Search Results - "ROGUET, Roland"

ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity Function Test by Spielmann, Horst, Hoffmann, Sebastian, Liebsch, Manfred, Botham, Phil, Fentem, Julia H, Eskes, Chantra, Roguet, Roland, Cotovio, José, Cole, Thomas, Worth, Andrew, Heylings, Jon, Jones, Penny, Robles, Catherine, Kandárova, Helena, Gamer, Armin, Remmele, Marina

“…ECVAM sponsored a formal validation study on three in vitro tests for skin irritation, of which two employ reconstituted human epidermis models (EPISKIN,…”
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In Vivo Correlation Between Stratum Corneum Reservoir Function and Percutaneous Absorption by Rougier, Andre, Dupuis, Didier, Schaefer, Hans, Lotte, Claire, Roguet, Roland

“…A relationship between stratum corneum reservoir function and percutaneous absorption has been established in the hairless rat. Two hundred nanomoles of 10…”
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The Measurement of the Stratum Corneum Reservoir. A Predictive Method for In Vivo Percutaneous Absorption Studies: Influence of Application Time by Rougier, Andre, Dupuis, Didier, Lotte, Claire, Roguet, Roland

“…The relation existing in vivo between the reservoir function of the stratum corneum following a 30-mm application time and the total percutaneous absorption of…”
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in vitro acute skin irritation of chemicals: Optimisation of the EPISKIN prediction model within the framework of the ECVAM validation process by Cotovio, J, Grandidier, M.H, Portes, P, Roguet, R, Rubinstenn, G

“…In view of the increasing need to identify non-animal tests able to predict acute skin irritation of chemicals, the European Centre for the Validation of…”
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The use of reconstructed human epidermis EPISKIN in the assessment of local tolerance of cosmetics and chemicals by Roguet, Roland

“…Models of reconstructed human skin provide useful tools for both basic research and evaluation of the safety and efficacy of dermato-cosmetological products…”
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In vitro acute skin irritancy of 184 cosmetic ingredients using the validated EPISKIN model protocol by Cotovio, José, Grandidier, Marie-Hélène, Lelievre, Damien, Alepee, Nathalie, Roguet, Roland, Tinois-Tessonneaud, Estelle, Leclaire, Jacques

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Percutaneous absorption and dermal toxicity by Schaefer, Hans, Roguet, Roland

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The in vitro skin irritation of chemicals: optimisation of the EPISKIN prediction model within the framework of the ECVAM validation process by Cotovio, Jose, Grandidier, Marie-Helene, Portes, Pascal, Roguet, Roland, Rubinstenn, Gilles

“…In view of the increasing need to identify non-animal tests able to predict acute skin irritation of chemicals, the European Centre for the Validation of…”
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Follow-up to the ECVAM prevalidation study on in vitro tests for acute skin Irritation. ECVAM Skin Irritation Task Force Report 2 by ZUANG, Valérie, BALLS, Michael, MEDINA, Jesus, ROGUET, Roland, VAN DE SANDT, Johannes J. M, WIEMANN, Christianne, WORTH, Andrew P, BOTHAM, Philip A, COQUETTE, Alain, CORSINI, Emanuela, CURREN, Rodger D, ELLIOTT, Graham R, FENTEM, Julia H, HEYLINGS, Jon R, LIEBSCH, Manfred

“…The European Centre for the Validation of Alternative Methods (ECVAM) Skin Irritation Task Force was established in 1996, to review the status of the…”
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Iron chelation can modulate UVA-induced lipid peroxidation and ferritin expression in human reconstructed epidermis by Seité, Sophie, Popovic, Evelyne, Verdier, Marie Paule, Roguet, Roland, Portes, Pascal, Cohen, Catherine, Fourtanier, Anny, Galey, Jean Baptiste

