-10 alone caused anxiety-like…”
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Shifts in Medial Orbitofrontal Cortex Activity from Adolescence to Adulthood
Published in Cerebral cortex (New York, N.Y. 1991) (22-01-2022)“…Abstract Adolescents are characterized by a propensity for risky and impulsive behaviors, likely due to immature frontostriatal circuits. The medial…”
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Effects of Peripheral Immune Challenge on In Vivo Firing of Basolateral Amygdala Neurons in Adult Male Rats
Published in Neuroscience (15-10-2018)“…•IL-1β (1 µg, i.p.) induced sickness-like behavior in adult male Sprague–Dawley rats.•It increased the firing rate in the BLA complex acutely with a change in…”
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Repeated Restraint Stress Alters Small Conductance Calcium‐activated Potassium Channel (SK) Expression in Rat Basolateral Amygdala Neurons in Sex‐dependent Manner
Published in The FASEB journal (01-05-2022)“…Mood disorders disproportionally affect women more than men. The basolateral amygdala (BLA) is critical for the expression of fear and anxiety‐like behaviors…”
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Effects of Repeated Stress on Excitatory Drive of Basal Amygdala Neurons In Vivo
Published in Neuropsychopharmacology (New York, N.Y.) (01-08-2013)“…Chronic stress leads to heightened affective behaviors, and can precipitate the emergence of depression and anxiety. These disorders are associated with…”
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Maturation of amygdala inputs regulate shifts in social and fear behaviors: A substrate for developmental effects of stress
Published in Neuroscience and biobehavioral reviews (01-06-2021)“…•Development is characterized by changes in fear learning and social behavior.•Adolescence is a period of heightened sensitivity to stressors.•Behavioral…”
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Disruptive effects of repeated stress on basolateral amygdala neurons and fear behavior across the estrous cycle in rats
Published in Scientific reports (23-08-2019)“…Stress is a precipitating factor in depression and anxiety disorders. Patients with these disorders often show amygdala abnormalities. The basolateral amygdala…”
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Effects of Repeated Stress on Age-Dependent GABAergic Regulation of the Lateral Nucleus of the Amygdala
Published in Neuropsychopharmacology (New York, N.Y.) (01-08-2016)“…The adolescent age is associated with lability of mood and emotion. The onset of depression and anxiety disorders peaks during adolescence and there are…”
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Chronic Stress Causes Amygdala Hyperexcitability in Rodents
Published in Biological psychiatry (1969) (15-06-2010)“…Background Chronic stress is a major health concern, often leading to depression, anxiety, or when severe enough, posttraumatic stress disorder. While many…”
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Repeated restraint stress increases basolateral amygdala neuronal activity in an age-dependent manner
Published in Neuroscience (13-12-2012)“…Highlights ► Repeated restraint increased BLA neuronal activity in an age-dependent manner. ► Repeated restraint increased the number of active BLA neurons in…”
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Repeated restraint stress enhances cue-elicited conditioned freezing and impairs acquisition of extinction in an age-dependent manner
Published in Behavioural brain research (01-07-2013)“…•Repeated restraint enhanced conditioned freezing in both adolescent and adult rats.•Repeated restraint impaired extinction of fear conditioning in adolescent…”
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The medial orbitofrontal cortex governs reward-related circuits in an age-dependent manner
Published in Cerebral cortex (New York, N.Y. 1991) (20-02-2023)“…Abstract Nucleus accumbens (NAc) neurons integrate excitatory inputs from cortical and limbic structures, contributing to critical cognitive functions,…”
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Sex- and Estrus-Dependent Differences in Rat Basolateral Amygdala
Published in The Journal of neuroscience (01-11-2017)“…Depression and anxiety are diagnosed almost twice as often in women, and the symptomology differs in men and women and is sensitive to sex hormones. The…”
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Distinct Effects of Repeated Restraint Stress on Basolateral Amygdala Neuronal Membrane Properties in Resilient Adolescent and Adult Rats
Published in Neuropsychopharmacology (New York, N.Y.) (01-08-2014)“…Severe and repeated stress has damaging effects on health, including initiation of depression and anxiety. Stress that occurs during development has…”
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Post-weaning social isolation impairs observational fear conditioning
Published in Behavioural brain research (01-04-2013)“…► Freezing response is acquired by observation of tone-shock pairings to conspecific. ► Correlated with orientation toward conspecific during conditioning. ►…”
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Repeated restraint stress exerts different impact on structure of neurons in the lateral and basal nuclei of the amygdala
Published in Neuroscience (29-08-2013)“…Highlights • Repeated restraint stress increases spine number in the basolateral amygdala complex. • Increased spines found on principal neurons in lateral…”
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An intra-amygdala circuit specifically regulates social fear learning
Published in Nature neuroscience (01-03-2017)“…Effective social behavior requires comprehension of social cues and use of those cues to guide behavior. This study uncovers an amygdala circuit that is…”
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Repeated stress induces a pro-inflammatory state, increases amygdala neuronal and microglial activation, and causes anxiety in adult male rats
Published in Brain, behavior, and immunity (01-02-2020)“…•Repeated social defeat stress (RSDS) induces anxiety-like behavior.•RSDS increases dual negative but decreases dual positive, CD4+ and regulatory…”
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Social Isolation During Postweaning Development Causes Hypoactivity of Neurons in the Medial Nucleus of the Male Rat Amygdala
Published in Neuropsychopharmacology (New York, N.Y.) (01-06-2016)“…Children exposed to neglect or social deprivation are at heightened risk for psychiatric disorders and abnormal social patterns as adults. There is also…”
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The Prefrontal Cortex Regulates Lateral Amygdala Neuronal Plasticity and Responses to Previously Conditioned Stimuli
Published in The Journal of neuroscience (03-12-2003)“…The amygdala plays a role in learning and memory processes that involve an emotional component. However, neural structures that regulate these…”
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