Search Results - "ROHDE, H"

Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection by Rohde, Kyle H, Veiga, Diogo F T, Caldwell, Shannon, Balázsi, Gábor, Russell, David G

“…Intracellular pathogens such as Mycobacterium tuberculosis have evolved strategies for coping with the pressures encountered inside host cells. The ability to…”
Get full text

Functional genetic diversity among Mycobacterium tuberculosis complex clinical isolates: delineation of conserved core and lineage-specific transcriptomes during intracellular survival by Homolka, Susanne, Niemann, Stefan, Russell, David G, Rohde, Kyle H

“…Tuberculosis exerts a tremendous burden on global health, with approximately 9 million new infections and approximately 2 million deaths annually. The…”
Get full text

Mycobacterium tuberculosis invasion of macrophages: linking bacterial gene expression to environmental cues by Rohde, Kyle H, Abramovitch, Robert B, Russell, David G

“…A central feature of Mycobacterium tuberculosis (Mtb) pathogenesis is the ability of Mtb to survive within macrophages (MØ). Despite its critical importance,…”
Get full text

The Prospective Synergy of Antitubercular Drugs With NAD Biosynthesis Inhibitors by Rohde, Kyle H, Sorci, Leonardo

“…Given the upsurge of drug-resistant tuberculosis worldwide, there is much focus on developing novel drug combinations allowing shorter treatment duration and a…”
Get full text

Orphan response regulator NnaR is critical for nitrate and nitrite assimilation in Mycobacterium abscessus by Simcox, Breven S, Rohde, Kyle H

“…( ) is an opportunistic pathogen afflicting individuals with underlying lung disease such as Cystic Fibrosis (CF) or immunodeficiencies. Current treatment…”
Get full text

DNA nanotechnology for nucleic acid analysis: multifunctional molecular DNA machine for RNA detection by Cox, A J, Bengtson, H N, Rohde, K H, Kolpashchikov, D M

“…The Nobel prize in chemistry in 2016 was awarded for 'the design and synthesis of molecular machines'. Here we designed and assembled a molecular machine for…”
Get more information

Implementation of a multidisciplinary infections conference improves the treatment of spondylodiscitis by Ntalos, D., Schoof, B., Thiesen, D. M., Viezens, L., Kleinertz, H., Rohde, H., Both, A., Luebke, A., Strahl, A., Dreimann, M., Stangenberg, M.

“…Establishing a multidisciplinary approach regarding the treatment of spondylodiscitis and analyzing its effect compared to a single discipline approach. 361…”
Get full text

Anticipating explanations in relative clause processing by Rohde, H., Levy, R., Kehler, A.

“…We show that comprehenders’ expectations about upcoming discourse coherence relations influence the resolution of local structural ambiguity. We employ cases…”
Get full text

ramR Mutations in Clinical Isolates of Klebsiella pneumoniae with Reduced Susceptibility to Tigecycline by HENTSCHKE, M, WOLTERS, M, SOBOTTKA, I, ROHDE, H, AEPFELBACHER, M

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Atypical Mycobacterium abscessus BlaRI Ortholog Mediates Regulation of Energy Metabolism but Not β‐Lactam Resistance by Bonefont, Lauren E., Davenport, Haley C., Chaton, Catherine T., Korotkov, Konstantin V., Rohde, Kyle H.

“…ABSTRACT Mycobacterium abscessus (Mab) is highly drug resistant, and understanding regulation of antibiotic resistance is critical to future antibiotic…”
Get full text

A pharmacokinetic-pharmacodynamic (PKPD) model-based analysis of tedizolid against enterococci using the hollow-fibre infection model by Iqbal, K, Rohde, H, Huang, J, Tikiso, T, Amann, L F, Zeitlinger, M, Wicha, S G

“…Tedizolid is a novel oxazolidinone antibiotic. Considering the higher antibacterial effect in immunocompetent compared with immunosuppressed animals, it is not…”
Get full text

