Search Results - "ROSA, Bruce A"

Temporal Dynamics of Growth and Photosynthesis Suppression in Response to Jasmonate Signaling by Attaran, Elham, Major, Ian T., Cruz, Jeffrey A., Rosa, Bruce A., Koo, Abraham J.K., Chen, Jin, Kramer, David M., He, Sheng Yang, Howe, Gregg A.

“…Biotic stress constrains plant productivity in natural and agricultural ecosystems. Repression of photosynthetic genes is a conserved plant response to biotic…”
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Intestinal cell diversity and treatment responses in a parasitic nematode at single cell resolution by Tyagi, Rahul, Rosa, Bruce A, Swain, Amanda, Artyomov, Maxim N, Jasmer, Douglas P, Mitreva, Makedonka

“…Parasitic nematodes, significant pathogens for humans, animals, and plants, depend on diverse organ systems for intra-host survival. Understanding the cellular…”
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Dynamic changes in human-gut microbiome in relation to a placebo-controlled anthelminthic trial in Indonesia by Martin, Ivonne, Djuardi, Yenny, Sartono, Erliyani, Rosa, Bruce A, Supali, Taniawati, Mitreva, Makedonka, Houwing-Duistermaat, Jeanine J, Yazdanbakhsh, Maria

“…Microbiome studies suggest the presence of an interaction between the human gut microbiome and soil-transmitted helminth. Upon deworming, a complex interaction…”
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Poly(ADP-ribose) polymerase 9 mediates early protection against Mycobacterium tuberculosis infection by regulating type I IFN production by Thirunavukkarasu, Shyamala, Ahmed, Mushtaq, Rosa, Bruce A, Boothby, Mark, Cho, Sung Hoon, Rangel-Moreno, Javier, Mbandi, Stanley K, Schreiber, Valérie, Gupta, Ananya, Zuniga, Joaquin, Mitreva, Makedonka, Kaushal, Deepak, Scriba, Thomas J, Khader, Shabaana A

“…The ADP ribosyltransferases (PARPs 1-17) regulate diverse cellular processes, including DNA damage repair. PARPs are classified on the basis of their ability…”
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Genomes of Fasciola hepatica from the Americas Reveal Colonization with Neorickettsia Endobacteria Related to the Agents of Potomac Horse and Human Sennetsu Fevers by McNulty, Samantha N, Tort, Jose F, Rinaldi, Gabriel, Fischer, Kerstin, Rosa, Bruce A, Smircich, Pablo, Fontenla, Santiago, Choi, Young-Jun, Tyagi, Rahul, Hallsworth-Pepin, Kymberlie, Mann, Victoria H, Kammili, Lakshmi, Latham, Patricia S, Dell'Oca, Nicolas, Dominguez, Fernanda, Carmona, Carlos, Fischer, Peter U, Brindley, Paul J, Mitreva, Makedonka

“…Food borne trematodes (FBTs) are an assemblage of platyhelminth parasites transmitted through the food chain, four of which are recognized as neglected…”
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Discovery of anthelmintic drug targets and drugs using chokepoints in nematode metabolic pathways by Taylor, Christina M, Wang, Qi, Rosa, Bruce A, Huang, Stanley Ching-Cheng, Powell, Kerrie, Schedl, Tim, Pearce, Edward J, Abubucker, Sahar, Mitreva, Makedonka

“…Parasitic roundworm infections plague more than 2 billion people (1/3 of humanity) and cause drastic losses in crops and livestock. New anthelmintic drugs are…”
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Genome of the human hookworm Necator americanus by Tang, Yat T, Gao, Xin, Rosa, Bruce A, Abubucker, Sahar, Hallsworth-Pepin, Kymberlie, Martin, John, Tyagi, Rahul, Heizer, Esley, Zhang, Xu, Bhonagiri-Palsikar, Veena, Minx, Patrick, Warren, Wesley C, Wang, Qi, Zhan, Bin, Hotez, Peter J, Sternberg, Paul W, Dougall, Annette, Gaze, Soraya Torres, Mulvenna, Jason, Sotillo, Javier, Ranganathan, Shoba, Rabelo, Elida M, Wilson, Richard K, Felgner, Philip L, Bethony, Jeffrey, Hawdon, John M, Gasser, Robin B, Loukas, Alex, Mitreva, Makedonka

“…Makedonka Mitreva and colleagues report the genome sequence and transcriptome analysis of the hookworm Necator americanus , a prevalent soil-transmitted human…”
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Differential human gut microbiome assemblages during soil-transmitted helminth infections in Indonesia and Liberia by Rosa, Bruce A, Supali, Taniawati, Gankpala, Lincoln, Djuardi, Yenny, Sartono, Erliyani, Zhou, Yanjiao, Fischer, Kerstin, Martin, John, Tyagi, Rahul, Bolay, Fatorma K, Fischer, Peter U, Yazdanbakhsh, Maria, Mitreva, Makedonka

“…The human intestine and its microbiota is the most common infection site for soil-transmitted helminths (STHs), which affect the well-being of ~ 1.5 billion…”
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Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia by Sheikh, Alaullah, Tumala, Brunda, Vickers, Tim J., Martin, John C., Rosa, Bruce A., Sabui, Subrata, Basu, Supratim, Simoes, Rita D., Mitreva, Makedonka, Storer, Chad, Tyksen, Erik, Head, Richard D., Beatty, Wandy, Said, Hamid M., Fleckenstein, James M.

