Search Results - "ROGERS, David"
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The molecular and genetic basis of antifungal resistance in the emerging fungal pathogen Candida auris
Published in Current opinion in microbiology (01-12-2022)“…Fungal infections are responsible for significant morbidity and mortality. Resistance to the limited number of agents in the antifungal armamentarium among…”
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Addendum to the AAPM's TG-51 protocol for clinical reference dosimetry of high-energy photon beams
Published in Medical physics (Lancaster) (01-04-2014)“…An addendum to the AAPM's TG-51 protocol for the determination of absorbed dose to water in megavoltage photon beams is presented. This addendum continues the…”
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The Candida glabrata Upc2A transcription factor is a global regulator of antifungal drug resistance pathways
Published in PLoS genetics (30-09-2021)“…The most commonly used antifungal drugs are the azole compounds, which interfere with biosynthesis of the fungal-specific sterol: ergosterol. The pathogenic…”
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Addressing durable educational concerns in a rapidly changing world
Published in The American journal of surgery (01-12-2021)“…Measurement research like this requires considerable effort that is detailed in their report and perhaps one reasons that efforts like it constitute the…”
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Reflections on a life with Monte Carlo in Medical Physics
Published in Medical physics (Lancaster) (01-06-2023)“…The author reminisces about some of his experiences working with Monte Carlo techniques for Medical Physics applications…”
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Spore-autonomous fluorescent protein expression identifies meiotic chromosome mis-segregation as the principal cause of hybrid sterility in yeast
Published in PLoS biology (12-11-2018)“…Genome-wide sequence divergence between populations can cause hybrid sterility through the action of the anti-recombination system, which rejects crossover…”
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7
Three practical workflow schedulers for easy maximum parallelism
Published in Software, practice & experience (01-01-2023)“…Runtime scheduling and workflow systems are an increasingly popular algorithmic component in HPC because they allow full system utilization with relaxed…”
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Evolution of mating types in finite populations: The precarious advantage of being rare
Published in Journal of evolutionary biology (01-11-2019)“…Sexually reproducing populations with self‐incompatibility bear the cost of limiting potential mates to individuals of a different type. Rare mating types…”
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Very fast prediction and rationalization of pKa values for protein-ligand complexes
Published in Proteins, structure, function, and bioinformatics (15-11-2008)“…The PROPKA method for the prediction of the pKa values of ionizable residues in proteins is extended to include the effect of non‐proteinaceous ligands on…”
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10
Digital Transformation: An Interview with David Rogers
Published in Research technology management (03-09-2022)Get full text
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11
An Improved Diabatization Scheme for Computing the Electronic Circular Dichroism of Proteins
Published in The journal of physical chemistry. B (01-08-2024)“…We advance the quality of first-principles calculations of protein electronic circular dichroism (CD) through an amelioration of a key deficiency of a previous…”
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Editorial overview: Recent advances in antimicrobial drug discovery and resistance
Published in Current opinion in microbiology (01-02-2023)Get full text
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Contribution of clinically derived mutations in ERG11 to azole resistance in Candida albicans
Published in Antimicrobial agents and chemotherapy (01-01-2015)“…In Candida albicans, the ERG11 gene encodes lanosterol demethylase, the target of the azole antifungals. Mutations in ERG11 that result in an amino acid…”
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14
QuantumScents: Quantum-Mechanical Properties for 3.5k Olfactory Molecules
Published in Journal of chemical information and modeling (11-12-2023)“…Quantitative structure–odor relationships are critically important for studies related to the function of olfaction. Current literature data sets contain…”
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15
Dengue: recent past and future threats
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05-04-2015)“…This article explores four key questions about statistical models developed to describe the recent past and future of vector-borne diseases, with special…”
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Risk maps of Lassa fever in West Africa
Published in PLoS neglected tropical diseases (2009)“…Lassa fever is caused by a viral haemorrhagic arenavirus that affects two to three million people in West Africa, causing a mortality of between 5,000 and…”
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The arrival, establishment and spread of exotic diseases: patterns and predictions
Published in Nature reviews. Microbiology (01-05-2010)“…Key Points Six case studies illustrate how the common emergence of exotic vector-borne zoonotic infections depends on the three sequential steps of arrival,…”
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Optimizing radionuclide sequestration in anion nanotraps with record pertechnetate sorption
Published in Nature communications (09-04-2019)“…The elimination of specific contaminants from competitors poses a significant challenge. Rather than relying on a single direct interaction, the cooperation of…”
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Origins of multicellular evolvability in snowflake yeast
Published in Nature communications (20-01-2015)“…Complex life has arisen through a series of ‘major transitions’ in which collectives of formerly autonomous individuals evolve into a single, integrated…”
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Gain-of-Function Mutations in UPC2 Are a Frequent Cause of ERG11 Upregulation in Azole-Resistant Clinical Isolates of Candida albicans
Published in Eukaryotic Cell (01-10-2012)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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