Search Results - "ROHN, J. L"

Ultrasound-activated microbubbles as a novel intracellular drug delivery system for urinary tract infection by Horsley, H, Owen, J, Browning, R, Carugo, D, Malone-Lee, J, Stride, E, Rohn, J L

“…The development of new modalities for high-efficiency intracellular drug delivery is a priority for a number of disease areas. One such area is urinary tract…”
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Human death effector domain-associated factor interacts with the viral apoptosis agonist Apoptin and exerts tumor-preferential cell killing by Danen-van Oorschot, A A A M, Voskamp, P, Seelen, M C M J, van Miltenburg, M H A M, Bolk, M W, Tait, S W, Boesen-de Cock, J G R, Rohn, J L, Borst, J, Noteborn, M H M

“…Apoptin, a protein from chicken anemia virus without an apparent cellular homologue, can induce apoptosis in mammalian cells. Its cytotoxicity is limited to…”
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The viral death effector Apoptin reveals tumor-specific processes by Rohn, J L, Noteborn, M H M

“…Several natural proteins, including the cellular protein TRAIL and the viral proteins E4orf4 and Apoptin, have been found to exert a tumor-preferential…”
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Relevance of apoptin's integrity for its functional behavior by Rohn, J L, Zhang, Y-H, Leliveld, S R, Danen-van Oorschot, A A A M, Henriquez, N V, Abrahams, J P, Noteborn, M H M

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Apoptin’s functional N- and C-termini independently bind DNA by Leliveld, S.R, Dame, R.T, Rohn, J.L, Noteborn, M.H.M, Abrahams, J.P

“…Apoptin induces apoptosis specifically in tumour cells, where Apoptin is enriched in the DNA-dense heterochromatin and nucleoli. In vitro, Apoptin interacts…”
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Transduction of Notch2 in feline leukemia virus-induced thymic lymphoma by Rohn, J.L. (University of Washington, Seattle, WA.), Lauring, A.S, Linenberger, M.L, Overbaugh, J

“…Feline leukemia virus (FeLV) is thought to induce neoplastic diseases in infected cats by a variety of mechanisms, including the transduction of host…”
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The opposing roles of the Akt and c-Myc signalling pathways in survival from CD95-mediated apoptosis by ROHN, J. L, HUEBER, A.-O, MCCARTHY, N. J, LYON, D, NAVARRO, P, BURGERING, B. M. T, EVAN, G. I

“…Expression of the proto-oncogene c-myc stimulates cell proliferation in the presence of the appropriate survival factors and triggers apoptosis in their…”
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Evolution of feline leukemia virus variant genomes with insertions, deletions, and defective envelope genes in infected cats with tumors by ROHN, J. L, LINENBERGER, M. L, HOOVER, E. A, OVERBAUGH, J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Physio-chemical and antibacterial characteristics of pressure spun nylon nanofibres embedded with functional silver nanoparticles by Xu, Z., Mahalingam, S., Rohn, J.L., Ren, G., Edirisinghe, M.

“…A novel and facile approach to prepare hybrid nanoparticle embedded polymer nanofibers using pressurised gyration is presented. Silver nanoparticles and nylon…”
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Viral genetic variation, AIDS, and the multistep nature of carcinogenesis: the feline leukemia virus model by Rohn, J L, Gwynn, S R, Lauring, A S, Linenberger, M L, Overbaugh, J

“…Feline leukemia virus (FeLV) infection in cats serves as a valuable animal model system for understanding the mechanisms of human diseases such as cancer and…”
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Importance of Nuclear Localization of Apoptin for Tumor-specific Induction of Apoptosis by Danen-van Oorschot, Astrid A.A.M., Zhang, Ying-Hui, Leliveld, S.Rutger, Rohn, Jennifer L., Seelen, Maud C.M.J., Bolk, Marian W., van Zon, Arend, Erkeland, Stefan J., Abrahams, Jan-Pieter, Mumberg, Dominik, Noteborn, Mathieu H.M.