Mycobacterium abscessus DosRS two-component system controls a species-specific regulon required for adaptation to hypoxia by Simcox, Breven S, Tomlinson, Brooke R, Shaw, Lindsey N, Rohde, Kyle H

“…( ), an emerging opportunistic pathogen, predominantly infects individuals with underlying pulmonary diseases such as cystic fibrosis (CF). Current treatment…”
Get full text

The challenge of post-mortem GHB analysis: storage conditions and specimen types are both important by Kietzerow, J., Otto, B., Wilke, N., Rohde, H., Iwersen-Bergmann, S., Andresen-Streichert, H.

“…Background For the interpretation of concentrations of gamma-hydroxybutyrate (GHB) in post-mortem specimens, a possible increase due to post-mortem generation…”
Get full text

Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection by Cumming, Bridgette M, Rahman, Md Aejazur, Lamprecht, Dirk A, Rohde, Kyle H, Saini, Vikram, Adamson, John H, Russell, David G, Steyn, Adrie J C

“…Signals modulating the production of Mycobacterium tuberculosis (Mtb) virulence factors essential for establishing long-term persistent infection are unknown…”
Get full text

Implementation of a multidisciplinary infections conference affects the treatment plan in prosthetic joint infections of the hip: a retrospective study by Ntalos, Dimitris, Berger-Groch, J., Rohde, H., Grossterlinden, L. G., Both, A., Luebke, A., Hartel, M. J., Klatte, T. O.

“…Introduction Establishing a systematic multidisciplinary approach in the treatment of prosthetic joint infections (PJI) of the hip and analyzing its effect on…”
Get full text

Combined Effects of Simulated Microgravity and Radiation Exposure on Osteoclast Cell Fusion by Shanmugarajan, Srinivasan, Zhang, Ye, Moreno-Villanueva, Maria, Clanton, Ryan, Rohde, Larry H, Ramesh, Govindarajan T, Sibonga, Jean D, Wu, Honglu

“…The loss of bone mass and alteration in bone physiology during space flight are one of the major health risks for astronauts. Although the lack of weight…”
Get full text

Intramolecularly Sulfur-Stabilized Silicon Cations as Lewis Acid Catalysts by Rohde, Volker H. G, Pommerening, Phillip, Klare, Hendrik F. T, Oestreich, Martin

“…The synthesis and spectroscopic characterization of previously unprecedented sulfur-stabilized silicon cations are reported. Several 1,3-dithiolan-2-yl- and…”
Get full text

Rapid identification of the vanA/vanB resistance determinant in Enterococcus sp. from blood cultures using the Cepheid Xpert vanA/vanB cartridge system by Both, A, Berneking, L, Berinson, B, Lütgehetmann, M, Christner, M, Aepfelbacher, M, Rohde, H

“…Especially in immunocompromised and intensive care patients VRE sepsis is associated with high mortality. The GeneXpert vanA/vanB assay is marketed for fast…”
Get full text

Molecular drug susceptibility testing and strain typing of tuberculosis by DNA hybridization by Wood, Hillary N, Venken, Tom, Willems, Hanny, Jacobs, An, Reis, Ana Júlia, Almeida da Silva, Pedro Eduardo, Homolka, Susanne, Niemann, Stefan, Rohde, Kyle H, Hooyberghs, Jef

“…In Mycobacterium tuberculosis (Mtb) the detection of single nucleotide polymorphisms (SNPs) is of high importance both for diagnostics, since drug resistance…”
Get full text

Ferrocene-Stabilized Silicon Cations as Catalysts for Diels–Alder Reactions: Attempted Experimental Quantification of Lewis Acidity and ReactIR Kinetic Analysis by Nödling, Alexander R, Müther, Kristine, Rohde, Volker H. G, Hilt, Gerhard, Oestreich, Martin

“…The 29Si NMR chemical shifts of ferrocene-stabilized silicon cations span a wide range depending on the substituents at the silicon atom. These pronounced…”
Get full text