Search Results - "ROONEY, James F"
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Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study
Published in The Lancet infectious diseases (01-09-2014)“…Summary Background The effect of HIV pre-exposure prophylaxis (PrEP) depends on uptake, adherence, and sexual practices. We aimed to assess these factors in a…”
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2
Penetration of tenofovir and emtricitabine in mucosal tissues: implications for prevention of HIV-1 transmission
Published in Science translational medicine (07-12-2011)“…A mainstay of strategies to prevent HIV-1 transmission is to use antiretroviral therapy (ART) for pre-exposure prophylaxis (PrEP). Critical to the design and…”
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3
Timing of Antiretroviral Therapy for HIV-1 Infection and Tuberculosis
Published in The New England journal of medicine (20-10-2011)“…In this international study involving 809 patients with HIV and TB coinfection, earlier therapy for both infections, versus waiting 8 to 12 weeks to initiate…”
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4
Abacavir/Lamivudine Versus Tenofovir DF/Emtricitabine as Part of Combination Regimens for Initial Treatment of HIV: Final Results
Published in The Journal of infectious diseases (15-10-2011)“…Background. AIDS Clinical Trials Group A5202 compared blinded abacavir/lamivudine (ABC/3TC) to tenofovir DF/emtricitabine (TDF/FTC) with efavirenz (EFV) or…”
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5
Safety and adherence to intermittent pre-exposure prophylaxis (PrEP) for HIV-1 in African men who have sex with men and female sex workers
Published in PloS one (12-04-2012)“…Little is known about safety of and adherence to intermittent HIV PrEP regimens, which may be more feasible than daily dosing in some settings. We present…”
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6
In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide
Published in PloS one (19-02-2010)“…Tenofovir gel has entered into clinical trials for use as a topical microbicide to prevent HIV-1 infection but has no published data regarding pre-clinical…”
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7
Metabolic outcomes in a randomized trial of nucleoside, nonnucleoside and protease inhibitor-sparing regimens for initial HIV treatment
Published in AIDS (London) (01-06-2009)“…The metabolic effects of initial therapy for HIV-1 infection are important determinants of regimen selection. Open-label study in 753 subjects randomized…”
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8
Risk of tuberculosis after initiation of antiretroviral therapy among persons with HIV in Europe
Published in International journal of infectious diseases (01-10-2024)“…•The tuberculosis (TB) risk after antiretroviral treatment (ART) initiation in Europe is studied.•TB peaked within 3 months post ART (14.41/1000 PY).•TB was…”
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9
The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults : the first 4 years
Published in AIDS (London) (19-06-2007)“…To characterize the safety profile of tenofovir disoproxil fumarate (DF) for the treatment of HIV infection in adults over the first 4 years of use. A…”
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Safety, adherence and acceptability of intermittent tenofovir/emtricitabine as HIV pre-exposure prophylaxis (PrEP) among HIV-uninfected Ugandan volunteers living in HIV-serodiscordant relationships: a randomized, clinical trial
Published in PloS one (26-09-2013)“…Efficacy of oral pre-exposure prophylaxis (PrEP) in prevention of HIV acquisition has been evaluated using a daily regimen. However, adherence to long term…”
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11
A pilot study to determine the impact on dyslipidemia of adding tenofovir to stable background antiretroviral therapy: ACTG 5206
Published in AIDS (London) (17-07-2010)“…Several studies have reported improvement in lipids after antiretroviral therapy switches to tenofovir disoproxil fumarate (TDF)-containing regimens. We…”
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12
Safety and Pharmacokinetics of a Tenofovir Alafenamide Fumarate-Emtricitabine based Oral Antiretroviral Regimen for Prevention of HIV Acquisition in Women: A Randomized Controlled Trial
Published in EClinicalMedicine (01-06-2021)“…Daily oral emtricitabine (FTC, F)/tenofovir disoproxil fumarate (TDF) combination is approved for HIV pre-exposure prophylaxis (PrEP) in men and women…”
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13
In-utero exposure to tenofovir disoproxil fumarate pre-exposure prophylaxis and growth metrics in HIV unexposed breastfed infants in South Africa: a post hoc analysis of the CAP 016 PrEP in pregnancy RCT
Published in Frontiers in pediatrics (09-08-2024)“…We evaluated growth metrics in HIV unexposed African breastfed infants in the first 18 months of life in association with exposure to Tenofovir Diphosphate…”
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14
Evaluation of Xpert point-of-care assays for detection of HIV infection in persons using long-acting cabotegravir for pre-exposure prophylaxis
Published in Microbiology spectrum (09-07-2024)“…Detection of HIV infection may be challenging in persons using long-acting cabotegravir (CAB-LA) pre-exposure prophylaxis (PrEP) due to viral suppression and…”
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15
Natural Substrate Concentrations Can Modulate the Prophylactic Efficacy of Nucleotide HIV Reverse Transcriptase Inhibitors
Published in Journal of Virology (01-07-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Pharmacokinetics and Safety of Single-Dose Tenofovir Disoproxil Fumarate and Emtricitabine in HIV-1-Infected Pregnant Women and Their Infants
Published in Antimicrobial Agents and Chemotherapy (01-12-2011)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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17
Viral load Reduction in SHIV-Positive Nonhuman Primates via Long-Acting Subcutaneous Tenofovir Alafenamide Fumarate Release from a Nanofluidic Implant
Published in Pharmaceutics (17-10-2020)“…HIV-1 is a chronic disease managed by strictly adhering to daily antiretroviral therapy (ART). However, not all people living with HIV-1 have access to ART,…”
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18
An HIV Preexposure Prophylaxis Demonstration Project and Safety Study for Young MSM
Published in Journal of acquired immune deficiency syndromes (1999) (01-01-2017)“…BACKGROUND:Young men who have sex with men (YMSM) are a key population for implementation of preexposure prophylaxis (PrEP) interventions. This open-label…”
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On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection
Published in The New England journal of medicine (03-12-2015)“…In this trial of preexposure prophylaxis with tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) in men who have sex with men, TDF-FTC was found to be…”
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20
Characterization of Human Immunodeficiency Virus (HIV) Infection in Cisgender Men and Transgender Women Who Have Sex With Men Receiving Injectable Cabotegravir for HIV Prevention: HPTN 083
Published in The Journal of infectious diseases (16-11-2021)“…Abstract Background The HIV Prevention Trials Network (HPTN) 083 trial demonstrated that long-acting cabotegravir (CAB-LA) was more effective than tenofovir…”
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