“…The chicken anemia virus-derived protein Apoptin induces apoptosis specifically in human tumor and transformed cells and not in normal, untransformed cells…”
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Viral genetic variation, AIDS, and the multistep nature of carcinogenesis : the feline leukemia virus model by ROHN, J. L, GWYNN, S. R, LAURING, A. S, LINENBERGER, M. L, OVERBAUGH, J

“…Feline leukemia virus (FeLV) infection in cats serves as a valuable animal model system for understanding the mechanisms of human diseases such as cancer and…”
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A Tumor-specific Kinase Activity Regulates the Viral Death Protein Apoptin by Rohn, Jennifer L., Zhang, Ying-Hui, Aalbers, Remco I.J.M., Otto, Norbert, den Hertog, Jeroen, Henriquez, Niek V., van de Velde, Cornelis J.H., Kuppen, Peter J.K., Mumberg, Dominik, Donner, Peter, Noteborn, Mathieu H.M.

“…Apoptin, a chicken anemia virus-encoded protein, is thought to be activated by a general tumor-specific pathway, because it induces apoptosis in a large number…”
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Recombinant apoptin multimers kill tumor cells but are nontoxic and epitope-shielded in a normal-cell-specific fashion by Zhang, Ying-Hui, Leliveld, S.Rutger, Kooistra, Klaas, Molenaar, Chris, Rohn, Jennifer L, Tanke, Hans J, Abrahams, Jan Pieter, Noteborn, Mathieu H.M

“…Apoptin, a protein derived from chicken anemia virus, induces apoptosis in human transformed or tumor cells but not in normal cells. When produced in bacteria…”
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Apoptin Induces Tumor-specific Apoptosis as a Globular Multimer by Leliveld, Sirik R, Zhang, Ying-Hui, Rohn, Jennifer L, Noteborn, Mathieu H M, Abrahams, Jan Pieter

“…The chicken anemia virus-derived Apoptin protein induces tumor-specific apoptosis. Here, we show that recombinant Apoptin protein spontaneously forms…”
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Apoptin protein multimers form distinct higher‐order nucleoprotein complexes with DNA by Leliveld, Sirik R., Dame, Remus T., Mommaas, Mieke A., Koerten, Henk K., Wyman, Claire, Danen‐van Oorschot, Astrid A. A. M., Rohn, Jennifer L., Noteborn, Mathieu H. M., Abrahams, Jan Pieter

“…The chicken anaemia virus‐derived protein apoptin is a tumour‐specific cell‐killing agent. It is biologically active as a highly stable, multimeric complex,…”
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Changes in Ect2 Localization Couple Actomyosin-Dependent Cell Shape Changes to Mitotic Progression by Matthews, Helen K., Delabre, Ulysse, Rohn, Jennifer L., Guck, Jochen, Kunda, Patricia, Baum, Buzz

“…As they enter mitosis, animal cells undergo profound actin-dependent changes in shape to become round. Here we identify the Cdk1 substrate, Ect2, as a central…”
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In vivo evolution of a novel, syncytium-inducing and cytopathic feline leukemia virus variant by Rohn, J.L, Moser, M.S, Gwynn, S.R, Baldwin, D.N, Overbaugh, J

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Feline Leukemia Virus Envelope Sequences That Affect T-Cell Tropism and Syncytium Formation Are Not Part of Known Receptor-Binding Domains by Gwynn, S R, Hankenson, F C, Lauring, A S, Rohn, J L, Overbaugh, J

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Akt mediates insulin rescue from apoptosis in brown adipocytes: effect of ceramide by Navarro, Paloma, Valverde, Angela M., Rohn, Jennifer L., Benito, Manuel, Lorenzo, Margarita

“…We have recently shown that insulin can rescue serum deprived adipocytes from apoptosis in a PI 3 kinase and MAP kinase dependent manner. This study…”
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