Search Results - "ROMANI, Rita"
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ANP and BNP Exert Anti-Inflammatory Action via NPR-1/cGMP Axis by Interfering with Canonical, Non-Canonical, and Alternative Routes of Inflammasome Activation in Human THP1 Cells
Published in International journal of molecular sciences (22-12-2020)“…Dysregulated inflammasome activation and interleukin (IL)-1β production are associated with several inflammatory disorders. Three different routes can lead to…”
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Extracellular Vesicles and the Inflammasome: An Intricate Network Sustaining Chemoresistance
Published in Frontiers in oncology (22-04-2022)“…Extracellular vesicles (EVs) are membrane enclosed spherical particles devoted to intercellular communication. Cancer-derived EVs (Ca-EVs) are deeply involved…”
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3
A New De Novo Missense Variant of the TET3 Gene in a Patient with Epilepsy and Macrocephaly
Published in International journal of molecular sciences (06-09-2024)“…The etiology of neurodevelopmental disorders and epilepsy is very heterogeneous and partly still unknown, and the research of causative genes related to these…”
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The Glyoxalase System Is a Novel Cargo of Amniotic Fluid Stem-Cell-Derived Extracellular Vesicles
Published in Antioxidants (01-08-2022)“…The glyoxalase system is a ubiquitous cellular metabolic pathway whose main physiological role is the removal of methylglyoxal (MG). MG, a glycolysis byproduct…”
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Microbiota-Associated HAF-EVs Regulate Monocytes by Triggering or Inhibiting Inflammasome Activation
Published in International journal of molecular sciences (28-01-2023)“…In pregnancy, human amniotic fluid extracellular vesicles (HAF-EVs) exert anti-inflammatory effects on T cells and on monocytes, supporting their…”
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Pharmacologic Induction of Endotoxin Tolerance in Dendritic Cells by L-Kynurenine
Published in Frontiers in immunology (11-03-2020)“…Endotoxin tolerance aims at opposing hyperinflammatory responses to lipopolysaccharide (LPS) exposure. The aryl hydrocarbon receptor (AhR) participates in…”
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Extracellular Vesicles in Aging: An Emerging Hallmark?
Published in Cells (Basel, Switzerland) (06-02-2023)“…Extracellular vesicles (EVs) are membrane-enclosed particles secreted by cells and circulating in body fluids. Initially considered as a tool to dispose of…”
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Amniotic fluid stem cell‐derived extracellular vesicles educate type 2 conventional dendritic cells to rescue autoimmune disorders in a multiple sclerosis mouse model
Published in Journal of extracellular vesicles (01-06-2024)“…Dendritic cells (DCs) are essential orchestrators of immune responses and represent potential targets for immunomodulation in autoimmune diseases. Human…”
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CpG Type A Induction of an Early Protective Environment in Experimental Multiple Sclerosis
Published in Mediators of Inflammation (01-01-2017)“…Experimental autoimmune encephalomyelitis (EAE) is an inflammatory, demyelinating disease of the CNS that mimics human multiple sclerosis (MS), and it is…”
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10
Deletion 2p15–16.1 syndrome: Case report and review
Published in American journal of medical genetics. Part A (01-10-2011)“…We report on a 9‐year‐old female patient with facial anomalies and developmental delay, heterozygous for three de novo rearrangements: a paracentric inversion…”
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Modulation of paraoxonase 1 and 3 expression after moderate exercise training in the rat
Published in Journal of lipid research (01-10-2009)“…Paraoxonases (PONs) are a small family of antioxidant enzymes whose antiatherogenic activity is well known. The aim of the present study was the evaluation of…”
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Expression of glyoxalase I and II in normal and breast cancer tissues
Published in Breast cancer research and treatment (01-03-2001)“…The present work aimed to study the activities of glyoxalase system enzymes, glyoxalase I (G I) and glyoxalase II (G II), as well as the expression of their…”
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Amniotic fluid stem cell‐derived extracellular vesicles are independent metabolic units capable of modulating inflammasome activation in THP‐1 cells
Published in The FASEB journal (01-04-2022)“…An immunoregulatory role of stem cells, often mediated by their secretome, has been claimed by several studies. Stem cell‐derived extracellular vesicles (EVs)…”
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Extracellular Vesicles-Mediated Transfer of miRNA Let-7b from PC3 Cells to Macrophages
Published in Genes (12-12-2020)“…Prostate-derived extracellular vesicles (pEVs) may represent a way to selectively transport cargo molecules from the producing cells to the target cells to…”
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S1P promotes migration, differentiation and immune regulatory activity in amniotic-fluid–derived stem cells
Published in European journal of pharmacology (15-08-2018)“…Stem cells have high potential for cell therapy in regenerative medicine. We previously isolated stem cell types from human amniotic fluid, derived from…”
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Recurrent ∼100 Kb microdeletion in the chromosomal region 14q11.2, involving CHD8 gene, is associated with autism and macrocephaly
Published in American journal of medical genetics. Part A (01-12-2014)“…The most frequent causes of Intellectual Disability (ID)/Autism Spectrum Disorders (ASDs) are chromosomal abnormalities, genomic rearrangements and…”
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Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3‐dioxygenase1
Published in Journal of cellular and molecular medicine (01-07-2015)“…Although human amniotic fluid does contain different populations of foetal‐derived stem cells, scanty information is available on the stemness and the…”
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18
CpG type-A induction of an early protective environment in experimental multiple sclerosis
Published in The Journal of immunology (1950) (01-05-2017)“…Abstract Experimental autoimmune encephalomyelitis (EAE) is an inflammatory, demyelinating disease of the CNS that mimics human multiple sclerosis (MS), and it…”
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19
LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism
Published in Immunobiology (1979) (01-02-2015)“…Abstract Dendritic cells (DCs) are specialized antigen-presenting cells with a bipolar nature. Depending on environmental factors, DCs will promote either…”
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Acetylcholinesterase at high catalytic efficiency and substrate specificity in the optic lobe of Eledone moschata (Cephalopoda: Octopoda): biochemical characterization and histochemical localization
Published in Neurochemistry international (01-08-1998)“…In the optic lobe of the cephalopod mollusc Eledone moschata, two acetylcholinesterase forms I and II were detected, both showing a marked active site…”
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