Search Results - "ROGY, M. A"

Transfer of interleukin-4 and interleukin-10 in patients with severe inflammatory bowel disease of the rectum by Rogy, M A, Beinhauer, B G, Reinisch, W, Huang, L, Pokieser, P

“…Inflammatory bowel disease (IBD) comprises the two disorders ulcerative colitis (UC) and Crohn's disease (CD). Although the etiology is still unclear,…”
Get more information

Persistently elevated soluble tumor necrosis factor receptor and interleukin-1 receptor antagonist levels in critically ill patients by ROGY, M. A, COYLE, S. M, OLDENBURG, H. S. A, ROCK, C. S, BARIE, P. S, VAN ZEE, K. J, MOLDAWER, L. L, LOWRY, S. F

“…The appearance of endogenously produced inhibitors against tumor necrosis factor (TNF) (soluble TNF-receptor type I, sTNFR-I) and interleukin-1 (IL-1 receptor…”
Get full text

The Role of Cytokines in Cancer Cachexia by Moldawer, Lyle L., Rogy, Michael A., Lowry, Stephen F.

“…There is, at present, considerable interest in the possible role for the proinflammatory cytokines, tumor necrosis factor-α, interleukin-1, interleukin-6, and…”
Get full text

Cachexia and the acute-phase protein response in inflammation are regulated by interleukin-6 by Oldenburg, H S, Rogy, M A, Lazarus, D D, Van Zee, K J, Keeler, B P, Chizzonite, R A, Lowry, S F, Moldawer, L L

“…Cachexia and the acute-phase response are common manifestations of inflammation and are presumed to be the product of increased synthesis and release of…”
Get more information

Human tumor necrosis factor receptor (p55) and interleukin 10 gene transfer in the mouse reduces mortality to lethal endotoxemia and also attenuates local inflammatory responses by Rogy, M A, Auffenberg, T, Espat, N J, Philip, R, Remick, D, Wollenberg, G K, Copeland, 3rd, E M, Moldawer, L L

“…Anticytokine therapies have been promulgated in gram-negative sepsis as a means of preventing or neutralizing excessive production of proinflammatory…”
Get full text

Correlation between acute physiology and chronic health evaluation (APACHE) III score and immunological parameters in critically ill patients with sepsis by Rogy, M. A., Oldenburg, H. S. A., Coyle, S., Trousdale, R., Moldawer, L. L., Lowry, S. F.

“…A relationship between physiological parameters of severe sepsis and immunological function has not been established. In ten severely ill patients with sepsis…”
Get full text

A human tumor necrosis factor (TNF) α mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon by VAN ZEE, K. J, STACKPOLE, S. A, ETTLIN, U, WIPF, B, LESSLAUER, W, LOWRY, S. F, MOLDAWER, L. L, MONTEGUT, W. J, ROGY, M. A, CALVANO, S. E, HSU, K. C, MOSES CHAO, MESCHTER, C. L, LOETSCHER, H, STÜBER, D

“…A number of recent studies have demonstrated that cellular responses to tumor necrosis factor (TNF) mediated by the p55 and the p75 TNF receptors are distinct…”
Get full text

Interleukin-10-deficient mice and inflammatory bowel disease associated cancer development by Sturlan, Sanda, Oberhuber, Georg, Beinhauer, Britta G., Tichy, Brigitte, Kappel, Sonja, Wang, Jacob, Rogy, Michael A.

“…Interleukin-10-deficient mice develop colitis and colorectal cancer similar to the inflammatory bowel disease associated cancer in humans. The aim of this…”
Get full text

REOPERATION AFTER CHOLECYSTECTOMY. THE ROLE OF THE CYSTIC DUCT STUMP by Rogy, M A, Függer, R, Herbst, F, Schulz, F

“…The so-called ＂Postcholecystectomy Syndrome＂ may be due to various pathological biliary causes. The aim of this study was to evaluate the significance of the…”
Get full text

Pneumatosis cystoides intestinalis (PCI) by ROGY, M. A, MIRZA, D. F, KOVATS, E, RAUHS, R

“…Pneumatosis cystoides intestinalis (PCI) is a rare disease usually occurring in association with a large variety of gastrointestinal (GI) and non GI conditions…”
Get full text

CCK-8 and gastrin plasma levels in cholecystectomized and colorectal cancer patients by ROGY, M. A, KOVATS, E, KOSS, G, MÜLLER, M, FÜGGER, R, STEININGER, R, PILZ, E, RAUHS, R, FRITSCH, A