“…Enterotoxigenic E. coli (ETEC) produce heat-labile (LT) and/or heat-stable (ST) enterotoxins, and commonly cause diarrhea in resource-poor regions. ETEC have…”
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Altered ratio of dendritic cell subsets in skin-draining lymph nodes promotes Th2-driven contact hypersensitivity by Miller, Hannah L., Andhey, Prabhakar Sairam, Swiecki, Melissa K., Rosa, Bruce A., Zaitsev, Konstantin, Villani, Alexandra-Chloe, Mitreva, Makedonka, Artyomov, Maxim N., Gilfillan, Susan, Cella, Marina, Colonna, Marco

“…Plasmacytoid dendritic cells (pDCs) specialize in the production of type I IFN (IFN-I). pDCs can be depleted in vivo by injecting diphtheria toxin (DT) in a…”
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Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis by Monin, Leticia, Griffiths, Kristin L, Lam, Wing Y, Gopal, Radha, Kang, Dongwan D, Ahmed, Mushtaq, Rajamanickam, Anuradha, Cruz-Lagunas, Alfredo, Zúñiga, Joaquín, Babu, Subash, Kolls, Jay K, Mitreva, Makedonka, Rosa, Bruce A, Ramos-Payan, Rosalio, Morrison, Thomas E, Murray, Peter J, Rangel-Moreno, Javier, Pearce, Edward J, Khader, Shabaana A

“…Parasitic helminth worms, such as Schistosoma mansoni, are endemic in regions with a high prevalence of tuberculosis (TB) among the population. Human studies…”
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Escherichia coli O157:H7 induces stronger plant immunity than Salmonella enterica Typhimurium SL1344 by Roy, Debanjana, Panchal, Shweta, Rosa, Bruce A, Melotto, Maeli

“…Consumption of fresh produce contaminated with bacterial human pathogens has resulted in various, sometimes deadly, disease outbreaks. In this study, we…”
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Social and psychological adversity are associated with distinct mother and infant gut microbiome variations by Warner, Barbara B., Rosa, Bruce A., Ndao, I. Malick, Tarr, Phillip I., Miller, J. Philip, England, Sarah K., Luby, Joan L., Rogers, Cynthia E., Hall-Moore, Carla, Bryant, Renay E., Wang, Jacqueline D., Linneman, Laura A., Smyser, Tara A., Smyser, Christopher D., Barch, Deanna M., Miller, Gregory E., Chen, Edith, Martin, John, Mitreva, Makedonka

“…Health disparities are driven by underlying social disadvantage and psychosocial stressors. However, how social disadvantage and psychosocial stressors lead to…”
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The proteome of extracellular vesicles of the lung fluke Paragonimus kellicotti produced in vitro and in the lung cyst by Di Maggio, Lucia S., Fischer, Kerstin, Yates, Devyn, Curtis, Kurt C., Rosa, Bruce A., Martin, John, Erdmann-Gilmore, Petra, Sprung, Robert S. W., Mitreva, Makedonka, Townsend, R. Reid, Weil, Gary J., Fischer, Peter U.

“…Paragonimiasis is a zoonotic, food-borne trematode infection that affects 21 million people globally. Trematodes interact with their hosts via extracellular…”
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The gut microbial metabolic capacity of microbiome-humanized vs. wild type rodents reveals a likely dual role of intestinal bacteria in hepato-intestinal schistosomiasis by Cortés, Alba, Martin, John, Rosa, Bruce A, Stark, Klara A, Clare, Simon, McCarthy, Catherine, Harcourt, Katherine, Brandt, Cordelia, Tolley, Charlotte, Lawley, Trevor D, Mitreva, Makedonka, Berriman, Matthew, Rinaldi, Gabriel, Cantacessi, Cinzia

“…Increasing evidence shows that the host gut microbiota might be involved in the immunological cascade that culminates with the formation of tissue granulomas…”
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Alteration of the fecal microbiota in Chinese patients with Schistosoma japonicum infection by Jiang, Yanyan, Yuan, Zhongying, Shen, Yujuan, Rosa, Bruce A, Martin, John, Cao, Shengkui, Zhou, Yanjiao, Mitreva, Makedonka, Cao, Jianping

“…Schistosoma japonicum infection causes pathological injury to the host. Multiple studies have shown that intestinal helminth infection causes dysbiosis for the…”
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Omics Driven Understanding of the Intestines of Parasitic Nematodes by Jasmer, Douglas P, Rosa, Bruce A, Tyagi, Rahul, Mitreva, Makedonka

“…The biological and molecular complexity of nematodes has impeded research on development of new therapies for treatment and control. We have focused on the…”
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Genome-wide tissue-specific gene expression, co-expression and regulation of co-expressed genes in adult nematode Ascaris suum by Rosa, Bruce A, Jasmer, Douglas P, Mitreva, Makedonka

“…Caenorhabditis elegans has traditionally been used as a model for studying nematode biology, but its small size limits the ability for researchers to perform…”
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IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection by Rosa, Bruce A., Ahmed, Mushtaq, Singh, Dhiraj K., Choreño-Parra, José Alberto, Cole, Journey, Jiménez-Álvarez, Luis Armando, Rodríguez-Reyna, Tatiana Sofía, Singh, Bindu, Gonzalez, Olga, Carrion, Ricardo, Schlesinger, Larry S., Martin, John, Zúñiga, Joaquín, Mitreva, Makedonka, Kaushal, Deepak, Khader, Shabaana A.

“…SARS-CoV-2 virus has infected more than 92 million people worldwide resulting in the Coronavirus disease 2019 (COVID-19). Using a rhesus macaque model of…”
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Cell Death and Transcriptional Responses Induced in Larvae of the Nematode Haemonchus contortus by Toxins/Toxicants with Broad Phylogenetic Efficacy by Jasmer, Douglas P, Rosa, Bruce A, Mitreva, Makedonka

“…Establishing methods to investigate treatments that induce cell death in parasitic nematodes will promote experimental approaches to elucidate mechanisms and…”
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