Search Results - "ROQUES, B"

Comparison of toxicokinetic properties of eleven analogues of Bisphenol A in pig after intravenous and oral administrations by Gély, Clémence A., Lacroix, Marlène Z., Roques, Béatrice B., Toutain, Pierre-Louis, Gayrard, Véronique, Picard-Hagen, Nicole

“…[Display omitted] •The mixture approach used in this toxicokinetic study allows reducing animal testing.•Bisphenol S results in the highest systemic exposure…”
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Delivery strategies to improve piglets exposure to oral antimicrobials by Hernández, Noslen, Roques, Béatrice B, Lacroix, Marlène Z, Concordet, Didier

“…The widespread practice of delivering antimicrobials through drinking water to livestock leads to considerable variability in exposure levels among animals,…”
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Can oral group medication be improved to reduce antimicrobial use? by Ferran, Aude A., Roques, Béatrice B.

“…email: a.ferran@envt.fr Of the antimicrobials sold to treat food-producing animals in Europe in 2016, 90.1 per cent were designated for group treatment.1 Group…”
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Pharmacokinetic–pharmacodynamic cutoff values for benzylpenicillin in horses to support the establishment of clinical breakpoints for benzylpenicillin antimicrobial susceptibility testing in horses by Lallemand, Elodie A., Bousquet-Mélou, Alain, Chapuis, Laura, Davis, Jennifer, Ferran, Aude A., Kukanich, Butch, Kuroda, Taisuke, Lacroix, Marlène Z., Minamijima, Yohei, Olsén, Lena, Pelligand, Ludovic, Portugal, Felipe Ramon, Roques, Béatrice B., Santschi, Elizabeth M., Wilson, Katherine E., Toutain, Pierre-Louis

“…IntroductionThe aim of this international project was to establish a species-specific Clinical Breakpoint for interpretation of Antimicrobial Susceptibility…”
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The sub-MIC selective window decreases along the digestive tract: determination of the minimal selective concentration of oxytetracycline in sterilised intestinal contents by Imazaki, Pedro Henrique, Voisin, Bertille, Arpaillange, Nathalie, Roques, Béatrice B., Dordet-Frisoni, Emilie, Dupouy, Véronique, Ferran, Aude A., Bousquet-Mélou, Alain, Bibbal, Delphine

“…The administration of antibiotics can expose the digestive microbiota of humans and animals to sub-inhibitory concentrations, potentially favouring the…”
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Short course of immune-suppressive doses of prednisolone, evaluated through a prospective double-masked placebo-controlled clinical trial in healthy Beagles, is associated with sustained modifications in renal, hydration, and electrolytic status by Mantelli, M I, Roques, B B, Blanchard, T A, Mounier, M, Quincey, M, Jolivet, F B, Jousserand, N P, Marchand, A, Diquélou, A N, Reynolds, B S, Coyne, M, Trumel, C, Lefebvre, H P, Concordet, D, Lavoué, R

“…To investigate the effects and duration of orally administered prednisolone on renal function evaluated by glomerular filtration rate (GFR) determination and…”
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Prediction of Minocycline Activity in the Gut From a Pig Preclinical Model Using a Pharmacokinetic -Pharmacodynamic Approach by Vallé, Quentin, Roques, Béatrice B., Bousquet-Mélou, Alain, Dahlhaus, David, Ramon-Portugal, Felipe, Dupouy, Véronique, Bibbal, Delphine, Ferran, Aude A.

“…The increase of multidrug-resistant (MDR) bacteria has renewed interest in old antibiotics, such as minocycline, that can be active against various MDR…”
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The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism by Roques, Béatrice B., Leghait, Julien, Lacroix, Marlène Z., Lasserre, Frédéric, Pineau, Thierry, Viguié, Catherine, Martin, Pascal G.P.

“…Fipronil is described as a thyroid disruptor in rat. Based on the hypothesis that this results from a perturbation of hepatic thyroid hormone metabolism, our…”
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NMR Structure of the HIV-1 Regulatory Protein VPR by Morellet, N, Bouaziz, S, Petitjean, P, Roques, B.P

“…The human immunodeficiency virus type 1 (HIV-1) genome encodes a highly conserved regulatory gene product, Vpr (96 residues, 14 kDa), which is incorporated…”
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Levers to Improve Antibiotic Treatment of Lambs via Drinking Water in Sheep Fattening Houses: The Example of the Sulfadimethoxine/Trimethoprim Combination by Ferran, Aude A., Lacroix, Marlène Z., Bousquet-Mélou, Alain, Duhil, Ivain, Roques, Béatrice B.

