Search Results - "ROSATO, Roberto R"

A comprehensive overview of metaplastic breast cancer: clinical features and molecular aberrations by Reddy, Tejaswini P, Rosato, Roberto R, Li, Xiaoxian, Moulder, Stacy, Piwnica-Worms, Helen, Chang, Jenny C

“…Metaplastic breast cancer (MpBC) is an exceedingly rare breast cancer variant that is therapeutically challenging and aggressive. MpBC is defined by the…”
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A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis by Yao, Fan, Deng, Yalan, Zhao, Yang, Mei, Ying, Zhang, Yilei, Liu, Xiaoguang, Martinez, Consuelo, Su, Xiaohua, Rosato, Roberto R., Teng, Hongqi, Hang, Qinglei, Yap, Shannon, Chen, Dahu, Wang, Yumeng, Chen, Mei-Ju May, Zhang, Mutian, Liang, Han, Xie, Dong, Chen, Xin, Zhu, Hao, Chang, Jenny C., You, M. James, Sun, Yutong, Gan, Boyi, Ma, Li

“…The growing knowledge of ferroptosis has suggested the role and therapeutic potential of ferroptosis in cancer, but has not been translated into effective…”
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Evaluation of anti-PD-1-based therapy against triple-negative breast cancer patient-derived xenograft tumors engrafted in humanized mouse models by Rosato, Roberto R, Dávila-González, Daniel, Choi, Dong Soon, Qian, Wei, Chen, Wen, Kozielski, Anthony J, Wong, Helen, Dave, Bhuvanesh, Chang, Jenny C

“…Breast cancer has been considered not highly immunogenic, and few patients benefit from current immunotherapies. However, new strategies are aimed at changing…”
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A window-of-opportunity trial of the CXCR1/2 inhibitor reparixin in operable HER-2-negative breast cancer by Goldstein, Lori J, Perez, Raymond P, Yardley, Denise, Han, Linda K, Reuben, James M, Gao, Hui, McCanna, Susan, Butler, Beth, Ruffini, Pier Adelchi, Liu, Yi, Rosato, Roberto R, Chang, Jenny C

“…Cancer stem cells (CSCs) are purported to be responsible for tumor initiation, treatment resistance, disease recurrence, and metastasis. CXCR1, one of the…”
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Pharmacological Inhibition of NOS Activates ASK1/JNK Pathway Augmenting Docetaxel-Mediated Apoptosis in Triple-Negative Breast Cancer by Dávila-González, Daniel, Choi, Dong Soon, Rosato, Roberto R, Granados-Principal, Sergio M, Kuhn, John G, Li, Wen-Feng, Qian, Wei, Chen, Wen, Kozielski, Anthony J, Wong, Helen, Dave, Bhuvanesh, Chang, Jenny C

“…Chemoresistance in triple-negative breast cancer (TNBC) is associated with the activation of a survival mechanism orchestrated by the endoplasmic reticulum…”
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β-Lactams Increase the Antibacterial Activity of Daptomycin against Clinical Methicillin-Resistant Staphylococcus aureus Strains and Prevent Selection of Daptomycin-Resistant Derivatives by MEHTA, Shrenik, SINGH, Christopher, PLATA, Konrad B, CHANDA, Palas K, PAUL, Arundhati, RIOSA, Sarah, ROSATO, Roberto R, ROSATO, Adriana E

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A randomized, controlled phase II trial of neoadjuvant ado-trastuzumab emtansine, lapatinib, and nab-paclitaxel versus trastuzumab, pertuzumab, and paclitaxel in HER2-positive breast cancer (TEAL study) by Patel, Tejal A, Ensor, Joe E, Creamer, Sarah L, Boone, Toniva, Rodriguez, Angel A, Niravath, Poly A, Darcourt, Jorge G, Meisel, Jane L, Li, Xiaoxian, Zhao, Jing, Kuhn, John G, Rosato, Roberto R, Qian, Wei, Belcheva, Anna, Schwartz, Mary R, Kaklamani, Virginia G, Chang, Jenny C

“…Neoadjuvant dual human epidermal growth factor receptor (HER2) blockade with trastuzumab and pertuzumab plus paclitaxel leads to an overall pathologic complete…”
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VraSR Two-Component Regulatory System Contributes to mprF-Mediated Decreased Susceptibility to Daptomycin in In Vivo-Selected Clinical Strains of Methicillin-Resistant Staphylococcus aureus by MEHTA, Shrenik, CUIROLO, Arabela X, PLATA, Konrad B, RIOSA, Sarah, SILVERMAN, Jared A, RUBIO, Aileen, ROSATO, Roberto R, ROSATO, Adriana E

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Simultaneous targeting of HER family pro-survival signaling with Pan-HER antibody mixture is highly effective in TNBC: a preclinical trial with PDXs by Reddy, Tejaswini P, Choi, Dong S, Anselme, Ann C, Qian, Wei, Chen, Wen, Lantto, Johan, Horak, Ivan D, Kragh, Michael, Chang, Jenny C, Rosato, Roberto R

