Search Results - "ROIVAINEN, M."

Role of environmental poliovirus surveillance in global polio eradication and beyond by HOVI, T., SHULMAN, L. M., VAN DER AVOORT, H., DESHPANDE, J., ROIVAINEN, M., DE GOURVILLE, E. M.

“…Environmental poliovirus surveillance (ENV) means monitoring of poliovirus (PV) transmission in human populations by examining environmental specimens…”
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Multiple norovirus outbreaks linked to imported frozen raspberries by SARVIKIVI, E., ROIVAINEN, M., MAUNULA, L., NISKANEN, T., KORHONEN, T., LAPPALAINEN, M., KUUSI, M.

“…In 2009, the number of foodborne norovirus outbreaks in Finland seemed markedly high, and many outbreaks seemed to be linked to imported frozen raspberries. We…”
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Association of Recombination Events in the Founding and Emergence of Subgenogroup Evolutionary Lineages of Human Enterovirus 71 by McWilliam Leitch, E. C, Cabrerizo, M, Cardosa, J, Harvala, H, Ivanova, O. E, Koike, S, Kroes, A. C. M, Lukashev, A, Perera, D, Roivainen, M, Susi, P, Trallero, G, Evans, D. J, Simmonds, P

“…Enterovirus 71 (EV71) is responsible for frequent large-scale outbreaks of hand, foot, and mouth disease worldwide and represent a major etiological agent of…”
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Evolutionary Dynamics and Temporal/Geographical Correlates of Recombination in the Human Enterovirus Echovirus Types 9, 11, and 30 by McWilliam Leitch, E C, Cabrerizo, M, Cardosa, J, Harvala, H, Ivanova, O E, Kroes, A C M, Lukashev, A, Muir, P, Odoom, J, Roivainen, M, Susi, P, Trallero, G, Evans, D J, Simmonds, P

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Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells by YLIPAASTO, P, KLINGEL, K, LINDBERG, A. M, OTONKOSKI, T, KANDOLF, R, HOVI, T, ROIVAINEN, M

“…It is thought that enterovirus infections cause beta-cell damage and contribute to the development of Type 1 diabetes by replicating in the pancreatic islets…”
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Transmission Networks and Population Turnover of Echovirus 30 by McWilliam Leitch, E C, Bendig, J, Cabrerizo, M, Cardosa, J, Hyypiä, T, Ivanova, O E, Kelly, A, Kroes, A C M, Lukashev, A, MacAdam, A, McMinn, P, Roivainen, M, Trallero, G, Evans, D J, Simmonds, P

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Role of enteroviruses in the pathogenesis of type 1 diabetes by Roivainen, M., Klingel, K.

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Enterovirus-induced gene expression profile is critical for human pancreatic islet destruction by Ylipaasto, P., Smura, T., Gopalacharyulu, P., Paananen, A., Seppänen-Laakso, T., Kaijalainen, S., Ahlfors, H., Korsgren, O., Lakey, J. R. T., Lahesmaa, R., Piemonti, L., Oresic, M., Galama, J., Roivainen, M.

“…Aims/hypothesis Virally induced inflammatory responses, beta cell destruction and release of beta cell autoantigens may lead to autoimmune reactions…”
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Human enterovirus infections in children at increased risk for type 1 diabetes: the Babydiet study by Simonen-Tikka, M.-L., Pflueger, M., Klemola, P., Savolainen-Kopra, C., Smura, T., Hummel, S., Kaijalainen, S., Nuutila, K., Natri, O., Roivainen, M., Ziegler, A.-G.

“…Aims/hypothesis The aim of this study was to examine human enteroviruses (HEVs) and other intestinal viruses derived from children who participated in the…”
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Symmetry-Related Clustering of Positive Charges Is a Common Mechanism for Heparan Sulfate Binding in Enteroviruses by MCLEISH, Nigel J, WILLIAMS, Cigdem H, KALOUDAS, Dimitrios, ROIVAINEN, Merja M, STANWAY, Glyn

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Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets by YLIPAASTO, P, KUTLU, B, OTONKOSKI, T, ROIVAINEN, M, RASILAINEN, S, RASSCHAERT, J, SALMELA, K, TEERIJOKI, H, KORSGREN, O, LAHESMAA, R, HOVI, T, EIZIRIK, D. L

