Search Results - "ROGIERS, V"

Quantitative Risk Assessment in the EU of Cosmetics for Babies and Children by Rogiers, V.

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Connexin-related signaling in cell death: to live or let die? by Decrock, E, Vinken, M, De Vuyst, E, Krysko, D V, D'Herde, K, Vanhaecke, T, Vandenabeele, P, Rogiers, V, Leybaert, L

“…Evidence is accumulating that some forms of cell death, like apoptosis, are not only governed by the complex interplay between extracellular and intracellular…”
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Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies by Fraczek, J., Bolleyn, J., Vanhaecke, T., Rogiers, V., Vinken, M.

“…Continuously increasing understanding of the molecular triggers responsible for the onset of diseases, paralleled by an equally dynamic evolution of chemical…”
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Overview of skin whitening agents with an insight into the illegal cosmetic market in Europe by Desmedt, B., Courselle, P., De Beer, J.O., Rogiers, V., Grosber, M., Deconinck, E., De Paepe, K.

“…Lightening skin tone is an ancient and well‐documented practice, and remains common practice among many cultures. Whitening agents such as corticosteroids,…”
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Drug-induced liver injury: mechanisms, types and biomarkers by Vinken, M, Maes, M, Vanhaecke, T, Rogiers, V

“…Drug-induced liver injury is a ubiquitous issue in clinical settings and pharmaceutical industry. Hepatotoxicity elicited by drugs may be intrinsic or…”
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Human health safety evaluation of cosmetics in the EU: A legally imposed challenge to science by Pauwels, M., Rogiers, V.

“…As stated in the European legislation, cosmetic products present on the European market must be safe for the consumer. Safety evaluation of the products is…”
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HS–GC–MS method for the analysis of fragrance allergens in complex cosmetic matrices by Desmedt, B., Canfyn, M., Pype, M., Baudewyns, S., Hanot, V., Courselle, P., De Beer, J.O., Rogiers, V., De Paepe, K., Deconinck, E.

“…Potential allergenic fragrances are part of the Cosmetic Regulation with labelling and concentration restrictions. This means that they have to be declared on…”
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Workshop on acceleration of the validation and regulatory acceptance of alternative methods and implementation of testing strategies by Piersma, A.H., Burgdorf, T., Louekari, K., Desprez, B., Taalman, R., Landsiedel, R., Barroso, J., Rogiers, V., Eskes, C., Oelgeschläger, M., Whelan, M., Braeuning, A., Vinggaard, A.M., Kienhuis, A., van Benthem, J., Ezendam, J.

“…This report describes the proceedings of the BfR-RIVM workshop on validation of alternative methods which was held 23 and 24 March 2017 in Berlin, Germany…”
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Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model by Decrock, E, De Vuyst, E, Vinken, M, Van Moorhem, M, Vranckx, K, Wang, N, Van Laeken, L, De Bock, M, D'Herde, K, Lai, C P, Rogiers, V, Evans, W H, Naus, C C, Leybaert, L

“…Gap junctions (GJs) have been demonstrated to communicate cell death signals from apoptotic to healthy cells, thereby spatially extending apoptosis. Before…”
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Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients by Dent, M.P., Vaillancourt, E., Thomas, R.S., Carmichael, P.L., Ouedraogo, G., Kojima, H., Barroso, J., Ansell, J., Barton-Maclaren, T.S., Bennekou, S.H., Boekelheide, K., Ezendam, J., Field, J., Fitzpatrick, S., Hatao, M., Kreiling, R., Lorencini, M., Mahony, C., Montemayor, B., Mazaro-Costa, R., Oliveira, J., Rogiers, V., Smegal, D., Taalman, R., Tokura, Y., Verma, R., Willett, C., Yang, C.

“…Next generation risk assessment (NGRA) is an exposure-led, hypothesis-driven approach that has the potential to support animal-free safety decision-making…”
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Consumer protection provided by the European medical device and cosmetic legislation for condoms and lubricants by Desmedt, B., Vanhamme, M., Vanhee, C., Rogiers, V., Deconinck, E.

“…Personal lubricants and lubricants used in condoms contain a number of ingredients which are also present in cosmetic products. These have to comply to the…”
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Coatings in food contact materials: Potential source of genotoxic contaminants? by Mertens, Birgit, Van Bossuyt, M., Fraselle, S., Blaude, M.N., Vanhaecke, T., Rogiers, V., Verschaeve, L., Van Hoeck, E.

“…Up till now, no harmonized EU regulation exists on chemicals used in coatings for food contact materials (FCM). Therefore, these substances need to comply with…”
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Development and validation of a fast chromatographic method for screening and quantification of legal and illegal skin whitening agents by Desmedt, B., Rogiers, V., Courselle, P., De Beer, J.O., De Paepe, K., Deconinck, E.

“…•New UHPLC-DAD method capable of analyzing illegal skin whitening cosmetics.•Detection of legal and illegal skin whitening agents.•The method is validated for…”
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Reprogramming of human umbilical cord-derived mesenchymal stromal cells into hepatocyte-like cells by over-expression of hepatocyte nuclear factor 1-alpha by Buyl, K, Rodrigues, R.M, Rogiers, V, De Kock, J, Vanhaecke, T

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Characterization of suspected illegal skin whitening cosmetics by Desmedt, B., Van Hoeck, E., Rogiers, V., Courselle, P., De Beer, J.O., De Paepe, K., Deconinck, E.

“…•UHPLC–ToF–MS method for screening of suspected skin whitening cosmetics.•Validation for multiple matrices.•Detection and quantification of skin whitening…”
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RE-Place: A local initiative to pave the road towards international recognition and promotion of new approach methodologies by Van Mulders, M., Missigba, N. Liodo, Rogiers, V., Mertens, B.

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Human skin-derived stem cells as a novel cell source for in vitro hepatotoxicity screening of pharmaceuticals by Rodrigues, R.M., De Kock, J., Rogiers, V., Vanhaecke, T.

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Transfer of IP3 through gap junctions is critical, but not sufficient, for the spread of apoptosis by Decrock, E, Krysko, D V, Vinken, M, Kaczmarek, A, Crispino, G, Bol, M, Wang, N, De Bock, M, De Vuyst, E, Naus, C C, Rogiers, V, Vandenabeele, P, Erneux, C, Mammano, F, Bultynck, G, Leybaert, L

“…Decades of research have indicated that gap junction channels contribute to the propagation of apoptosis between neighboring cells. Inositol…”
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Steatogenic compounds induce triglyceride accumulation by multiple mechanisms in hepatocyte-like cells generated from human skin-derived precursors by Rodrigues, R.M, Boeckmans, J, Natale, A, Buyl, K, De Kock, J, Vanhaecke, T, Rogiers, V

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Silicones as nonocclusive topical agents by De Paepe, K, Sieg, A, Le Meur, M, Rogiers, V

“…Silicone excipients are commonly used ingredients because of their emollient and skin-conditioning effects, and their ability to form uniform, water-resistant,…”
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