“…The elevated incidence of large bowel carcinoma after cholecystectomy has long been controversial. The pathomechanism of this entity, however, is still…”
Get full text

The role of bactericidal/permeability-increasing protein in the treatment of primate bacteremia and septic shock by ROGY, M. A, OLDENBURG, H. S. A, LOWRY, S. F, CALVANO, S. E, MONTEGUT, W. J, STACKPOLE, S. A, VAN ZEE, K. J, MARRA, M. N, SCOTT, R. W, SEILHAMMER, J. J, MALDAWER, L. L

“…Human neutrophil azurophilic granules contain an approximately 55-kDa protein, known as bactericidal/permeability-increasing protein (BPI), which possesses a…”
Get full text

Gene transfer with IL‐4 and IL‐13 improves survival in lethal endotoxemia in the mouse and ameliorates peritoneal macrophages immune competence by Baumhofer, Julie M., Beinhauer, Brigitte G., Wang, Jacob E., Brandmeier, Helge, Geissler, Klaus, Losert, Udo, Philip, Ramila, Aversa, Gregorio, Rogy, Michael A.

“…Systemic anti‐cytokine therapies have been unsuccessful in preventing mortality from gram‐negative bacteremia in humans partly because of the failure to…”
Get full text

Anti-endotoxin therapy in primate bacteremia with HA-1A and BPI by ROGY, M. A, MOLDAWER, L. L, OLDENBURG, H. S. A, THOMPSON, W. A, MONTEGUT, W. J, STACKPOLE, S. A, ASHWINI KUMAR, PALLADINO, M. A, MARRA, M. N, LOWRY, S. F

“…The in vivo neutralizing activities of an anti-lipopolysaccharide (LPS) antibody HA-1A (Centoxin [Centocor, Malvern, PA]), a human immunoglobulin M monoclonal…”
Get full text

Protection against lethal Escherichia coli bacteremia in baboons (Papio anubis) by pretreatment with a 55-kDa TNF receptor (CD120a)-Ig fusion protein, Ro 45-2081 by Van Zee, KJ, Moldawer, LL, Oldenburg, HS, Thompson, WA, Stackpole, SA, Montegut, WJ, Rogy, MA, Meschter, C, Gallati, H, Schiller, CD, Richter, WF, Loetscher, H, Ashkenazi, A, Chamow, SM, Wurm, F, Calvano, SE, Lowry, SF, Lesslauer, W

“…Fusion proteins of the human 55-kDa TNF receptor extracellular domain with hinge and C2/C3 constant domains of human IgG1 or IgG3 heavy chains were tested in a…”
Get full text

CMNSG Guest Lecture. Interleukin-1, interleukin-1 receptor, and interleukin-1 receptor antagonist by Espat, N J, Rogy, M A, Copeland, E M, Moldawer, L L

Get full text

Interleukin 1 binding to its type I, but not type II receptor, modulates the in vivo acute phase response by Oldenburg, Hester S.A., Oldenburg, Hester S.A., Pruitt, Jeffrey H., Lazarus, Douglas D., Lazarus, Douglas D., Rogy, Michael A., Rogy, Michael A., Chizzonite, Richard, Lowry, Stephen F., Moldawer, Lyle L., Moldawer, Lyle L.

“…Neutralizing monoclonal antibodies against the murine interleukin 1 (IL-1) type I (mAb 35F5) and type II receptor (mAb 4E2) were used to passively immunize…”
Get full text

Gene therapy in surgery: Part II: Application to septic shock and to organ transplantation by Rogy, M. A., Baumhofer, Julie M., Beinhauer, Britta, Brandmeier, H., Eisenburger, P., Losert, U. M., Philip, Ramila

Get full text

Interleukin-1, interleukin-1 receptor, and interleukin-1 receptor antagonist by Espat, N. Joseph, Rogy, Michael A., Copeland, Edward M., Moldawer, Lyle L.

Get full text

In vivo gene transfer of murine interleukin-4 inhibits colon-26-mediated cancer cachexia in mice by Sturlan, Sanda, Beinhauer, Britta G, Oberhuber, Georg, Huang, Leaf, Aasen, Ansgar O, Rogy, Michael A

“…Cancer cachexia has been suggested to be mediated by various cytokines derived either from tumor or host tissue. In the murine colon-26 (C-26) adenocarcinoma…”
Get more information