“…To limit the spread of bacterial diseases in sheep fattening houses, antibiotics are often administered collectively. Collective treatments can be delivered by…”
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Predicted efficacy and tolerance of different dosage regimens of benzylpenicillin in horses based on a pharmacokinetic study with three IM formulations and one IV formulation by Ferran, Aude A, Roques, Béatrice B, Chapuis, Laura, Kuroda, Taisuke, Lacroix, Marlène Z, Toutain, Pierre-Louis, Bousquet-Melou, Alain, Lallemand, Elodie A

“…Benzylpenicillin (BP) is a first-line antibiotic in horses but there are discrepancies between manufacturers and literature recommendations regarding dosing…”
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Doxycycline serum protein binding in pigs reveals a relatively high free fraction by Portugal, Felipe Ramon, Lacroix, Marlène Z., Roques, Béatrice B., Gayrard, Véronique, Toutain, Pierre‐Louis, Bousquet‐Mélou, Alain

“…Doxycycline is an antibiotic widely used in pig farming. As with all antibiotics, only the free concentrations are considered to be bacteriologically active…”
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Transcriptomic modifications of the thyroid gland upon exposure to phytosanitary-grade fipronil: Evidence for the activation of compensatory pathways by Martin, Pascal G.P., Dupouy, Véronique, Leghait, Julien, Pineau, Thierry, Polizzi, Arnaud, Lasserre, Frédéric, Roques, Béatrice B., Viguié, Catherine

“…Fipronil is a phenylpyrazole insecticide used for the control of a variety of pest for domestic, veterinary and agricultural uses. Fipronil exposure is…”
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Maternal and Fetal Exposure to Bisphenol A Is Associated with Alterations of Thyroid Function in Pregnant Ewes and Their Newborn Lambs by Viguié, Catherine, Collet, Séverine H, Gayrard, Véronique, Picard-Hagen, Nicole, Puel, Sylvie, Roques, Béatrice B, Toutain, Pierre-Louis, Lacroix, Marlène Z

“…The putative thyroid-disrupting properties of bisphenol A (BPA) highlight the need for an evaluation of fetal exposure and its consequence on the…”
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Kinetic disposition of diazepam and its metabolites after intravenous administration of diazepam in the horse: Relevance for doping control by Schenk, Ina, Machnik, Marc, Broussou, Diane, Meuly, Astrid, Roques, Béatrice B., Lallemand, Elodie, Düe, Michael, Röttgen, Helma, Lagershausen, Henrike, Toutain, Pierre‐Louis, Thevis, Mario

“…In horses, the benzodiazepine diazepam (DIA) is used as sedative for pre‐medication or as an anxiolytic to facilitate horse examinations. As the sedative…”
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CYP450-dependent biotransformation of the insecticide fipronil into fipronil sulfone can mediate fipronil-induced thyroid disruption in rats by Roques, Béatrice B, Lacroix, Marlène Z, Puel, Sylvie, Gayrard, Véronique, Picard-Hagen, Nicole, Jouanin, Isabelle, Perdu, Elisabeth, Martin, Pascal G, Viguié, Catherine

“…In rats, the widely used insecticide fipronil increases the clearance of thyroxine (T(4)). This effect is associated with a high plasma concentration of…”
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Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the µ-opioid-receptor gene by Matthes, Hans W. D, Maldonado, Rafael, Simonin, Frédéric, Valverde, Olga, Slowe, Susan, Kitchen, Ian, Befort, Katia, Dierich, Andrée, Le Meur, Marianne, Dollé, Pascal, Tzavara, Eleni, Hanoune, Jacques, Roques, Bernard P, Kieffer, Brigitte L

“…Despite tremendous efforts in the search for safe, efficacious and non-addictive opioids for pain treatment, morphine remains the most valuable painkiller in…”
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Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice by LEDENT, C, VALVERDE, O, VASSART, G, FRATTA, W, PARMENTIER, M, COSSU, G, PETITET, F, AUBERT, J.-F, BESLOT, F, BÖHME, G. A, IMPERATO, A, PEDRAZZINI, T, ROQUES, B. P

“…The function of the central cannabinoid receptor (CB1) was investigated by invalidating its gene. Mutant mice did not respond to cannabinoid drugs,…”
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Physiological control of emotion-related behaviors by endogenous enkephalins involves essentially the delta opioid receptors by Nieto, M. Mas, Guen, S.L.E., Kieffer, B.L., Roques, B.P., Noble, F.

“…The endogenous pentapeptide enkephalins bind to the mu and delta opioid receptors, with a slightly higher affinity for the latter. It remains a controversy…”
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Population Pharmacokinetics of Intravenous Amoxicillin Combined With Clavulanic Acid in Healthy and Critically Ill Dogs by Vegas Cómitre, Maria D., Cortellini, Stefano, Cherlet, Marc, Devreese, Mathias, Roques, Beatrice B., Bousquet-Melou, Alain, Toutain, Pierre-Louis, Pelligand, Ludovic

“…Background: Data regarding antimicrobial pharmacokinetics (PK) in critically ill dogs are lacking and likely differ from those of healthy dogs. The aim of this…”
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