Search Results - "ROSEN, M. D"

Hohlraum Reheating from Burning NIF Implosions by Rubery, M S, Rosen, M D, Aybar, N, Landen, O L, Divol, L, Young, C V, Weber, C, Hammer, J, Moody, J D, Moore, A S, Kritcher, A L, Zylstra, A B, Hurricane, O, Pak, A E, MacLaren, S, Zimmerman, G, Harte, J, Woods, T

“…As fusion experiments at the National Ignition Facility (NIF) approach and exceed breakeven, energy from the burning capsule is predicted to couple to the gold…”
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Development of Improved Radiation Drive Environment for High Foot Implosions at the National Ignition Facility by Hinkel, D E, Berzak Hopkins, L F, Ma, T, Ralph, J E, Albert, F, Benedetti, L R, Celliers, P M, Döppner, T, Goyon, C S, Izumi, N, Jarrott, L C, Khan, S F, Kline, J L, Kritcher, A L, Kyrala, G A, Nagel, S R, Pak, A E, Patel, P, Rosen, M D, Rygg, J R, Schneider, M B, Turnbull, D P, Yeamans, C B, Callahan, D A, Hurricane, O A

“…Analyses of high foot implosions show that performance is limited by the radiation drive environment, i.e., the hohlraum. Reported here are significant…”
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Targeted delivery of cytotoxic proteins to prostate cancer via conjugation to small molecule urea-based PSMA inhibitors by Rogers, O. C., Rosen, D. M., Antony, L., Harper, H. M., Das, D., Yang, X., Minn, I., Mease, R. C., Pomper, M. G., Denmeade, S. R.

“…Prostate cancer cells are characterized by a remarkably low proliferative rate and the production of high levels of prostate-specific proteases. Protein-based…”
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Deletion of p53 in human mammary epithelial cells causes chromosomal instability and altered therapeutic response by Weiss, M B, Vitolo, M I, Mohseni, M, Rosen, D M, Denmeade, S R, Park, B H, Weber, D J, Bachman, K E

“…The TP53 tumor suppressor gene is the most commonly mutated gene in human cancers. To evaluate the biological and clinical relevance of p53 loss, human somatic…”
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Plasma-based beam combiner for very high fluence and energy by Kirkwood, R. K., Turnbull, D. P., Chapman, T., Wilks, S. C., Rosen, M. D., London, R. A., Pickworth, L. A., Dunlop, W. H., Moody, J. D., Strozzi, D. J., Michel, P. A., Divol, L., Landen, O. L., MacGowan, B. J., Van Wonterghem, B. M., Fournier, K. B., Blue, B. E.

“…Extreme optical fluences, much beyond the damage threshold of conventional optics, are of interest for a range of high-energy-density physics applications…”
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Phase I study of the orally administered butyrate prodrug, tributyrin, in patients with solid tumors by CONLEY, B. A, EGORIN, M. J, TAIT, N, ROSEN, D. M, SAUSVILLE, E. A, DOVER, G, FRAM, R. J, VAN ECHO, D. A

“…Butyrates have been studied as cancer differentiation agents in vitro and as a treatment for hemoglobinopathies. Tributyrin, a triglyceride with butyrate…”
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Creation of hot radiation environments in laser-driven targets by Hinkel, D E, Schneider, M B, Young, B K, Langdon, A B, Williams, E A, Rosen, M D, Suter, L J

“…A hot radiation environment, produced by maximizing laser-energy deposition into a small, high- "can," is a platform being developed for investigations of…”
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The combination of insulin-like growth factor I and insulin-like growth factor-binding protein-3 reduces insulin requirements in insulin-dependent type 1 diabetes : Evidence for in vivo biological activity by CLEMMONS, D. R, MOSES, A. C, MCKAY, M. J, SOMMER, A, ROSEN, D. M, RUCKLE, J

“…Insulin-like growth factor-I (IGF-I) enhances insulin action in normal subjects and in patients with both type 1 and 2 diabetes; however, its administration is…”
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Measurement of the absolute Hohlraum-Wall albedo under ignition foot drive conditions by JONES, O. S, GLENZER, S. H, ROSEN, M. D, WALLACE, R. J, WEBER, F. A, SUTER, L. J, TURNER, R. E, CAMPBELL, K. M, DEWALD, E. L, HAMMEL, B. A, HAMMER, J. H, KAUFFMAN, R. L, LANDEN, O. L

“…We present measurements of the absolute albedos of hohlraums made from gold or from high-Z mixtures. The measurements are performed over the range of radiation…”
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Metabolism of 17-(allylamino)-17-demethoxygeldanamycin (NSC 330507) by murine and human hepatic preparations by EGORIN, M. J, ROSEN, D. M, WOLFF, J. H, CALLERY, P. S, MUSSER, S. M, EISEMAN, J. L

“…17-(Allylamino)-17-demethoxygeldanamycin (17AAG), a compound that is proposed for clinical development, shares the ability of geldanamycin to bind to heat…”
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Phase I Study of Paclitaxel in Combination With a Multidrug Resistance Modulator, PSC 833 (Valspodar), in Refractory Malignancies by FRACASSO, P. M, WESTERVELDT, P, FEARS, C. A, ROSEN, D. M, ZUHOWSKI, E. G, CAZENAVE, L. A, LITCHMAN, M, EGORIN, M. J

