Search Results - "ROOS, Anja"

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population by Gaya da Costa, Mariana, Poppelaars, Felix, van Kooten, Cees, Mollnes, Tom E, Tedesco, Francesco, Würzner, Reinhard, Trouw, Leendert A, Truedsson, Lennart, Daha, Mohamed R, Roos, Anja, Seelen, Marc A

“…The complement system is essential for an adequate immune response. Much attention has been given to the role of complement in disease. However, to better…”
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High-Resolution Melting Analysis (HRMA)--More than just sequence variant screening by Vossen, Rolf H.A.M, Aten, Emmelien, Roos, Anja, den Dunnen, Johan T

“…Transition of the double-stranded DNA molecule to its two single strands, DNA denaturation or melting, has been used for many years to study DNA structure and…”
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IL-10–producing macrophages preferentially clear early apoptotic cells by Xu, Wei, Roos, Anja, Schlagwein, Nicole, Woltman, Andrea M., Daha, Mohamed R., van Kooten, Cees

“…Efficient clearance of apoptotic cells seems to be a prerequisite to prevent the development of autoimmunity. Here we identify that macrophage…”
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Secretory IgA N- and O-Glycans Provide a Link between the Innate and Adaptive Immune Systems by Royle, Louise, Roos, Anja, Harvey, David J., Wormald, Mark R., Van Gijlswijk-Janssen, Daniëlle, Redwan, El-Rashdy M., Wilson, Ian A., Daha, Mohamed R., Dwek, Raymond A., Rudd, Pauline M.

“…Secretory IgA (SIgA) is a multi-polypeptide complex consisting of a secretory component (SC) covalently attached to dimeric IgA containing one joining (J)…”
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Biochemical and functional characterization of the interaction between pentraxin 3 and C1q by Nauta, Alma J., Bottazzi, Barbara, Mantovani, Alberto, Salvatori, Giovanni, Kishore, Uday, Schwaeble, Wilhelm J., Gingras, Alexandre R., Tzima, Sotiria, Vivanco, Fernando, Egido, Jesús, Tijsma, Odette, Hack, Erik C., Daha, Mohamed R., Roos, Anja

“…Pentraxin 3 (PTX3) is a recently characterized member of the pentraxin family of acute‐phase proteins produced during inflammation. Classical short pentraxins,…”
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Mini‐review: A pivotal role for innate immunity in the clearance of apoptotic cells by Roos, Anja, Xu, Wei, Castellano, Giuseppe, Nauta, Alma J., Garred, Peter, Daha, Mohamed R., van Kooten, Cees

“…Apoptotic cells can be recognized and taken up by both macrophages and dendritic cells. Phagocytosis of apoptotic cells generally leads to active suppression…”
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Recognition and clearance of apoptotic cells: a role for complement and pentraxins by Nauta, Alma J, Daha, Mohamed R, Kooten, Cees van, Roos, Anja

“…Apoptotic cells are specifically recognized and rapidly removed by professional phagocytes or neighboring cells by incompletely characterized mechanisms…”
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Lectin complement pathway gene profile of donor and recipient determine the risk of bacterial infections after orthotopic liver transplantation by de Rooij, Bert‐Jan F., van Hoek, Bart, ten Hove, W. Rogier, Roos, Anja, Bouwman, Lee H., Schaapherder, Alexander F., Porte, Robert J., Daha, Mohamed R., van der Reijden, Johan J., Coenraad, Minneke J., Ringers, Jan, Baranski, Andrzej G., Hepkema, Bouke G., Hommes, Daniel W., Verspaget, Hein W.

“…Infectious complications after orthotopic liver transplantation (OLT) are a major clinical problem. The lectin pathway of complement activation is…”
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Human peritoneal macrophages show functional characteristics of M‐CSF‐driven anti‐inflammatory type 2 macrophages by Xu, Wei, Schlagwein, Nicole, Roos, Anja, van den Berg, Timo K., Daha, Mohamed R., van Kooten, Cees

“…We have recently shown that in vitro polarized M‐CSF‐driven anti‐inflammatory macrophages (MΦ2) have the unique capacity to preferentially bind and ingest…”
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Human IgA Activates the Complement System Via the Mannan-Binding Lectin Pathway by Roos, Anja, Bouwman, Lee H, van Gijlswijk-Janssen, Danielle J, Faber-Krol, Maria C, Stahl, Gregory L, Daha, Mohamed R

“…The recently identified lectin pathway of the complement system, initiated by binding of mannan-binding lectin (MBL) to its ligands, is a key component of…”
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Direct binding of C1q to apoptotic cells and cell blebs induces complement activation by Nauta, Alma J., Trouw, Leendert A., Daha, Mohamed R., Tijsma, Odette, Nieuwland, Rienk, Schwaeble, Wilhelm J., Gingras, Alexandre R., Mantovani, Alberto, Hack, Erik C., Roos, Anja

