Search Results - "ROSENBLUTH, M"

Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages by Rosenbluth, Jennifer M., Schackmann, Ron C. J., Gray, G. Kenneth, Selfors, Laura M., Li, Carman Man-Chung, Boedicker, Mackenzie, Kuiken, Hendrik J., Richardson, Andrea, Brock, Jane, Garber, Judy, Dillon, Deborah, Sachs, Norman, Clevers, Hans, Brugge, Joan S.

“…Recently, organoid technology has been used to generate a large repository of breast cancer organoids. Here we present an extensive evaluation of the ability…”
Get full text

A human breast atlas integrating single-cell proteomics and transcriptomics by Gray, G. Kenneth, Li, Carman Man-Chung, Rosenbluth, Jennifer M., Selfors, Laura M., Girnius, Nomeda, Lin, Jia-Ren, Schackmann, Ron C.J., Goh, Walter L., Moore, Kaitlin, Shapiro, Hana K., Mei, Shaolin, D’Andrea, Kurt, Nathanson, Katherine L., Sorger, Peter K., Santagata, Sandro, Regev, Aviv, Garber, Judy E., Dillon, Deborah A., Brugge, Joan S.

“…The breast is a dynamic organ whose response to physiological and pathophysiological conditions alters its disease susceptibility, yet the specific effects of…”
Get full text

The Fiscal Politics of Immigration: Expert Information and Concerns over Fiscal Drain by Kage, Rieko, Rosenbluth, Frances M., Tanaka, Seiki

“…Recent studies find that fiscal concerns strongly condition public attitudes toward immigration. To what extent do expert cues affect these worries? Original…”
Get full text

Human embryos secrete microRNAs into culture media—a potential biomarker for implantation by Rosenbluth, Evan M., M.D, Shelton, Dawne N., Ph.D, Wells, Lindsay M., M.D, Sparks, Amy E.T., Ph.D, Van Voorhis, Bradley J., M.D

“…Objective To determine whether human blastocysts secrete microRNA (miRNAs) into culture media and whether these reflect embryonic ploidy status and can predict…”
Get full text

p73 Is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network by Marshall, Clayton B., Mays, Deborah J., Beeler, J. Scott, Rosenbluth, Jennifer M., Boyd, Kelli L., Santos Guasch, Gabriela L., Shaver, Timothy M., Tang, Lucy J., Liu, Qi, Shyr, Yu, Venters, Bryan J., Magnuson, Mark A., Pietenpol, Jennifer A.

“…We report that p73 is expressed in multiciliated cells (MCCs), is required for MCC differentiation, and directly regulates transcriptional modulators of…”
Get full text

Varieties of Public Attitudes toward Immigration: Evidence from Survey Experiments in Japan by Kage, Rieko, Rosenbluth, Frances M., Tanaka, Seiki

“…What factors shape attitudes toward immigration? Previous studies have typically debated whether citizens oppose immigration more for economic or cultural…”
Get full text

MicroRNA expression in the human blastocyst by Rosenbluth, Evan M., M.D, Shelton, Dawne N., Ph.D, Sparks, Amy E.T., Ph.D, Devor, Eric, Ph.D, Christenson, Lane, Ph.D, Van Voorhis, Bradley J., M.D

“…Objective To determine the most highly expressed microRNAs (miRNAs) in human blastocysts and to compare miRNAs in euploid versus aneuploid embryos and in male…”
Get full text

mTOR regulates autophagy-associated genes downstream of p73 by Rosenbluth, Jennifer M., Pietenpol, Jennifer A.

“…The p53 family consists of three transcription factors, p53, p63, and p73 that share domain architecture and sequence identity. The mTOR (mammalian Target of…”
Get full text

Identification of Markers of Taxane Sensitivity Using Proteomic and Genomic Analyses of Breast Tumors from Patients Receiving Neoadjuvant Paclitaxel and Radiation by Bauer, Joshua A, Chakravarthy, A Bapsi, Rosenbluth, Jennifer M, Mi, Deming, Seeley, Erin H, De Matos Granja-Ingram, Nara, Olivares, Maria G, Kelley, Mark C, Mayer, Ingrid A, Meszoely, Ingrid M, Means-Powell, Julie A, Johnson, Kimberly N, Tsai, Chiaojung Jillian, Ayers, Gregory D, Sanders, Melinda E, Schneider, Robert J, Formenti, Silvia C, Caprioli, Richard M, Pietenpol, Jennifer A

“…Purpose: To identify molecular markers of pathologic response to neoadjuvant paclitaxel/radiation treatment, protein and gene expression profiling were done on…”
Get full text

A Gene Signature-Based Approach Identifies mTOR as a Regulator of p73 by Rosenbluth, Jennifer M., Mays, Deborah J., Pino, Maria F., Tang, Luo Jia, Pietenpol, Jennifer A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Poloidal Flow Driven by Ion-Temperature-Gradient Turbulence in Tokamaks by Rosenbluth, M. N., Hinton, F. L.

