Search Results - "ROLS, M. P"

First explanations for differences in electrotransfection efficiency in vitro and in vivo using spheroid model by Chopinet, L., Wasungu, L., Rols, M.-P.

“…Electro-gene-therapy is a promising technique for cancer treatment. However, knowledge about mechanism of gene transfer with electric field in tumor is…”
Get full text

Direct visualization at the single-cell level of siRNA electrotransfer into cancer cells by Paganin-Gioanni, A, Bellard, E, Escoffre, J.M, Rols, M.P, Teissié, J, Golzio, M

“…The RNA interference-mediated gene silencing approach is promising for therapies based on the targeted inhibition of disease-relevant genes…”
Get full text

Electrically-assisted nucleic acids delivery to tissues in vivo: where do we stand? by Cemazar, M, Golzio, M, Sersa, G, Rols, M P, Teissié, J

“…Electropulsation (electroporation) is a physical method for delivery of various molecules into the cells in vitro and in vivo. It is an expanding field due to…”
Get more information

Mechanisms of cell membrane electropermeabilization: A minireview of our present (lack of ?) knowledge by Teissie, J., Golzio, M., Rols, M.P.

“…Cell electropulsation is routinely used in cell Biology for protein, RNA or DNA transfer. Its clinical applications are under development for targeted drug…”
Get full text

Control by pulse parameters of DNA electrotransfer into solid tumors in mice by Cemazar, M, Golzio, M, Sersa, G, Hojman, P, Kranjc, S, Mesojednik, S, Rols, M-P, Teissie, J

“…Electrotransfer (electroporation) is recognized as one of the most promising alternatives to viral vectors for transfection of different tissues in vivo for…”
Get full text

Successful treatment of equine sarcoids with cisplatin electrochemotherapy: A retrospective study of 48 cases by TAMZALI, Y., BORDE, L., ROLS, M. P., GOLZIO, M., LYAZRHI, F., TEISSIE, J.

“…Summary Reasons for performing study: Sarcoids are the commonest form of equine skin tumour. Several therapeutic measures have been described but none is…”
Get full text

A 3D in vitro spheroid model as a way to study the mechanisms of electroporation by Wasungu, L., Escoffre, J.-M., Valette, A., Teissie, J., Rols, M.-P.

“…Electropermeabilization is a physical method to deliver molecules into cells and tissues. Clinical applications have been successfully developed for…”
Get full text

Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery by GOLZIO, M, MAZZOLINI, L, MOLLER, P, ROLS, M. P, TEISSIE, J

“…Owing to their capacity to induce strong, sequence-specific, gene silencing in cells, short interfering RNAs (siRNAs) represent new potential therapeutic…”
Get full text

In vivo electrically mediated protein and gene transfer in murine melanoma by Rols, Marie-Pierre, Delteil, Christine, Golzio, Muriel, Dumond, Patrick, Cros, Suzie, Teissie, Justin

“…We show that efficient permeabilization of murine melanoma can be obtained in vivo by applying electric pulses. More than 80% of the cell population is…”
Get full text

In Vitro Gene Transfer by Electrosonoporation by Escoffre, J.M, Kaddur, K, Rols, M.P, Bouakaz, A

“…Abstract Among the nonviral methods for gene delivery in vitro , electroporation is simple, inexpensive and safe. To upregulate the expression level of…”
Get full text

Effective treatment of cutaneous and subcutaneous malignant tumours by electrochemotherapy by MIR, L. M, GLASS, L. F, BELEHRADEK, M, GILBERT, R, ROLS, M.-P, BELEHRADEK, J. JR, BACHAUD, J. M, DECONTI, R, STABUC, B, CEMAZAR, M, CONINX, P, HELLER, R, SERSA, G, TEISSIE, J, DOMENGE, C, MIKLAVCIC, D, JAROSZESKI, M. J, ORLOWSKA, S, REINTGEN, D. S, RUDOLF, Z

“…Electrochemotherapy (ECT) enhances the effectiveness of chemotherapeutic agents by administering the drug in combination with short intense electric pulses…”
Get full text

Optical imaging of in vivo gene expression: a critical assessment of the methodology and associated technologies by Golzio, M, Rols, M-P, Gabriel, B, Teissié, J

“…Following and quantifying the expression of reporter gene expression in vivo is very important to monitor the expression of therapeutic genes in targeted…”
Get full text

Pre-treatment of cells with pluronic L64 increases DNA transfection mediated by electrotransfer by Wasungu, L., Marty, A.L., Bureau, M.F., Kichler, A., Bessodes, M., Teissie, J., Scherman, D., Rols, M.P., Mignet, N.

“…Gene transfer into muscle cells is a key issue in biomedical research. Indeed, it is important for the development of new therapy for many genetic disorders…”
Get full text

In vitro and in vivo electric field-mediated permeabilization, gene transfer, and expression by Golzio, M, Rols, M.P, Teissié, J

“…Electropulsation is one of the non-viral methods successfully used to transfer genes into living cells in vitro as in vivo. This approach shows promise in the…”
Get full text

An experimental evaluation of the critical potential difference inducing cell membrane electropermeabilization by Teissié, J., Rols, M.P.

“…When applied on intact cell suspension, electric field pulses are known to induce membrane permeabilization (electropermeabilization) and fusion…”
Get full text

Electropermeabilization of cell membranes by Teissié, J, Eynard, N, Gabriel, B, Rols, M.P

“…A position dependent modulation of the membrane potential difference is induced when an electric field is applied to a cell. When cells are submitted to short…”
Get full text

Membrane perturbation by an external electric field: a mechanism to permit molecular uptake by Escoffre, J-M, Dean, D S, Hubert, M, Rols, M-P, Favard, C

“…Electropermeabilisation is a well established physical method, based on the application of electric pulses, which induces the transient permeabilisation of the…”
Get full text

Electrochemotherapy of cutaneous metastases in malignant melanoma by Rols, M P, Bachaud, J M, Giraud, P, Chevreau, C, Roché, H, Teissié, J

“…Electrochemotherapy is a new anticancer therapy in which transient permeabilization of cells by an electric field induces a significant increase in the…”
Get full text

Imaging living cells surface and quantifying its properties at high resolution using AFM in QI™ mode by Chopinet, L., Formosa, C., Rols, M.P., Duval, R.E., Dague, E.

“…► This paper presents results obtained using the AFM quantitative imaging mode. ► We explored the surface topography, nanomechanical or adhesion properties of…”
Get full text

Electropermeabilization of mammalian cells. Quantitative analysis of the phenomenon by Rols, M.P., Teissié, J.

“…Transient membrane permeabilization by application of high electric field intensity pulses on cells (electropermeabilization) depends on several physical…”
Get full text