“…The human epidermal growth factor receptor (HER) family, notably EGFR, is overexpressed in most triple-negative breast cancer (TNBC) cases and provides cancer…”
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Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy by Sun, Hongguang, Zhu, Xun, Lu, Patrick Y, Rosato, Roberto R, Tan, Wen, Zu, Youli

“…Aptamers are a class of small nucleic acid ligands that are composed of RNA or single-stranded DNA oligonucleotides and have high specificity and affinity for…”
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TCA cycle-mediated generation of ROS is a key mediator for HeR-MRSA survival under β-lactam antibiotic exposure by Rosato, Roberto R, Fernandez, Regina, Paz, Liliana I, Singh, Christopher R, Rosato, Adriana E

“…Methicillin-resistant Staphylococcus aureus (MRSA) is a major multidrug resistant pathogen responsible for several difficult-to-treat infections in humans…”
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Staphylococcus pseudintermedius’s PBP4 Is Directly Associated with the Dissociated Oxacillin and Cefoxitin Phenotype by Gagetti, Paula, Rosato, Roberto R., Rosato, Adriana E.

“…Staphylococcus pseudintermedius is an important pathogen responsible for infections in dogs and in humans. The emergence and dissemination of…”
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Correction to: A window-of-opportunity trial of the CXCR1/2 inhibitor reparixin in operable HER-2-negative breast cancer by Goldstein, Lori J, Perez, Raymond P, Yardley, Denise, Han, Linda K, Reuben, James M, Gao, Hui, McCanna, Susan, Butler, Beth, Ruffini, Pier Adelchi, Liu, Yi, Rosato, Roberto R, Chang, Jenny C

“…An amendment to this paper has been published and can be accessed via the original article…”
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Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells by Rosato, Roberto R, Almenara, Jorge A, Dai, Yun, Grant, Steven

“…Interactions between histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), also known as Apo2 ligand, were…”
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HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway by Liu, Yi, Choi, Dong Soon, Sheng, Jianting, Ensor, Joe E., Liang, Diana Hwang, Rodriguez-Aguayo, Cristian, Polley, Amanda, Benz, Steve, Elemento, Olivier, Verma, Akanksha, Cong, Yang, Wong, Helen, Qian, Wei, Li, Zheng, Granados-Principal, Sergio, Lopez-Berestein, Gabriel, Landis, Melissa D., Rosato, Roberto R., Dave, Bhuvanesh, Wong, Stephen, Marchetti, Dario, Sood, Anil K., Chang, Jenny C.

“…Here, we show that HEMATOLOGICAL AND NEUROLOGICAL EXPRESSED 1-LIKE (HN1L) is a targetable breast cancer stem cell (BCSC) gene that is altered in 25% of whole…”
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Role of histone deacetylase inhibitor-induced reactive oxygen species and DNA damage in LAQ-824/fludarabine antileukemic interactions by Rosato, Roberto R, Almenara, Jorge A, Maggio, Sonia C, Coe, Stefanie, Atadja, Peter, Dent, Paul, Grant, Steven

“…The role of reactive oxygen species (ROS) production on DNA damage and potentiation of fludarabine lethality by the histone deacetylase inhibitor (HDACI)…”
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Targeting of PBP1 by β-lactams determines recA/SOS response activation in heterogeneous MRSA clinical strains by Plata, Konrad B, Riosa, Sarah, Singh, Christopher R, Rosato, Roberto R, Rosato, Adriana E

“…The SOS response, a conserved regulatory network in bacteria that is induced in response to DNA damage, has been shown to be associated with the emergence of…”
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Exposure of clinical MRSA heterogeneous strains to β-lactams redirects metabolism to optimize energy production through the TCA cycle by Keaton, Mignon A, Rosato, Roberto R, Plata, Konrad B, Singh, Christopher R, Rosato, Adriana E

“…Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as one of the most important pathogens both in health care and community-onset infections. The…”
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Fate of Mutation Rate Depends on agr Locus Expression during Oxacillin-Mediated Heterogeneous-Homogeneous Selection in Methicillin-Resistant Staphylococcus aureus Clinical Strains by PLATA, Konrad B, ROSATO, Roberto R, ROSATO, Adriana E

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The histone deacetylase inhibitor LAQ824 induces human leukemia cell death through a process involving XIAP down-regulation, oxidative injury, and the acid sphingomyelinase-dependent generation of ceramide by Rosato, Roberto R, Maggio, Sonia C, Almenara, Jorge A, Payne, Shawn G, Atadja, Peter, Spiegel, Sarah, Dent, Paul, Grant, Steven

“…Determinants of differentiation and apoptosis induction by the novel histone deacetylase inhibitor (HDACI) LAQ824 were examined in human leukemia cells (U937…”
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