Search Results - "ROM, William N"

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  1. 1

    microRNAs derived from circulating exosomes as noninvasive biomarkers for screening and diagnosing lung cancer by Cazzoli, Riccardo, Buttitta, Fiamma, Di Nicola, Marta, Malatesta, Sara, Marchetti, Antonio, Rom, William N, Pass, Harvey I

    Published in Journal of thoracic oncology (01-09-2013)
    “…Lung cancer is the highest cause of mortality among tumor pathologies worldwide. There are no validated techniques for an early detection of pulmonary cancer…”
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  2. 2

    A Panel of Novel Detection and Prognostic Methylated DNA Markers in Primary Non-Small Cell Lung Cancer and Serum DNA by Ooki, Akira, Maleki, Zahra, Tsay, Jun-Chieh J, Goparaju, Chandra, Brait, Mariana, Turaga, Nitesh, Nam, Hae-Seong, Rom, William N, Pass, Harvey I, Sidransky, David, Guerrero-Preston, Rafael, Hoque, Mohammad Obaidul

    Published in Clinical cancer research (15-11-2017)
    “…To establish a novel panel of cancer-specific methylated genes for cancer detection and prognostic stratification of early-stage non-small cell lung cancer…”
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  3. 3

    Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancer by Ostroff, Rachel M, Bigbee, William L, Franklin, Wilbur, Gold, Larry, Mehan, Mike, Miller, York E, Pass, Harvey I, Rom, William N, Siegfried, Jill M, Stewart, Alex, Walker, Jeffrey J, Weissfeld, Joel L, Williams, Stephen, Zichi, Dom, Brody, Edward N

    Published in PloS one (07-12-2010)
    “…Lung cancer is the leading cause of cancer deaths worldwide. New diagnostics are needed to detect early stage lung cancer because it may be cured with surgery…”
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  4. 4

    Blinded Validation of Breath Biomarkers of Lung Cancer, a Potential Ancillary to Chest CT Screening by Phillips, Michael, Bauer, Thomas L, Cataneo, Renee N, Lebauer, Cassie, Mundada, Mayur, Pass, Harvey I, Ramakrishna, Naren, Rom, William N, Vallières, Eric

    Published in PloS one (23-12-2015)
    “…Breath volatile organic compounds (VOCs) have been reported as biomarkers of lung cancer, but it is not known if biomarkers identified in one group can…”
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  5. 5

    Differential N‑Glycosylation Patterns in Lung Adenocarcinoma Tissue by Ruhaak, L. Renee, Taylor, Sandra L, Stroble, Carol, Nguyen, Uyen Thao, Parker, Evan A, Song, Ting, Lebrilla, Carlito B, Rom, William N, Pass, Harvey, Kim, Kyoungmi, Kelly, Karen, Miyamoto, Suzanne

    Published in Journal of proteome research (06-11-2015)
    “…To decrease the mortality of lung cancer, better screening and diagnostic tools as well as treatment options are needed. Protein glycosylation is one of the…”
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  6. 6

    Differential role for CD80 and CD86 in the regulation of the innate immune response in murine polymicrobial sepsis by Nolan, Anna, Kobayashi, Hiroshi, Naveed, Bushra, Kelly, Ann, Hoshino, Yoshihiko, Hoshino, Satomi, Karulf, Matthew R, Rom, William N, Weiden, Michael D, Gold, Jeffrey A

    Published in PloS one (12-08-2009)
    “…Inflammation in the early stages of sepsis is governed by the innate immune response. Costimulatory molecules are a receptor/ligand class of molecules capable…”
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  7. 7

    Metabolomic markers of altered nucleotide metabolism in early stage adenocarcinoma by Wikoff, William R, Grapov, Dmitry, Fahrmann, Johannes F, DeFelice, Brian, Rom, William N, Pass, Harvey I, Kim, Kyoungmi, Nguyen, UyenThao, Taylor, Sandra L, Gandara, David R, Kelly, Karen, Fiehn, Oliver, Miyamoto, Suzanne

    “…Adenocarcinoma, a type of non-small cell lung cancer, is the most frequently diagnosed lung cancer and the leading cause of lung cancer mortality in the United…”
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  8. 8

    Detection of lung cancer using weighted digital analysis of breath biomarkers by Phillips, Michael, Altorki, Nasser, Austin, John H.M., Cameron, Robert B., Cataneo, Renee N., Kloss, Robert, Maxfield, Roger A., Munawar, Muhammad I., Pass, Harvey I., Rashid, Asif, Rom, William N., Schmitt, Peter, Wai, James

    Published in Clinica chimica acta (17-07-2008)
    “…A combination of biomarkers in a multivariate model may predict disease with greater accuracy than a single biomarker employed alone. We developed a non-linear…”
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  9. 9

    Identification of autoantibodies to ECH1 and HNRNPA2B1 as potential biomarkers in the early detection of lung cancer by Dai, Liping, Li, Jitian, Tsay, Jun-Chieh J., Yie, Ting-An, Munger, John S., Pass, Harvey, Rom, William N., Tan, Eng M., Zhang, Jian-Ying

    Published in Oncoimmunology (04-05-2017)
    “…Identification of biomarkers for early detection of lung cancer (LC) is important, in turn leading to more effective treatment and reduction of mortality…”
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  10. 10