“…To determine the maximum-tolerated dose (MTD), dose-limiting toxicity (DLT), and pharmacokinetics of paclitaxel when given with PSC 833 (valspodar) to patients…”
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Cartilage-inducing factor-A. Apparent identity to transforming growth factor-beta by Seyedin, S M, Thompson, A Y, Bentz, H, Rosen, D M, McPherson, J M, Conti, A, Siegel, N R, Galluppi, G R, Piez, K A

“…Comparison of the sequence of the N-terminal 30 amino acids of cartilage-inducing factor-A (CIF-A) from bovine demineralized bone with the corresponding…”
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A fragment of the hypophosphatemic factor, MEPE, requires inducible cyclooxygenase-2 to exert potent anabolic effects on normal human marrow osteoblast precursors by Nagel, D.E., Khosla, S., Sanyal, A., Rosen, D.M., Kumagai, Y., Riggs, B. Lawrence

“…MEPE, 56.6 kDa protein isolated from tumors associated with hypophosphatemic osteomalacia, increases renal phosphate excretion and is expressed in normal human…”
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Observation of high soft x-ray drive in large-scale hohlraums at the National Ignition Facility by Kline, J L, Glenzer, S H, Olson, R E, Suter, L J, Widmann, K, Callahan, D A, Dixit, S N, Thomas, C A, Hinkel, D E, Williams, E A, Moore, A S, Celeste, J, Dewald, E, Hsing, W W, Warrick, A, Atherton, J, Azevedo, S, Beeler, R, Berger, R, Conder, A, Divol, L, Haynam, C A, Kalantar, D H, Kauffman, R, Kyrala, G A, Kilkenny, J, Liebman, J, Le Pape, S, Larson, D, Meezan, N B, Michel, P, Moody, J, Rosen, M D, Schneider, M B, Van Wonterghem, B, Wallace, R J, Young, B K, Landen, O L, MacGowan, B J

“…The first soft x-ray radiation flux measurements from hohlraums using both a 96 and a 192 beam configuration at the National Ignition Facility have shown high…”
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Cartilage-inducing factor-B is a unique protein structurally and functionally related to transforming growth factor-beta by Seyedin, S.M., Segarini, P.R., Rosen, D.M., Thompson, A.Y., Bentz, H., Graycar, J.

“…Cartilage-inducing factors-A (CIF-A) and -B (CIF-B), purified from bovine bone on the basis of their ability to induce the cartilage phenotype in vitro, are…”
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Multistep redirection by cross-beam power transfer of ultrahigh-power lasers in a plasma by Moody, J. D., Michel, P., Divol, L., Berger, R. L., Bond, E., Bradley, D. K., Callahan, D. A., Dewald, E. L., Dixit, S., Edwards, M. J., Glenn, S., Hamza, A., Haynam, C., Hinkel, D. E., Izumi, N., Jones, O., Kilkenny, J. D., Kirkwood, R. K., Kline, J. L., Kruer, W. L., Kyrala, G. A., Landen, O. L., LePape, S., Lindl, J. D., MacGowan, B. J., Meezan, N. B., Nikroo, A., Rosen, M. D., Schneider, M. B., Strozzi, D. J., Suter, L. J., Thomas, C. A., Town, R. P. J., Widmann, K., Williams, E. A., Atherton, L. J., Glenzer, S. H., Moses, E. I.

“…Laser redirection by cross-beam power transfer in a plasma is an important example of a nonlinear optics process which uses laser–plasma instabilities to one’s…”
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Publisher's Note: Development of improved radiation drive environment for high foot implosions at the National Ignition Facility [Phys. Rev. Lett. 117, 225002 (2016)] by Hinkel, D E, Berzak Hopkins, L F, Ma, T, Ralph, J E, Albert, F, Benedetti, L R, Celliers, P M, Do Ppner, T, Goyon, C S, Izumi, N, Jarrott, L C, Khan, S F, Kline, J L, Kritcher, A L, Kyrala, G A, Nagel, S R, Pak, A E, Patel, P, Rosen, M D, Rygg, J R, Schneider, M B, Turnbull, D P, Yeamans, C B, Callahan, D A, Hurricane, O A

“…This corrects the article DOI: 10.1103/PhysRevLett.117.225002…”
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Ultrafast X-Ray Pulses from Laser-Produced Plasmas by Murnane, Margaret M., Kapteyn, Henry C., Rosen, Mordecai D., Falcone, Roger W.

“…A high-temperature plasma is created when an intense laser pulse is focused onto the surface of a solid. An ultrafast pulse of x-ray radiation is emitted from…”
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The Rosseland Mean Opacity of a Mixture of Gold and Gadolinium at High Temperatures by Orzechowski, TJ, Rosen, MD, Kornblum, HN, Porter, JL, Suter, LJ, Thiessen, AR, Wallace, RJ

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Demonstration of a soft X-ray amplifier by MATTHEWS, D. L, HAGELSTEIN, P. L, CAMPBELL, E. M, HATCHER, C. W, HAWRYLUK, A. M, KAUFFMAN, R. L, PLEASANCE, L. D, RAMBACH, G, SCOFIELD, J. H, STONE, G, WEAVER, T. A, ROSEN, M. D, ECKART, M. J, CEGLIO, N. M, HAZI, A. U, MEDECKI, H, MCGOWAN, B. J, TREBES, J. E, WHITTEN, B. L

“…Observations of amplified spontaneous emission at soft X-ray wavelengths are reported. An optical laser ionized thin foils of selenium to produce a population…”
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