Get full text

Clinical outcomes of de novo metastatic HER2-positive inflammatory breast cancer by Garrido-Castro, Ana C., Regan, Meredith M., Niman, Samuel M., Nakhlis, Faina, Remolano, Claire, Rosenbluth, Jennifer M., Block, Caroline, Warren, Laura E., Bellon, Jennifer R., Yeh, Eren, Harrison, Beth T., Troll, Elizabeth, Lin, Nancy U., Tolaney, Sara M., Overmoyer, Beth, Lynce, Filipa

“…Inflammatory breast cancer (IBC) is a rare, aggressive form of breast cancer that presents as de novo metastatic disease in 20–30% of cases, with one-third of…”
Get full text

Magnetic resonance imaging insights from active surveillance of women with ductal carcinoma in situ by Greenwood, Heather I., Maldonado Rodas, Cristian K., Freimanis, Rita I., Glencer, Alexa C., Miller, Phoebe N., Mukhtar, Rita A., Brabham, Case, Yau, Christina, Rosenbluth, Jennifer M., Hirst, Gillian L., Campbell, Michael J., Borowsky, Alexander, Hylton, Nola, Esserman, Laura J., Basu, Amrita

“…New approaches are needed to determine which ductal carcinoma in situ (DCIS) is at high risk for progression to invasive ductal carcinoma (IDC). We…”
Get full text

Differential regulation of the p73 cistrome by mammalian target of rapamycin reveals transcriptional programs of mesenchymal differentiation and tumorigenesis by Rosenbluth, Jennifer M, Mays, Deborah J, Jiang, Aixiang, Shyr, Yu, Pietenpol, Jennifer A

“…The transcription factor p73 plays critical roles during development and tumorigenesis. It exhibits sequence identity and structural homology with p53, and can…”
Get full text

Modulus-dependent macrophage adhesion and behavior by Irwin, E. F., Saha, K., Rosenbluth, M., Gamble, L. J., Castner, D. G., Healy, K. E.

“…Macrophage attachment and activation to implanted materials is crucial in determining the extent of acute and chronic inflammation, and biomaterials…”
Get full text

Analyzing cell mechanics in hematologic diseases with microfluidic biophysical flow cytometry by Rosenbluth, Michael J, Lam, Wilbur A, Fletcher, Daniel A

“…Pathological processes in hematologic diseases originate at the single-cell level, often making measurements on individual cells more clinically relevant than…”
Get more information

ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy by Eby, Kathryn G, Rosenbluth, Jennifer M, Mays, Deborah J, Marshall, Clayton B, Barton, Christopher E, Sinha, Seema, Johnson, Kimberly N, Tang, Luojia, Pietenpol, Jennifer A

“…Autophagy is characterized by the sequestration of cytoplasm and organelles into multimembrane vesicles and subsequent degradation by the cell's lysosomal…”
Get full text

Evaluation of p63 and p73 antibodies for cross-reactivity by Rosenbluth, Jennifer M., Johnson, Kimberly, Tang, Luojia, Triplett, Tracy, Pietenpol, Jennifer A.

“…The tumor suppressor p53 is commonly mutated in human cancers.  However, two homologs of p53, p63 and p73, are frequently over-expressed in tumors and are…”
Get full text

A large peptidome dataset improves HLA class I epitope prediction across most of the human population by Sarkizova, Siranush, Klaeger, Susan, Le, Phuong M., Li, Letitia W., Oliveira, Giacomo, Keshishian, Hasmik, Hartigan, Christina R., Zhang, Wandi, Braun, David A., Ligon, Keith L., Bachireddy, Pavan, Zervantonakis, Ioannis K., Rosenbluth, Jennifer M., Ouspenskaia, Tamara, Law, Travis, Justesen, Sune, Stevens, Jonathan, Lane, William J., Eisenhaure, Thomas, Lan Zhang, Guang, Clauser, Karl R., Hacohen, Nir, Carr, Steven A., Wu, Catherine J., Keskin, Derin B.

“…Prediction of HLA epitopes is important for the development of cancer immunotherapies and vaccines. However, current prediction algorithms have limited…”
Get full text

Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids by Dekkers, Johanna F., van Vliet, Esmée J., Sachs, Norman, Rosenbluth, Jennifer M., Kopper, Oded, Rebel, Heggert G., Wehrens, Ellen J., Piani, Carol, Visvader, Jane E., Verissimo, Carla S., Boj, Sylvia F., Brugge, Joan S., Clevers, Hans, Rios, Anne C.

“…Organoid technology has revolutionized the study of human organ development, disease and therapy response tailored to the individual. Although detailed…”
Get full text