Search Results - "ROSE, Felicity R. A. J"

Translational considerations in injectable cell-based therapeutics for neurological applications: concepts, progress and challenges by Amer, Mahetab H., Rose, Felicity R. A. J., Shakesheff, Kevin M., Modo, Michel, White, Lisa J.

“…Significant progress has been made during the past decade towards the clinical adoption of cell-based therapeutics. However, existing cell-delivery approaches…”
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In Vivo Assessment of Bone Regeneration in Alginate/Bone ECM Hydrogels with Incorporated Skeletal Stem Cells and Single Growth Factors by Gothard, David, Smith, Emma L, Kanczler, Janos M, Black, Cameron R, Wells, Julia A, Roberts, Carol A, White, Lisa J, Qutachi, Omar, Peto, Heather, Rashidi, Hassan, Rojo, Luis, Stevens, Molly M, El Haj, Alicia J, Rose, Felicity R A J, Shakesheff, Kevin M, Oreffo, Richard O C

“…The current study has investigated the use of decellularised, demineralised bone extracellular matrix (ECM) hydrogel constructs for in vivo tissue…”
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Droplet Microfluidic Optimisation Using Micropipette Characterisation of Bio-Instructive Polymeric Surfactants by Henshaw, Charlotte A, Dundas, Adam A, Cuzzucoli Crucitti, Valentina, Alexander, Morgan R, Wildman, Ricky, Rose, Felicity R A J, Irvine, Derek J, Williams, Philip M

“…Droplet microfluidics can produce highly tailored microparticles whilst retaining monodispersity. However, these systems often require lengthy optimisation,…”
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A biomaterials approach to influence stem cell fate in injectable cell-based therapies by Amer, Mahetab H, Rose, Felicity R A J, Shakesheff, Kevin M, White, Lisa J

“…Numerous stem cell therapies use injection-based administration to deliver high-density cell preparations. However, cell retention rates as low as 1% have been…”
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Effect of Sessile Drop Volume on the Wetting Anisotropy Observed on Grooved Surfaces by Yang, Jing, Rose, Felicity R. A. J, Gadegaard, Nikolaj, Alexander, Morgan R

“…This study reports experimental measurements of the water contact angle (WCA) measured on surfaces with grooves of different widths using drop volumes ranging…”
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Recapitulation of tumor heterogeneity and molecular signatures in a 3D brain cancer model with decreased sensitivity to histone deacetylase inhibition by Smith, Stuart J, Wilson, Martin, Ward, Jennifer H, Rahman, Cheryl V, Peet, Andrew C, Macarthur, Donald C, Rose, Felicity R A J, Grundy, Richard G, Rahman, Ruman

“…Physiologically relevant pre-clinical ex vivo models recapitulating CNS tumor micro-environmental complexity will aid development of biologically-targeted…”
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Polymer Microparticles with Defined Surface Chemistry and Topography Mediate the Formation of Stem Cell Aggregates and Cardiomyocyte Function by Alvarez-Paino, Marta, Amer, Mahetab H, Nasir, Aishah, Cuzzucoli Crucitti, Valentina, Thorpe, Jordan, Burroughs, Laurence, Needham, David, Denning, Chris, Alexander, Morgan R, Alexander, Cameron, Rose, Felicity R. A. J

“…Surface-functionalized microparticles are relevant to fields spanning engineering and biomedicine, with uses ranging from cell culture to advanced cell…”
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Stem cells from the dental apical papilla in extracellular matrix hydrogels mitigate inflammation of microglial cells by Tatic, Natalija, Rose, Felicity R. A. J., des Rieux, Anne, White, Lisa J.

“…After spinal cord injury (SCI) chronic inflammation hampers regeneration. Influencing the local microenvironment after SCI may provide a strategy to modulate…”
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Investigating the feasibility of spatially offset Raman spectroscopy for in‐vivo monitoring of bone healing in rat calvarial defect models by Dooley, Max, McLaren, Jane, Rose, Felicity R. A. J., Notingher, Ioan

“…A wide range of biomaterials and tissue‐engineered scaffolds are being investigated to support and stimulate bone healing in animal models. Using phantoms and…”
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Correction to “Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers” by Ruiz-Cantu, Laura, Trindade, Gustavo F, Taresco, Vincenzo, Zhou, Zuoxin, He, Yinfeng, Burroughs, Laurence, Clark, Elizabeth A, Rose, Felicity R. A. J, Tuck, Christopher, Hague, Richard, Roberts, Clive J, Alexander, Morgan, Irvine, Derek J, Wildman, Ricky D

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An in vitro assessment of the thermoreversible PLGA‐PEG‐PLGA copolymer: Implications for Descemet's membrane endothelial keratoplasty by Tint, Naing L., Cheng, Kelvin K. W., Dhillon, Amritpaul S., Keane, Pearse A., Alexander, Philip, Kennedy, David, Chau, David Y. S., Rose, Felicity R. A. J., Allan, Bruce D. S.