“…Deficiency of early components of the classical pathway of complement, particularly C1q, predisposes to the development of systemic lupus erythematosus…”
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Mannose-binding lectin and Ficolin-2 gene polymorphisms predispose to cytomegalovirus (re)infection after orthotopic liver transplantation by de Rooij, Bert-Jan F, van der Beek, Martha T, van Hoek, Bart, Vossen, Ann C.T.M, Rogier ten Hove, W, Roos, Anja, Schaapherder, Alexander F, Porte, Robert J, van der Reijden, Johan J, Coenraad, Minneke J, Hommes, Daniel W, Verspaget, Hein W

“…Background & Aims The lectin pathway of complement activation is a crucial effector cascade of the innate immune response to pathogens. Cytomegalovirus (CMV)…”
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Maturation of dendritic cells abrogates C1q production in vivo and in vitro by Castellano, Giuseppe, Woltman, Andrea M., Nauta, Alma J., Roos, Anja, Trouw, Leendert A., Seelen, Marc A., Schena, Francesco Paolo, Daha, Mohamed R., van Kooten, Cees

“…Dendritic cells (DCs) and complement are essential components of the innate immune system. Immature DCs (immDCs) and mature DCs (mDCs) can migrate to lymphoid…”
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Human renal epithelial cells produce the long pentraxin PTX3 by Nauta, Alma J., De Haij, Simone, Bottazzi, Barbara, Mantovani, Alberto, Borrias, Maria C., Aten, Jan, Rastaldi, Maria Pia, Daha, Mohamed R., Van Kooten, Cees, Roos, Anja

“…Human renal epithelial cells produce the long pentraxin PTX3. Pentraxin 3 (PTX3) is a prototypic long pentraxin with structural similarities in the C-terminal…”
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The Role of Secretory IgA and Complement in IgA Nephropathy by Oortwijn, Beatrijs D., PhD, Eijgenraam, Jan-Willem, MD, Rastaldi, Maria-Pia, MD, PhD, Roos, Anja, PhD, Daha, Mohamed R., PhD, van Kooten, Cees, PhD

“…Summary IgA nephropathy (IgAN) is characterized by glomerular deposition of IgA, often together with complement components. This deposited IgA is mainly…”
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A novel method to standardise serum IgA measurements shows an increased prevalence of IgA deficiency in young children with recurrent respiratory tract infections by Koenen, Mischa H, Bosma, Madeleen, Roorda, Udo A, Wopereis, Fabiënne MY, Roos, Anja, der Vries, Erhard, Bogaert, Debby, Sanders, Elisabeth AM, Boes, Marianne, Heidema, Jojanneke, Montfrans, Joris M, Balemans, Walter AF, Holten, Thijs C, Verhagen, Lilly M

“…Objectives While physicians are often confronted with immunoglobulin A (IgA) deficiency in children with recurrent infections, the clinical relevance of this…”
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The membrane attack complex of complement induces caspase activation and apoptosis by Nauta, Alma J., Daha, Mohamed R., Tijsma, Odette, van de Water, Bob, Tedesco, Francesco, Roos, Anja

“…Activation of the terminal pathway of the complement system leads to insertion of terminal complement complexes (C5b‐9) into the cell membrane, which may…”
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Mannose-Binding Lectin Contributes to the Severity of Guillain-Barre Syndrome by Geleijns, Karin, Roos, Anja, Houwing-Duistermaat, Jeanine J, van Rijs, Wouter, Tio-Gillen, Anne P, Laman, Jon D, van Doorn, Pieter A, Jacobs, Bart C

“…In Guillain-Barré syndrome (GBS), complement activation plays a crucial role in the induction and extent of the postinfectious immune-mediated peripheral nerve…”
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High-throughput genotyping of mannose-binding lectin variants using high-resolution DNA-melting analysis by Vossen, Rolf H.A.M., van Duijn, Martine, Daha, Mohamed R., den Dunnen, Johan T., Roos, Anja

“…High Resolution Melting Analysis (HRMA) is a rapid and sensitive method for single nucleotide polymorphism (SNP) analysis. In the present study we present a…”
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Proinflammatory changes in human umbilical cord vein endothelial cells can be induced neither by native nor by modified CRP by Oroszlán, Melinda, Herczenik, Eszter, Rugonfalvi-Kiss, Szabolcs, Roos, Anja, Nauta, Alma J, Daha, Mohamed R, Gombos, Imre, Karádi, István, Romics, László, Prohászka, Zoltán, Füst, George, Cervenak, László

“…The role of C-reactive protein (CRP) in atherosclerosis is controversial. It is not clear, either, if the presumed endothelium-activating effect of CRP resides…”
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