“…It is thought that enterovirus infections initiate or facilitate the pathogenetic processes leading to type 1 diabetes. Exposure of cultured human islets to…”
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Detection of human norovirus from frozen raspberries in a cluster of gastroenteritis outbreaks by Maunula, L, Roivainen, M, Keränen, M, Mäkela, S, Söderberg, K, Summa, M, von Bonsdorff, C H, Lappalainen, M, Korhonen, T, Kuusi, M, Niskanen, T

“…We describe a cluster of norovirus outbreaks affecting about 200 people in Southern Finland in September and October 2009. All outbreaks occurred after…”
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No evidence of enteroviruses in the intestine of patients with type 1 diabetes by Mercalli, A., Lampasona, V., Klingel, K., Albarello, L., Lombardoni, C., Ekström, J., Sordi, V., Bolla, A., Mariani, A., Bzhalava, D., Dillner, J., Roivainen, M., Bosi, E., Piemonti, L.

“…Aims/hypothesis The purpose of this study was to investigate whether the gut mucosa is a reservoir for enterovirus persistence in patients with type 1…”
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Environmental surveillance of viruses by tangential flow filtration and metagenomic reconstruction by Furtak, Vyacheslav, Roivainen, Merja, Mirochnichenko, Olga, Zagorodnyaya, Tatiana, Laassri, Majid, Zaidi, Sohail Z, Rehman, Lubna, Alam, Muhammad M, Chizhikov, Vladimir, Chumakov, Konstantin

“…An approach is proposed for environmental surveillance of poliovirus by concentrating sewage samples with tangential flow filtration (TFF) followed by deep…”
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A single amino acid substitution in viral VP1 protein alters the lytic potential of clone-derived variants of echovirus 9 DM strain in human pancreatic islets by Paananen, A., Ylipaasto, P., Smura, T., Lempinen, M., Galama, J., Roivainen, M.

“…In vitro studies with primary human pancreatic islets suggest that several enterovirus serotypes are able to infect and replicate in beta cells. Some…”
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Outbreak of gastroenteritis caused by norovirus GII.4 Sydney variant after a wedding reception at a resort/activity centre, Finland, August 2012 by POLKOWSKA, A., RÖNNQVIST, M., LEPISTÖ, O., ROIVAINEN, M., MAUNULA, L., HUUSKO, S., TOIKKANEN, S., RIMHANEN-FINNE, R.

“…In August 2012, an outbreak of gastroenteritis occurred among 88 persons attending a wedding reception at a resort/activity centre in Ylöjärvi, Finland. Of 39…”
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Probiotics and respiratory and gastrointestinal tract infections in Finnish military conscripts - a randomised placebo-controlled double-blinded study by Kalima, K, Lehtoranta, L, He, L, Pitkäniemi, J, Lundell, R, Julkunen, I, Roivainen, M, Närkiö, M, Mäkelä, M J, Siitonen, S, Korpela, R, Pitkäranta, A

“…Military conscripts are susceptible to respiratory and gastrointestinal tract infections. In previous studies probiotics have shown potency to reduce upper…”
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Functional impairment and killing of human beta cells by enteroviruses: the capacity is shared by a wide range of serotypes, but the extent is a characteristic of individual virus strains by Roivainen, M, Ylipaasto, P, Savolainen, C, Galama, J, Hovi, T, Otonkoski, T

“…Direct infection of beta cells could explain the diabetogenic effect of enteroviruses. Primary adult human beta cells are susceptible to coxsackievirus…”
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Antibodies to the vitronectin receptor (integrin alpha V beta 3) inhibit binding and infection of foot-and-mouth disease virus to cultured cells by Berinstein, A, Roivainen, M, Hovi, T, Mason, P W, Baxt, B

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CCR5 deficiency and severe polio infection in the 1984 outbreak in Finland by Rosenberg, A.S., Roivainen, M., Hovi, T., Liu, Q., Murphy, P.M.

“…CCR5, a leukocyte chemoattractant receptor for chemokines CCL3, CCL4, and CCL5, promotes innate and adaptive immune responses by mediating leukocyte…”
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