Search Results - "ROOK, G. A. W."

99th Dahlem Conference on Infection, Inflammation and Chronic Inflammatory Disorders: Darwinian medicine and the 'hygiene' or 'old friends' hypothesis by Rook, G.A.W

“…The current synthesis of the 'hygiene hypothesis' suggests that the recent increase in chronic inflammatory disorders is at least partly attributable to…”
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Type 2 Cytokine Gene Activation and Its Relationship to Extent of Disease in Patients with Tuberculosis by Seah, G. T., Scott, G. M., Rook, G. A. W.

“…The extent of type 2 cytokine gene expression in patients with pulmonary tuberculosis (TB) was studied by use of quantitative nested reverse-transcription…”
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Identification of an immune-responsive mesolimbocortical serotonergic system: Potential role in regulation of emotional behavior by Lowry, C.A, Hollis, J.H, de Vries, A, Pan, B, Brunet, L.R, Hunt, J.R.F, Paton, J.F.R, van Kampen, E, Knight, D.M, Evans, A.K, Rook, G.A.W, Lightman, S.L

“…Abstract Peripheral immune activation can have profound physiological and behavioral effects including induction of fever and sickness behavior. One mechanism…”
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Mycobacteria and other environmental organisms as immunomodulators for immunoregulatory disorders by Rook, G A W, Adams, V, Hunt, J, Palmer, R, Martinelli, R, Brunet, L Rosa

“…In the rich, developed parts of the world there has been a steady and simultaneous increase in at least three groups of disease: (1) allergies, (2)…”
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Microbial ‘old friends’, immunoregulation and socioeconomic status by Rook, G. A. W., Raison, C. L., Lowry, C. A.

“…Summary The immune system evolved to require input from at least three sources that we collectively term the ‘old friends’: (i) the commensal microbiotas…”
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Intragastric administration of Mycobacterium vaccae inhibits severe pulmonary allergic inflammation in a mouse model by Hunt, J. R. F., Martinelli, R., Adams, V. C., Rook, G. A. W., Brunet, L. Rosa

“…Summary Background Coexistence with harmless microorganisms such as lactobacilli, saprophytic mycobacteria and some helminths, throughout evolution, may have…”
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Old friends for breakfast by Rook, G. A. W., Brunet, L. Rosa

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Microbes, immunoregulation, and the gut by Rook, G A W, Brunet, L R

“…Two distinct, but rapidly converging, areas of research (the hygiene hypothesis and the study of probiotic/prebiotic effects) have emphasised the need to…”
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Immunological and pathological comparative analysis between experimental latent tuberculous infection and progressive pulmonary tuberculosis by ARRIAGA, A. K., OROZCO, E. H., AGUILAR, L. D., ROOK, G. A. W., PANDO, R. HERNÁNDEZ

“…SUMMARY Mycobacterium tuberculosis produces latent infection or progressive disease. Indeed, latent infection is more common since it occurs in one‐third of…”
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Killed Mycobacterium vaccae suspension in children with moderate-to-severe atopic dermatitis: a randomized, double-blind, placebo-controlled trial by Berth-Jones, J., Arkwright, P. D., Marasovic, D., Savani, N., Aldridge, C. R., Leech, S. N., Morgan, C., Clark, S. M., Ogilvie, S., Chopra, S., Harper, J. I., Smith, C. H., Rook, G. A. W., Friedmann, P.S.

“…Summary Background The hygiene hypothesis is often proposed to explain the high prevalence of atopy in the western world. Dysregulation of the immune system…”
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The Microbiome of the Built Environment and Human Behavior: Implications for Emotional Health and Well-Being in Postmodern Western Societies by Stamper, C E, Hoisington, A J, Gomez, O M, Halweg-Edwards, A L, Smith, D G, Bates, K L, Kinney, K A, Postolache, T T, Brenner, L A, Rook, G A W, Lowry, C A

“…It is increasingly evident that inflammation is an important determinant of cognitive function and emotional behaviors that are dysregulated in stress-related…”
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Gene expression of IL17 and IL23 in the lungs of patients with active tuberculosis by Dheda, K, Chang, J-S, Lala, S, Huggett, J F, Zumla, A, Rook, G A W

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Maintained pregnancy levels of oestrogen afford complete protection from post‐partum exacerbation of collagen‐induced arthritis by MATTSSON, R., MATTSSON, A., HOLMDAHL, R., WHYTE, A., ROOK, G. A. W.

“…SUMMARY Pregnancy is known to influence the course of rheumatoid arthritis (RA) in women, as well as type II collagen‐induced arthritis (CIA) in DBA/1 mice. A…”
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The effects of Mycobacterium vaccae on allergen-induced airway responses in atopic asthma by Camporota, L, Corkhill, A, Long, H, Lordan, J, Stanciu, L, Tuckwell, N, Cross, A, Stanford, J.L, Rook, G.A.W, Holgate, S.T, Djukanovic, R

“…T-helper (Th)2 cytokines play a central role in asthma. Therefore, a double-blind randomised study was conducted to investigate whether heat-killed…”
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Agalactosyl IgG is elevated in patients with active spondyloarthropathy by LEIRISALO-REPO, M, HERNANDEZ-MUNOZ, H. E, ROOK, G. A. W

“…Patients with rheumatoid arthritis or with Crohn's disease have deficient galactosylation of serum IgG [Gal(0)]. To study whether such deviation occurs in…”
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THE PATHOGENESIS OF TUBERCULOSIS by Rook, G.A.W, Hernandez-Pando, Rogelio

“…Tuberculosis patients relapse if treatment is not continued for 6 months, because chemotherapy fails to convert the patients' response from the necrotizing…”
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Rheumatoid arthritis: how well do the theories fit the evidence? by McCULLOCH, J., LYDYARD, P. M., ROOK, G. A. W.

“…SUMMARY In this brief review, inspired partly by a symposium at the autumn meeting of the British Society for Immunology, 1992, varying hypotheses concerning…”
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An inhibitor of the toxicity of tumour necrosis factor in the serum of patients with sarcoidosis, tuberculosis and Crohn's disease by FOLEY, N., LAMBERT, C., McNICOL, M., JOHNSON, N., ROOK, G. A. W.

“…SUMMARY The activated macrophages present in the T cell‐dependent granulomata of sarcoidosis and tuberculosis are primed for enhanced release of cytokines…”
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Agalactosyl IgG in pristane‐induced arthritis. Pregnancy affects the incidence and severity of arthritis and the glycosylation status of IgG by THOMPSON, S. J., HITSUMOTO, Y., ZHANG, Y. W., ROOK, G. A. W., ELSON, C. J.

“…SUMMARY The effect of pregnancy on the incidence and severity of pristane‐induced arthritis was examined along with the glycosylation status of IgG during the…”
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A model for the investigation of factors influencing haemorrhagic necrosis mediated by tumour necrosis factor in tissue sites primed with mycobacterial antigen preparations by ATTIYAH, R., ROSEN, H., ROOK, G. A. W.

“…SUMMARY Mycobacterial lesions and skin sites challenged with soluble mycobacterial antigen are very sensitive to the necrotizing effect of tumour necrosis…”
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