Search Results - "ROMANI, Chiara"
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1
Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial–mesenchymal transition
Published in Proceedings of the National Academy of Sciences - PNAS (25-10-2016)“…Carcinosarcomas (CSs) of the uterus and ovary are highly aggressive neoplasms containing both carcinomatous and sarcomatous elements. We analyzed the…”
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2
Prognosis and management of recurrent and/or metastatic head and neck adenoid cystic carcinoma
Published in Oral oncology (01-04-2021)“…•Adenoid cystic carcinoma is a rare tumor with a long-term prognosis.•Lack of clinical data about prognostic factors in recurrent/metastatic disease.•Clinical…”
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3
The expression level of VEGFR2 regulates mechanotransduction, tumor growth and metastasis of high grade serous ovarian cancer cells
Published in European journal of cell biology (01-12-2024)“…Recent data shows that alterations in the expression and/or activation of the vascular endothelial growth factor receptor 2 (VEGFR2) in high grade serous…”
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4
Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy
Published in Proceedings of the National Academy of Sciences - PNAS (05-11-2019)“…The prognosis of advanced/recurrent cervical cancer patients remains poor. We analyzed 54 fresh-frozen and 15 primary cervical cancer cell lines, along with…”
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5
Genome-wide study of salivary miRNAs identifies miR-423-5p as promising diagnostic and prognostic biomarker in oral squamous cell carcinoma
Published in Theranostics (2021)“…Survival rates of oral squamous cell carcinoma (OSCC) remained substantially unchanged over the last decades; thus, additional prognostic tools are strongly…”
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6
Functional profiles of curatively treated adenoid cystic carcinoma unveil prognostic features and potentially targetable pathways
Published in Scientific reports (31-01-2023)“…Adenoid cystic carcinoma (ACC) of salivary gland is a slowly growing tumor showing a propensity for delayed recurrence, with decreased survival rates. The…”
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Identification of stably expressed reference small non‐coding RNAs for microRNA quantification in high‐grade serous ovarian carcinoma tissues
Published in Journal of cellular and molecular medicine (01-12-2016)“…MicroRNAs (miRNAs) belong to a family of small non‐coding RNAs (sncRNAs) playing important roles in human carcinogenesis. Multiple investigations reported…”
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8
Epidermal growth factor receptor detection in serum and saliva as a diagnostic and prognostic tool in oral cancer
Published in The Laryngoscope (01-11-2017)“…Objectives/Hypothesis Epidermal growth factor receptor (EGFR) is a type I transmembrane glycoprotein that is overexpressed in a wide variety of malignancies,…”
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9
Immunotherapy for the prevention of high-risk oral disorders malignant transformation: the IMPEDE trial
Published in BMC cancer (17-05-2021)“…Oral Potentially Malignant Disorders (OPMD) have a non-negligible malignant transformation rate of up to 8%. Loss of heterozygosity (LOH) in critical…”
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10
FOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patients
Published in Journal of experimental & clinical cancer research (08-05-2017)“…Epithelial ovarian cancer (EOC) is a spectrum of different diseases, which makes their treatment a challenge. Forkhead box M1 (FOXM1) is an oncogene aberrantly…”
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11
VEGF-D Serum Level as a Potential Predictor of Lymph Node Metastasis and Prognosis in Vulvar Squamous Cell Carcinoma Patients
Published in Frontiers in oncology (08-04-2022)“…Radical surgical resection of the primary tumor with mono/bilateral inguinofemoral lymph node dissection is the standard treatment for invasive vulvar squamous…”
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12
New Challenges in Evaluating Outcomes after Immunotherapy in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma
Published in Vaccines (Basel) (01-06-2022)“…In many recurrent and/or metastatic cancers, the advent of immunotherapy opens up new scenarios of treatment response, with new phenomena, such as…”
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13
Pre-treatment Serum HE4 Level as a Novel Independent Prognostic Biomarker for Uterine Cervical Carcinoma Patients
Published in Frontiers in oncology (29-09-2020)“…In spite of the effective implementation of screening programs, uterine cervical carcinoma (UCC) remains one of the major causes of cancer death among women…”
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14
Low Expression of Claudin-7 as Potential Predictor of Distant Metastases in High-Grade Serous Ovarian Carcinoma Patients
Published in Frontiers in oncology (04-08-2020)“…High-grade serous ovarian carcinoma (HGSOC) usually spreads directly into the peritoneal cavity following a transcoelomic dissemination route, although distant…”
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15
Clinical and Histological Prognostic Factors of Recurrence and Malignant Transformation in a Large Series of Oral Potentially Malignant Disorders
Published in Frontiers in oncology (21-04-2022)“…Oral potentially malignant disorders (OPMDs) represent a heterogeneous set of different histological lesions, characterized by the capacity to transform in…”
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16
Identification of optimal reference genes for gene expression normalization in a wide cohort of endometrioid endometrial carcinoma tissues
Published in PloS one (04-12-2014)“…Accurate normalization is a primary component of a reliable gene expression analysis based on qRT-PCR technique. While the use of one or more reference genes…”
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MAL gene overexpression as a marker of high-grade serous ovarian carcinoma stem-like cells that predicts chemoresistance and poor prognosis
Published in BMC cancer (25-05-2017)“…The existence of cancer stem cells (CSCs) within a tumor bulk has been demonstrated for many solid tumors including epithelial ovarian carcinoma (EOC). CSCs…”
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18
Gene Expression Clustering and Selected Head and Neck Cancer Gene Signatures Highlight Risk Probability Differences in Oral Premalignant Lesions
Published in Cells (Basel, Switzerland) (03-08-2020)“…Oral premalignant lesions (OPLs) represent the most common oral precancerous conditions. One of the major challenges in this field is the identification of…”
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19
Development and characterization of a human single-chain antibody fragment against claudin-3: a novel therapeutic target in ovarian and uterine carcinomas
Published in American journal of obstetrics and gynecology (01-07-2009)“…Objective The purpose of this study was to develop and characterize a human antibody in a single-chain antibody fragment format (scFv) that is directed…”
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Human Papillomavirus Type 16 (HPV-16) Virus-Like Particle L1-Specific CD8+ Cytotoxic T Lymphocytes (CTLs) Are Equally Effective as E7-Specific CD8+ CTLs in Killing Autologous HPV-16-Positive Tumor Cells in Cervical Cancer Patients: Implications for L1 Dendritic Cell-Based Therapeutic Vaccines
Published in Journal of Virology (01-07-2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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