    Case series report of a linezolid-containing regimen for extensively drug-resistant tuberculosis by Condos, Rany, Hadgiangelis, Nicos, Leibert, Eric, Jacquette, Germaine, Harkin, Timothy, Rom, William N

    Published in Chest (01-07-2008)
    “…To determine whether linezolid is safe and well tolerated in the treatment of extensively drug-resistant tuberculosis (XDR-TB). The was conducted in a…”
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  11. 11

    Value of metalloproteinases in predicting COPD in heavy urban smokers by Tsay, Jun-Chieh J, Hu, Yingjie, Goldberg, Judith D, Wang, Bin, Vijayalekshmy, Soumya, Yie, Ting-An, Bantis, Katrina, Sterman, Daniel H, Rom, William N

    Published in Respiratory research (02-09-2020)
    “…Emphysema in asymptomatic heavy smokers can be detected during CT-scan screening for lung cancer. Metalloproteinases (MMPs) have been found to play a role in…”
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  12. 12

    Detection of lung cancer with volatile markers in the breath by Phillips, Michael, Cataneo, Renee N, Cummin, Andrew R C, Gagliardi, Anthony J, Gleeson, Kevin, Greenberg, Joel, Maxfield, Roger A, Rom, William N

    Published in Chest (01-06-2003)
    “…To evaluate volatile organic compounds (VOCs) in the breath as tumor markers in lung cancer. Alkanes and monomethylated alkanes are oxidative stress products…”
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  13. 13

    Variant Ciz1 is a circulating biomarker for early-stage lung cancer by Higgins, Gillian, Roper, Katherine M, Watson, Irene J, Blackhall, Fiona H, Rom, William N, Pass, Harvey I, Ainscough, Justin F. X, Coverley, Dawn

    “…There is an unmet need for circulating biomarkers that can detect early-stage lung cancer. Here we show that a variant form of the nuclear matrix-associated…”
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  14. 14

    Obstructive airways disease with air trapping among firefighters exposed to World Trade Center dust by Weiden, Michael D, Ferrier, Natalia, Nolan, Anna, Rom, William N, Comfort, Ashley, Gustave, Jackson, Zeig-Owens, Rachel, Zheng, Shugi, Goldring, Roberta M, Berger, Kenneth I, Cosenza, Kaitlyn, Lee, Roy, Webber, Mayris P, Kelly, Kerry J, Aldrich, Thomas K, Prezant, David J

    Published in Chest (01-03-2010)
    “…The World Trade Center (WTC) collapse produced a massive exposure to respirable particulates in New York City Fire Department (FDNY) rescue workers. This group…”
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  15. 15

    Distal airway function in symptomatic subjects with normal spirometry following World Trade Center dust exposure by Oppenheimer, Beno W, Goldring, Roberta M, Herberg, Matthew E, Hofer, Ira S, Reyfman, Paul A, Liautaud, Sybille, Rom, William N, Reibman, Joan, Berger, Kenneth I

    Published in Chest (01-10-2007)
    “…Following collapse of the World Trade Center (WTC), individuals reported new-onset respiratory symptoms. Despite symptoms, spirometry often revealed normal…”
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  16. 16

    Adenosine deaminase acting on RNA-1 (ADAR1) inhibits HIV-1 replication in human alveolar macrophages by Weiden, Michael D, Hoshino, Satomi, Levy, David N, Li, Yonghua, Kumar, Rajnish, Burke, Sean A, Dawson, Rodney, Hioe, Catarina E, Borkowsky, William, Rom, William N, Hoshino, Yoshihiko

    Published in PloS one (01-10-2014)
    “…While exploring the effects of aerosol IFN-γ treatment in HIV-1/tuberculosis co-infected patients, we observed A to G mutations in HIV-1 envelope sequences…”
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    Identification of Annexin 1 as a Novel Autoantigen in Acute Exacerbation of Idiopathic Pulmonary Fibrosis by Kurosu, Katsushi, Takiguchi, Yuichi, Okada, Osamu, Yumoto, Norio, Sakao, Seiichiro, Tada, Yuji, Kasahara, Yasunori, Tanabe, Nobuhiro, Tatsumi, Koichiro, Weiden, Michael, Rom, William N, Kuriyama, Takayuki

    Published in The Journal of immunology (1950) (01-07-2008)
    “…Consistent with the hypothesis that pulmonary epithelial apoptosis is the key to the acute exacerbation of idiopathic pulmonary fibrosis (IPF), we conducted…”
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  19. 19

    Cough and Bronchial Responsiveness in Firefighters at the World Trade Center Site by Prezant, David J, Weiden, Michael, Banauch, Gisela I, McGuinness, Georgeann, Rom, William N, Aldrich, Thomas K, Kelly, Kerry J

    Published in The New England journal of medicine (12-09-2002)
    “…The collapse of and fires at the World Trade Center in New York on September 11, 2001, resulted in large quantities of airborne material. The authors report on…”
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  20. 20

    Annals of Education: Teaching Climate Change and Global Public Health by Rom, William N

    “…The climate crisis is a health emergency: breaking temperature records every successive month, increasing mortality from hurricanes/cyclones resulting in…”
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