Search Results - "RORABAUGH, Boyd R"
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Does Prenatal Exposure to CNS Stimulants Increase the Risk of Cardiovascular Disease in Adult Offspring?
Published in Frontiers in cardiovascular medicine (04-03-2021)“…Prenatal exposure to an adverse uterine environment can have long lasting effects on adult offspring through DNA methylation, histone acetylation, and other…”
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2
Methamphetamine-induced changes in myocardial gene transcription are sex-dependent
Published in BMC genomics (12-04-2021)“…Prior work demonstrated that female rats (but not their male littermates) exposed to methamphetamine become hypersensitive to myocardial ischemic injury…”
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3
Maternal use of methamphetamine induces sex‐dependent changes in myocardial gene expression in adult offspring
Published in Physiological reports (01-11-2022)“…Methamphetamine is a commonly abused illicit stimulant that has prevalent use among women of child‐bearing age. While there are extensive studies on the…”
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4
Thymidine Phosphorylase Deficiency or Inhibition Preserves Cardiac Function in Mice With Acute Myocardial Infarction
Published in Journal of the American Heart Association (04-04-2023)“…Background Ischemic cardiovascular disease is the leading cause of death worldwide. Current pharmacologic therapy has multiple limitations, and patients remain…”
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5
Repeated exposure to methamphetamine induces sex-dependent hypersensitivity to ischemic injury in the adult rat heart
Published in PloS one (02-06-2017)“…We previously reported that adult female, but not male rats that were prenatally exposed to methamphetamine exhibit myocardial hypersensitivity to ischemic…”
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6
Glucocorticoid Abnormalities in Female Rats Exposed to a Predator-Based Psychosocial Stress Model of PTSD
Published in Frontiers in behavioral neuroscience (18-06-2021)“…People with post-traumatic stress disorder (PTSD) exhibit heightened anxiety and enhanced negative feedback of the hypothalamus-pituitary-adrenal (HPA) axis…”
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Prenatal Exposure to Methamphetamine Causes Vascular Dysfunction in Adult Male Rat Offspring
Published in Frontiers in cardiovascular medicine (26-01-2022)“…Methamphetamine use during pregnancy can have negative consequences on the offspring. However, most studies investigating the impact of prenatal exposure to…”
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Acute Stress Decreases but Chronic Stress Increases Myocardial Sensitivity to Ischemic Injury in Rodents
Published in Frontiers in psychiatry (25-04-2016)“…Cardiovascular disease (CVD) is the largest cause of mortality worldwide, and stress is a significant contributor to the development of CVD. The relationship…”
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9
Pre-Learning Stress That Is Temporally Removed from Acquisition Impairs Fear Learning
Published in Biology (Basel, Switzerland) (26-05-2023)“…Few studies have examined the time-dependent effects of stress on fear learning. Previously, we found that stress immediately before fear conditioning enhanced…”
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10
α1A - and α1B -adrenergic receptors differentially modulate antidepressant-like behavior in the mouse
Published in Brain research (18-08-2009)“…Abstract Tricyclic antidepressant (TCA) drugs are used for the treatment of chronic depression, obsessive–compulsive disorder (OCD), and anxiety-related…”
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11
Maternal use of methamphetamine alters cardiovascular function in the adult offspring
Published in Biochemistry and cell biology (01-05-2023)“…Methamphetamine is one of the most commonly used illicit drugs during pregnancy. Most studies investigating the impact of maternal use of methamphetamine on…”
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Chronic Administration of Cannabinoid Agonists ACEA, AM1241, and CP55,940 Induce Sex-Specific Differences in Tolerance and Sex Hormone Changes in a Chemotherapy-Induced Peripheral Neuropathy
Published in The Journal of pharmacology and experimental therapeutics (18-10-2024)“…Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of chemotherapy treatment, routinely manifesting as increased pain sensitivity…”
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13
Sex‐Dependent Changes in Vascular Function in Adult Rats Following Prenatal Exposure to Methamphetamine
Published in The FASEB journal (01-05-2022)“…Background Prenatal exposure to central nervous system stimulants such as cocaine, nicotine, and caffeine alters cardiovascular function in adult offspring…”
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14
Methamphetamine use during the first or second half of pregnancy worsens cardiac ischemic injury in adult female offspring
Published in Physiological research (01-08-2022)“…There is growing evidence that methamphetamine use during pregnancy may produce detrimental cardiovascular effects in the adult offspring. Prior work…”
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Regulator of G protein signaling 2 differentially regulates nicotine‐induced anxiolytic‐ and antidepressant‐like effects in mice
Published in The European journal of neuroscience (01-09-2018)“…This study assessed the role of regulator of G protein signaling 2 (RGS2) in nicotine‐induced anxiolytic‐ and antidepressant‐like effects using RGS2 wildtype…”
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Social evaluative stress enhances central detail memory, reduces false memory, and results in intrusive memories that last for days
Published in Neurobiology of learning and memory (01-03-2024)“…Few studies have quantified what an individual remembers about a laboratory-controlled stressor. Here, we aimed to replicate previous work by using a modified…”
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Regulators of G-protein signaling 2 and 4 differentially regulate cocaine-induced rewarding effects
Published in Physiology & behavior (15-10-2018)“…There is a need to identify new therapeutic targets for the treatment of cocaine addiction due to the rise in cocaine abuse and deaths due to cocaine overdose…”
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Attenuation of nicotine-induced rewarding and antidepressant-like effects in male and female mice lacking regulator of G-protein signaling 2
Published in Pharmacology, biochemistry and behavior (01-02-2022)“…Nicotine-induced rewarding and mood altering effects contribute to the continued use of nicotine and the subsequent development of nicotine dependence. The…”
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Prenatal methamphetamine differentially alters myocardial sensitivity to ischemic injury in male and female adult hearts
Published in American journal of physiology. Heart and circulatory physiology (15-02-2016)“…Methamphetamine is one of the most common illicit drugs abused during pregnancy. The neurological effects of prenatal methamphetamine are well known. However,…”
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20
A predator-based psychosocial stress animal model of PTSD in females: Influence of estrous phase and ovarian hormones
Published in Hormones and behavior (01-09-2019)“…Traumatized women are more likely than traumatized men to develop post-traumatic stress disorder (PTSD). Still, the inclusion of females in animal models of…”
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