Search Results - "RONDAS, Dieter"

Citrullinated glucose-regulated protein 78 is an autoantigen in type 1 diabetes by Rondas, Dieter, Crèvecoeur, Inne, D'Hertog, Wannes, Ferreira, Gabriela Bomfim, Staes, An, Garg, Abhishek D, Eizirik, Decio L, Agostinis, Patrizia, Gevaert, Kris, Overbergh, Lut, Mathieu, Chantal

“…Posttranslational modifications of self-proteins play a substantial role in the initiation or propagation of the autoimmune attack in several autoimmune…”
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Circulating tumor cell detection: A prospective comparison between CellSearch® and RareCyte® platforms in patients with progressive metastatic breast cancer by Dirix, Luc, Buys, Andy, Oeyen, Steffy, Peeters, Dieter, Liègeois, Vincent, Prové, Annemie, Rondas, Dieter, Vervoort, Liesbet, Mariën, Véronique, Laere, Steven Van, Vermeulen, Peter

“…Purpose Circulating tumor cells (CTCs) are prognostic in patients with breast cancer. Several technical platforms exist for their enumeration and…”
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Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells by Vig, Saurabh, Buitinga, Mijke, Rondas, Dieter, Crèvecoeur, Inne, van Zandvoort, Marc, Waelkens, Etienne, Eizirik, Decio L., Gysemans, Conny, Baatsen, Pieter, Mathieu, Chantal, Overbergh, Lut

“…The 78-kDa glucose-regulated protein (GRP78) is an ubiquitously expressed endoplasmic reticulum chaperone, with a central role in maintaining protein…”
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Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin by RONDAS, Dieter, TOMAS, Alejandra, HALBAN, Philippe A

“…Actin cytoskeleton remodeling is known to be involved in glucose-stimulated insulin secretion (GSIS). We have observed glucose-stimulated changes at the β-cell…”
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Foodborne cereulide causes beta-cell dysfunction and apoptosis by Vangoitsenhoven, Roman, Rondas, Dieter, Crèvecoeur, Inne, D'Hertog, Wannes, Baatsen, Pieter, Masini, Matilde, Andjelkovic, Mirjana, Van Loco, Joris, Matthys, Christophe, Mathieu, Chantal, Overbergh, Lut, Van der Schueren, Bart

“…To study the effects of cereulide, a food toxin often found at low concentrations in take-away meals, on beta-cell survival and function. Cell death was…”
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IL-17A increases the expression of proinflammatory chemokines in human pancreatic islets by Grieco, Fabio A., Moore, Fabrice, Vigneron, François, Santin, Izortze, Villate, Olatz, Marselli, Lorella, Rondas, Dieter, Korf, Hannelie, Overbergh, Lutgart, Dotta, Francesco, Marchetti, Piero, Mathieu, Chantal, Eizirik, Décio L.

“…Aims/hypothesis Cytotoxic T cells and macrophages contribute to beta cell destruction in type 1 diabetes at least in part through the production of cytokines…”
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1397 CDR404, an antibody-based bispecific & bivalent T-cell engager targeted against MAGE-A4, for Squamous Non-Small Cell Lung Cancer (SQ-NSCLC) by Vrohlings, Melissa, Jungmichel, Stephanie, Tosevski, Ivana, Vantellini, Alessio, Knobel, Philip, Sanchez, Nadia, Ross, Elizabeth, Kerckhoven, Marian Van, Giacomazzi, Giorgia, Liivrand, Maria, Hieta, Reija, Dupuis, Nicholas, Rondas, Dieter, Swatkowski, Pamela, Lenherr-Frey, Daniel, Biswas, Swethajit, Lopes, Gilberto, Borras, Leonardo

“…BackgroundSquamous non-small cell lung cancer (SQ-NSCLC) is the 2nd most common type of lung cancer. Given the paucity of actionable oncogene drivers, and lack…”
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Novel Mechanistic Link between Focal Adhesion Remodeling and Glucose-stimulated Insulin Secretion by Rondas, Dieter, Tomas, Alejandra, Soto-Ribeiro, Martinho, Wehrle-Haller, Bernhard, Halban, Philippe A.

