Search Results - "ROSENBERG, Gary A"
-
1
Neurological Diseases in Relation to the Blood–Brain Barrier
Published in Journal of Cerebral Blood Flow & Metabolism (01-07-2012)“…Disruption of the blood–brain barrier (BBB) has an important part in cellular damage in neurological diseases, including acute and chronic cerebral ischemia,…”
Get full text
Book Review Journal Article -
2
Extracellular matrix inflammation in vascular cognitive impairment and dementia
Published in Clinical science (1979) (01-03-2017)“…Vascular cognitive impairment and dementia (VCID) include a wide spectrum of chronic manifestations of vascular disease related to large vessel strokes and…”
Get more information
Journal Article -
3
Blood-Brain Barrier Breakdown in Acute and Chronic Cerebrovascular Disease
Published in Stroke (1970) (01-11-2011)“…Disruptions of the blood-brain barrier (BBB) and edema formation both play key roles in the development of neurological dysfunction in acute and chronic…”
Get full text
Journal Article -
4
Matrix metalloproteinases as therapeutic targets for stroke
Published in Brain research (14-10-2015)“…Abstract Matrix metalloproteinases (MMPs) are important in injury and recovery in ischemic injury. They are proteolytic enzymes that degrade all components of…”
Get full text
Journal Article -
5
Neuroinflammation: friend and foe for ischemic stroke
Published in Journal of neuroinflammation (10-07-2019)“…Stroke, the third leading cause of death and disability worldwide, is undergoing a change in perspective with the emergence of new ideas on neurodegeneration…”
Get full text
Journal Article -
6
MRI measurements of Blood-Brain Barrier function in dementia: A review of recent studies
Published in Neuropharmacology (15-05-2018)“…Blood-brain barrier (BBB) separates the systemic circulation and the brain, regulating transport of most molecules to protect the brain microenvironment…”
Get full text
Journal Article -
7
Matrix metalloproteinases and their multiple roles in neurodegenerative diseases
Published in Lancet neurology (01-02-2009)“…Summary Matrix metalloproteinases (MMPs) and proteins containing a disintegrin and metalloproteinase domain (ADAM) are important in neuroinflammation, and…”
Get full text
Journal Article -
8
Inflammation and White Matter Damage in Vascular Cognitive Impairment
Published in Stroke (1970) (01-03-2009)“…Vascular cognitive impairment is a term used to describe a heterogeneous group of diseases, including large vessel disease with strategic single and multiple…”
Get full text
Conference Proceeding Journal Article -
9
Understanding aging effects on brain ischemia
Published in Neurobiology of disease (01-06-2019)Get full text
Journal Article -
10
Multimodal Markers of Inflammation in the Subcortical Ischemic Vascular Disease Type of Vascular Cognitive Impairment
Published in Stroke (1970) (01-05-2014)Get full text
Journal Article -
11
Long-Term Blood–Brain Barrier Permeability Changes in Binswanger Disease
Published in Stroke (1970) (01-09-2015)“…BACKGROUND AND PURPOSE—The blood–brain barrier (BBB) is disrupted in small vessel disease patients with lacunes and white matter hyperintensities (WMHs). The…”
Get full text
Journal Article -
12
MMP-mediated disruption of claudin-5 in the blood-brain barrier of rat brain after cerebral ischemia
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2011)“…The blood-brain barrier (BBB) has become a major focus of attention in cerebral pathophysiology and disease progression in the central nervous system…”
Get more information
Journal Article -
13
Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat
Published in Journal of cerebral blood flow and metabolism (01-04-2007)“…Matrix metalloproteinases (MMPs) disrupt the blood—brain barrier (BBB) during reperfusion. Occludin and claudins are recently described tight junction proteins…”
Get full text
Journal Article -
14
Vasogenic edema due to tight junction disruption by matrix metalloproteinases in cerebral ischemia
Published in Neurosurgical focus (15-05-2007)“…Cerebral ischemia causes cell swelling and breakdown of the blood-brain barrier (BBB). Cytotoxic edema results from energy failure, and vasogenic edema occurs…”
Get full text
Journal Article -
15
Vascular tight junction disruption and angiogenesis in spontaneously hypertensive rat with neuroinflammatory white matter injury
Published in Neurobiology of disease (01-06-2018)“…Vascular cognitive impairment is a major cause of dementia caused by chronic hypoxia, producing progressive damage to white matter (WM) secondary to…”
Get full text
Journal Article -
16
Hypoxia-Induced Neuroinflammatory White-Matter Injury Reduced by Minocycline in SHR/SP
Published in Journal of cerebral blood flow and metabolism (01-07-2015)“…Hypertensive small vessel disease is a major cause of vascular cognitive impairment (VCI). Spontaneously hypertensive/stroke prone rats (SHR/SP) with…”
Get full text
Journal Article -
17
Matrix metalloproteinases in neuroinflammation
Published in Glia (01-09-2002)“…Matrix metalloproteinases (MMPs) are a gene family of neutral proteases that are important in normal development, wound healing, and a wide variety of…”
Get full text
Journal Article -
18
Barriers of the CNS transfer rate dynamics in patients with vascular cognitive impairment and dementia
Published in Frontiers in aging neuroscience (25-09-2024)“…Advances in MRI techniques enable cerebral barrier transfer rates (K ) measurement in patients with vascular cognitive impairment and dementia (VCID). However,…”
Get full text
Journal Article -
19
Shared Inflammatory Pathology of Stroke and COVID-19
Published in International journal of molecular sciences (05-05-2022)“…Though COVID-19 is primarily characterized by symptoms in the periphery, it can also affect the central nervous system (CNS). This has been established by the…”
Get full text
Journal Article -
20
Consensus statement for diagnosis of subcortical small vessel disease
Published in Journal of Cerebral Blood Flow & Metabolism (01-01-2016)“…Vascular cognitive impairment (VCI) is the diagnostic term used to describe a heterogeneous group of sporadic and hereditary diseases of the large and small…”
Get full text
Journal Article Book Review