Search Results - "ROM, William N"
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microRNAs derived from circulating exosomes as noninvasive biomarkers for screening and diagnosing lung cancer
Published in Journal of thoracic oncology (01-09-2013)“…Lung cancer is the highest cause of mortality among tumor pathologies worldwide. There are no validated techniques for an early detection of pulmonary cancer…”
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A Panel of Novel Detection and Prognostic Methylated DNA Markers in Primary Non-Small Cell Lung Cancer and Serum DNA
Published in Clinical cancer research (15-11-2017)“…To establish a novel panel of cancer-specific methylated genes for cancer detection and prognostic stratification of early-stage non-small cell lung cancer…”
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3
Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancer
Published in PloS one (07-12-2010)“…Lung cancer is the leading cause of cancer deaths worldwide. New diagnostics are needed to detect early stage lung cancer because it may be cured with surgery…”
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Blinded Validation of Breath Biomarkers of Lung Cancer, a Potential Ancillary to Chest CT Screening
Published in PloS one (23-12-2015)“…Breath volatile organic compounds (VOCs) have been reported as biomarkers of lung cancer, but it is not known if biomarkers identified in one group can…”
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Differential N‑Glycosylation Patterns in Lung Adenocarcinoma Tissue
Published in Journal of proteome research (06-11-2015)“…To decrease the mortality of lung cancer, better screening and diagnostic tools as well as treatment options are needed. Protein glycosylation is one of the…”
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Differential role for CD80 and CD86 in the regulation of the innate immune response in murine polymicrobial sepsis
Published in PloS one (12-08-2009)“…Inflammation in the early stages of sepsis is governed by the innate immune response. Costimulatory molecules are a receptor/ligand class of molecules capable…”
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Metabolomic markers of altered nucleotide metabolism in early stage adenocarcinoma
Published in Cancer prevention research (Philadelphia, Pa.) (01-05-2015)“…Adenocarcinoma, a type of non-small cell lung cancer, is the most frequently diagnosed lung cancer and the leading cause of lung cancer mortality in the United…”
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Detection of lung cancer using weighted digital analysis of breath biomarkers
Published in Clinica chimica acta (17-07-2008)“…A combination of biomarkers in a multivariate model may predict disease with greater accuracy than a single biomarker employed alone. We developed a non-linear…”
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Identification of autoantibodies to ECH1 and HNRNPA2B1 as potential biomarkers in the early detection of lung cancer
Published in Oncoimmunology (04-05-2017)“…Identification of biomarkers for early detection of lung cancer (LC) is important, in turn leading to more effective treatment and reduction of mortality…”
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Case series report of a linezolid-containing regimen for extensively drug-resistant tuberculosis
Published in Chest (01-07-2008)“…To determine whether linezolid is safe and well tolerated in the treatment of extensively drug-resistant tuberculosis (XDR-TB). The was conducted in a…”
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Value of metalloproteinases in predicting COPD in heavy urban smokers
Published in Respiratory research (02-09-2020)“…Emphysema in asymptomatic heavy smokers can be detected during CT-scan screening for lung cancer. Metalloproteinases (MMPs) have been found to play a role in…”
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Detection of lung cancer with volatile markers in the breath
Published in Chest (01-06-2003)“…To evaluate volatile organic compounds (VOCs) in the breath as tumor markers in lung cancer. Alkanes and monomethylated alkanes are oxidative stress products…”
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Variant Ciz1 is a circulating biomarker for early-stage lung cancer
Published in Proceedings of the National Academy of Sciences - PNAS (06-11-2012)“…There is an unmet need for circulating biomarkers that can detect early-stage lung cancer. Here we show that a variant form of the nuclear matrix-associated…”
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Obstructive airways disease with air trapping among firefighters exposed to World Trade Center dust
Published in Chest (01-03-2010)“…The World Trade Center (WTC) collapse produced a massive exposure to respirable particulates in New York City Fire Department (FDNY) rescue workers. This group…”
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Distal airway function in symptomatic subjects with normal spirometry following World Trade Center dust exposure
Published in Chest (01-10-2007)“…Following collapse of the World Trade Center (WTC), individuals reported new-onset respiratory symptoms. Despite symptoms, spirometry often revealed normal…”
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Adenosine deaminase acting on RNA-1 (ADAR1) inhibits HIV-1 replication in human alveolar macrophages
Published in PloS one (01-10-2014)“…While exploring the effects of aerosol IFN-γ treatment in HIV-1/tuberculosis co-infected patients, we observed A to G mutations in HIV-1 envelope sequences…”
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Inflammatory Biomarkers Predict Airflow Obstruction After Exposure to World Trade Center Dust
Published in Chest (01-08-2012)“…Background The World Trade Center (WTC) collapse on September 11, 2001, produced airflow obstruction in a majority of firefighters receiving subspecialty…”
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Identification of Annexin 1 as a Novel Autoantigen in Acute Exacerbation of Idiopathic Pulmonary Fibrosis
Published in The Journal of immunology (1950) (01-07-2008)“…Consistent with the hypothesis that pulmonary epithelial apoptosis is the key to the acute exacerbation of idiopathic pulmonary fibrosis (IPF), we conducted…”
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Cough and Bronchial Responsiveness in Firefighters at the World Trade Center Site
Published in The New England journal of medicine (12-09-2002)“…The collapse of and fires at the World Trade Center in New York on September 11, 2001, resulted in large quantities of airborne material. The authors report on…”
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Annals of Education: Teaching Climate Change and Global Public Health
Published in International journal of environmental research and public health (27-12-2023)“…The climate crisis is a health emergency: breaking temperature records every successive month, increasing mortality from hurricanes/cyclones resulting in…”
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