“…Background/Purpose: As ferritin has been identified as an important factor in antioxidant defense in cultured human skin cells, we evaluated UVA‐induced lipid…”
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The use of human keratinocytes and human skin models for predicting skin irritation : The report and recommendations of ECVAM Workshop 38 by DE SANDT, J. V, ROGUET, R, DE BRUGEROLLE DE FRAISSINETTE, A, FARTASCH, M, COHEN, C, ESDAILE, D, PONEC, M, CORSINI, E, BARKER, C, FUSENIG, N, LIEBSCH, M, BENFORD, D

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The ECVAM International Validation Study on In Vitro Tests for Acute Skin Irritation : Report on the Validity of the EPISKIN and EpiDerm Assays and on the Skin Integrity Function Testa by SPIELMANN, Horst, HOFFMANN, Sebastian, HEYLINGS, Jon, JONES, Penny, ROBLES, Catherine, KANDAROVA, Helena, GAMER, Armin, REMMELE, Marina, CURREN, Rodger, RAABE, Hans, COCKSHOTT, Amanda, GERNER, Ingrid, LIEBSCH, Manfred, ZUANG, Valérie, BOTHAM, Phil, FENTEM, Julia H, ESKES, Chantra, ROGUET, Roland, COTOVIO, José, COLE, Thomas, WORTH, Andrew

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Follow-up to the ECVAM prevalidation study on in vitro tests for acute skin irritation. The European Centre for the Validation of Alternative Methods Skin Irritation Task Force report 2 by Zuang, Valérie, Balls, Michael, Botham, Philip A, Coquette, Alain, Corsini, Emanuela, Curren, Rodger D, Elliott, Graham R, Fentem, Julia H, Heylings, Jon R, Liebsch, Manfred, Medina, Jesús, Roguet, Roland, van de Sandt, Johannes J M, Wiemann, Christianne, Worth, Andrew P

“…The European Centre for the Validation of Alternative Methods (ECVAM) Skin Irritation Task Force was established in 1996, to review the status of the…”
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Selective induction of interleukin-12 in reconstructed human epidermis by chemical allergens by CORSINI, E, LIMIROLI, E, MARINOVICH, M, COHEN, C, ROGUET, R, GALLI, C. L

“…Keratinocytes play an important role in skin inflammatory and immunological reactions through the release of cytokines and response to them. These cells have…”
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In Vivo Relationship Between Horny Layer Reservoir Effect and Percutaneous Absorption in Human and Rat by Dupuis, Didier, Rougier, Andre, Roguet, Roland, Lotte, Claire, Kalopissis, Gregoire

“…The in vivo relationship between the reservoir effect of the stratum corneum and the percutaneous absorption was established in both human volunteers and…”
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Evidence for an age-correlated change in glutathione metabolism enzyme activities in human hair follicle by Kermici, M, Pruche, F, Roguet, R, Prunieras, M

“…In this investigation, glutathione peroxidase (GSH-PX), glutathione reductase (GSSG-RD), glutathione-S-transferase (GSH-S-T), gamma-glutamyl transpeptidase…”
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Short Communications. Changes in lectin-induced deoxyribonucleic acid synthesis in cultures of chick-embryo fibroblasts at various stages of development by Roguet, Roland, Bourrillon, Roland

“…Concanavalin A and Robinia pseudoacacia lectin decreased [3H]thymidine incorporation into acid-insoluble material of fibroblasts cultured from 6–10-day chick…”
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Interaction between Dolichos biflorus lectin and chick embryonic fibroblasts at different stages of development by Roguet, R, Bourrillon, R

“…The interaction between chick embryo fibroblasts and A1-specific blood group Dolichos biflorus lectin has been studied at various stages of embryo development…”
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Changes in lectin-induced deoxyribonucleic acid synthesis in cultures of chick-embryo fibroblasts at various stages of development by Roguet, R, Bourrillon, R

“…Concanavalin A and Robinia pseudoacacia lectin decreased [(3)H]thymidine incorporation into acid-insoluble material of fibroblasts cultured from 6-10-day chick…”
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