“…Actin cytoskeleton remodeling is well known to be positively involved in glucose-stimulated pancreatic β cell insulin secretion. We have observed…”
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Abstract OT3-18-02: A comparative study of two detection platforms of circulating tumour cells in patients with metastatic breast cancer by Peeters, Dieter, Buys, Andy, Ledegen, Hannah, Moehlig, Kathlyn, Oeyen, Steffi, Rondas, Dieter, De Beukelaer, Alexia, Van Laere, Steven, Vervoort, Liesbet, Vermeulen, Peter, Ung, Christopher, Kockx, Mark, Dirix, Luc

“…Abstract Background: The enumeration of circulating tumour cells (CTCs) using the FDA-cleared CellSearch system has repeatedly been proven to bear prognostic…”
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The beta-cell in type 1 diabetes: What have we learned from proteomic studies? by Crèvecoeur, Inne, Rondas, Dieter, Mathieu, Chantal, Overbergh, Lut

“…Pancreatic beta‐cells have a crucial role in the regulation of blood glucose homeostasis by the production and secretion of insulin. In type 1 diabetes (T1D),…”
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Glucagon-Like Peptide‑1 Protects Human Islets against Cytokine-Mediated β‑Cell Dysfunction and Death: A Proteomic Study of the Pathways Involved by Rondas, Dieter, Bugliani, Marco, D’Hertog, Wannes, Lage, Kasper, Masini, Mathilde, Waelkens, Etienne, Marchetti, Piero, Mathieu, Chantal, Overbergh, Lut

“…Glucagon-like peptide-1 (GLP-1) has been shown to protect pancreatic β-cells against cytokine-induced dysfunction and destruction. The mechanisms through which…”
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Phosphorylation on Thr-106 and NO-modification of glyoxalase I suppress the TNF-induced transcriptional activity of NF-κB by de Hemptinne, Virginie, Rondas, Dieter, Toepoel, Mascha, Vancompernolle, Katia

“…Glyoxalase I (GLO1), together with glyoxalase II and the co-factor GSH, comprise the glyoxalase system, which is responsible for the detoxification of the…”
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A proteomic study of the regulatory role for STAT-1 in cytokine-induced beta-cell death by Rondas, Dieter, Gudmundsdottir, Valborg, D'Hertog, Wannes, Crèvecoeur, Inne, Waelkens, Etienne, Brunak, Soren, Mathieu, Chantal, Overbergh, Lut

“…Purpose Signal transducer and activator of transcription 1 (STAT‐1) plays a crucial role in cytokine‐induced beta‐cell destruction. However, its precise…”
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Tumour necrosis factor induces phosphorylation primarily of the nitric-oxide-responsive form of glyoxalase I by de Hemptinne, Virginie, Rondas, Dieter, Vandekerckhove, Joël, Vancompernolle, Katia

“…We have previously shown that TNF (tumour necrosis factor) induces phosphorylation of GLO1 (glyoxalase I), which is required for cell death in L929 cells. In…”
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Phosphorylation on Thr-106 and NO-modification of glyoxalase I suppress the TNF-induced transcriptional activity of NF-[kappa]B by de Hemptinne, Virginie, Rondas, Dieter, Toepoel, Mascha, Vancompernolle, Katia

“…Glyoxalase I (GLO1), together with glyoxalase II and the co-factor GSH, comprise the glyoxalase system, which is responsible for the detoxification of the…”
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Foodborne cereulide causes beta cell dysfunction and apoptosis by Vangoitsenhoven, Roman, Rondas, Dieter, Crèvecoeur, Inne, D'Hertog, Wannes, Masini, Matilde, Andjelkovic, Mirjana, Van Loco, Joris, Matthys, Christophe, Mathieu, Chantal, Overbergh, Lut, Van der Schueren, Bart

“…Subsequently, MIN6 cells were exposed to low concentrations of cereulide (0.15 - 0.5 ng/ml) for 24h and glucose-stimulated insulin secretion was evaluated as…”
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Phosphorylation on Thr-106 and NO-modification of glyoxalase I suppress the TNF-induced transcriptional activity of NF-kappaB by de Hemptinne, Virginie, Rondas, Dieter, Toepoel, Mascha, Vancompernolle, Katia

“…Glyoxalase I (GLO1), together with glyoxalase II and the co-factor GSH, comprise the glyoxalase system, which is responsible for the detoxification of the…”
Get full text