“…Background To explore the use of a thermoreversible copolymer gel coating to prevent donor tissue scrolling in Descemet's membrane endothelial keratoplasty…”
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Functional interleukin-4 releasing microparticles impact THP-1 differentiated macrophage phenotype by Lee, I-Ning, Stening, Jasmine Z., Rose, Felicity R. A. J., White, Lisa J.

“…Macrophage cell therapies offer potential treatment in inflammatory diseases due to their ability to mobilize and stimulate their environment. However,…”
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Probing Clostridium difficile Infection in Complex Human Gut Cellular Models by Anonye, Blessing O, Hassall, Jack, Patient, Jamie, Detamornrat, Usanee, Aladdad, Afnan M, Schüller, Stephanie, Rose, Felicity R A J, Unnikrishnan, Meera

“…Interactions of anaerobic gut bacteria, such as , with the intestinal mucosa have been poorly studied due to challenges in culturing anaerobes with the…”
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Controlled release of BMP-2 from a sintered polymer scaffold enhances bone repair in a mouse calvarial defect model by Rahman, Cheryl V., Ben-David, Dror, Dhillon, Amritpaul, Kuhn, Gisela, Gould, Toby W. A., Müller, Ralph, Rose, Felicity R. A. J., Shakesheff, Kevin M., Livne, Erella

“…Sustained and controlled delivery of growth factors, such as bone morphogenetic protein 2 (BMP‐2), from polymer scaffolds has excellent potential for enhancing…”
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Prediction of Drug Response in Breast Cancer Using Integrative Experimental/Computational Modeling by FRIEBOES, Hermann B, EDGERTON, Mary E, FRUEHAUF, John P, ROSE, Felicity R. A. J, WORRALL, Lisa K, GATENBY, Robert A, FERRARI, Mauro, CRISTINI, Vittorio

“…Nearly 30% of women with early-stage breast cancer develop recurrent disease attributed to resistance to systemic therapy. Prevailing models of chemotherapy…”
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Nanofibrous Scaffolds Support a 3D in vitro Permeability Model of the Human Intestinal Epithelium by Patient, Jamie D, Hajiali, Hadi, Harris, Kate, Abrahamsson, Bertil, Tannergren, Christer, White, Lisa J, Ghaemmaghami, Amir M, Williams, Philip M, Roberts, Clive J, Rose, Felicity R A J

“…Advances in drug research not only depend on high throughput screening to evaluate large numbers of lead compounds but also on the development of models which…”
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PLGA/PEG-hydrogel composite scaffolds with controllable mechanical properties by Rahman, Cheryl V., Kuhn, Gisela, White, Lisa J., Kirby, Giles T. S., Varghese, Oommen P., McLaren, Jane S., Cox, Helen C., Rose, Felicity R. A. J., Müller, Ralph, Hilborn, Jöns, Shakesheff, Kevin M.

“…Biodegradable polymer scaffolds have great potential for regenerative medicine applications such as the repair of musculoskeletal tissues. Here, we describe…”
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3D Microfabricated Scaffolds and Microfluidic Devices for Ocular Surface Replacement: a Review by Prina, Elisabetta, Mistry, Pritesh, Sidney, Laura E., Yang, Jing, Wildman, Ricky D., Bertolin, Marina, Breda, Claudia, Ferrari, Barbara, Barbaro, Vanessa, Hopkinson, Andrew, Dua, Harminder S., Ferrari, Stefano, Rose, Felicity R. A. J.

“…In recent years, there has been increased research interest in generating corneal substitutes, either for use in the clinic or as in vitro corneal models. The…”
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Development of bioactive electrospun scaffolds suitable to support skin fibroblasts and release Lucilia sericata maggot excretion/secretion by Giacaman, Annesi G., Styliari, Ioanna D., Taresco, Vincenzo, Pritchard, David, Alexander, Cameron, Rose, Felicity R. A. J.

“…Larval therapy has been reported to be beneficial in the treatment of chronic wounds by promoting granulation tissue formation, due to its antimicrobial…”
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Exploiting Generative Design for 3D Printing of Bacterial Biofilm Resistant Composite Devices by He, Yinfeng, Abdi, Meisam, Trindade, Gustavo F., Begines, Belén, Dubern, Jean‐Frédéric, Prina, Elisabetta, Hook, Andrew L., Choong, Gabriel Y. H., Ledesma, Javier, Tuck, Christopher J., Rose, Felicity R. A. J., Hague, Richard J. M., Roberts, Clive J., De Focatiis, Davide S. A., Ashcroft, Ian A., Williams, Paul, Irvine, Derek J., Alexander, Morgan R., Wildman, Ricky D.

“…As the understanding of disease grows, so does the opportunity for personalization of therapies targeted to the needs of the individual. To bring about a step…”
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